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The map label for this gene is lytC [H]

Identifier: 238916674

GI number: 238916674

Start: 741281

End: 742048

Strand: Direct

Name: lytC [H]

Synonym: EUBELI_00736

Alternate gene names: 238916674

Gene position: 741281-742048 (Clockwise)

Preceding gene: 238916673

Following gene: 238916675

Centisome position: 34.57

GC content: 34.64

Gene sequence:

>768_bases
ATGAGAGGTCATAAGACATTTAGAATTGATAAAATATTTGGTCTGGCTACTCTTGTCTGTATGCTGGTATTGGCTTTGAT
GGTTTATAATGATTTTTTTAAGTCAGTCAGTATAAGTACTGGTACAGAGAAAGAAACGCAGAATGAAACCAGAAATAATA
ACGGAATTGATAAAACAGAGAAAGAGAGTAAGCCTGCCAAAAACATAACTGTATGTCTGGATGCTGCGAAAGGCGGAAAA
GACATGGGGCTTAGTTCCAATGGAAAGAAAGAGAAGAATATAACTCTTGATATGGCTCTTGCTGTTAAAGAAAAGCTTGA
TATACAAGGGATAAATGTTGTTCTTACAAGAACTTCTGATACAGATGTAACTGATGAAGCAAGAGTAAATACATGTAATA
AATCATCAGCTAATATAGTTGTTTCTTTAAGAATGAATTCATACAATAACGATACTTCTGTATCGGGAGCAGAGAGTTAT
ATTCATACTACAAAGCCTGTGGAGGCAGCAGAATTATCAAGAAAAATACTTGCAAGCCTTGAGAAATCGGTGGGTATCAA
GAACCGTGGAGTAAAGGCTGGAACAGTTGCAGATGCAAAGGATAATTATTATATTAATGCCCATAGCAAATGTACAAGCA
CAATAATAGATATTGGCTTTATAACTAATGCATCAGATTTAAAGAAAGTAACAACTGATAAAGATAAGACAGCACAAGCC
ATAGCAGATGGCATAACAGATTATTTAAAACAAGCGGGGTTATATTAA

Upstream 100 bases:

>100_bases
GAAAATAATGCGTCAGTTAAGAAAAGAAATGGTCAAAAGTTGTTGACATTTGCCCCTTCCTTATGGACAATAGTACAAGA
AATATTAATGGAGTACTATA

Downstream 100 bases:

>100_bases
TGGCAGGAATTAATCAGAAGAACATAAGAAATTTTTGTATTATTGCACATATTGATCATGGTAAGTCAACACTGGCTGAC
AGAATTATTGAAAAAACCGG

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRGHKTFRIDKIFGLATLVCMLVLALMVYNDFFKSVSISTGTEKETQNETRNNNGIDKTEKESKPAKNITVCLDAAKGGK
DMGLSSNGKKEKNITLDMALAVKEKLDIQGINVVLTRTSDTDVTDEARVNTCNKSSANIVVSLRMNSYNNDTSVSGAESY
IHTTKPVEAAELSRKILASLEKSVGIKNRGVKAGTVADAKDNYYINAHSKCTSTIIDIGFITNASDLKKVTTDKDKTAQA
IADGITDYLKQAGLY

Sequences:

>Translated_255_residues
MRGHKTFRIDKIFGLATLVCMLVLALMVYNDFFKSVSISTGTEKETQNETRNNNGIDKTEKESKPAKNITVCLDAAKGGK
DMGLSSNGKKEKNITLDMALAVKEKLDIQGINVVLTRTSDTDVTDEARVNTCNKSSANIVVSLRMNSYNNDTSVSGAESY
IHTTKPVEAAELSRKILASLEKSVGIKNRGVKAGTVADAKDNYYINAHSKCTSTIIDIGFITNASDLKKVTTDKDKTAQA
IADGITDYLKQAGLY
>Mature_255_residues
MRGHKTFRIDKIFGLATLVCMLVLALMVYNDFFKSVSISTGTEKETQNETRNNNGIDKTEKESKPAKNITVCLDAAKGGK
DMGLSSNGKKEKNITLDMALAVKEKLDIQGINVVLTRTSDTDVTDEARVNTCNKSSANIVVSLRMNSYNNDTSVSGAESY
IHTTKPVEAAELSRKILASLEKSVGIKNRGVKAGTVADAKDNYYINAHSKCTSTIIDIGFITNASDLKKVTTDKDKTAQA
IADGITDYLKQAGLY

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 27674; Mature: 27674

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGHKTFRIDKIFGLATLVCMLVLALMVYNDFFKSVSISTGTEKETQNETRNNNGIDKTE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCH
KESKPAKNITVCLDAAKGGKDMGLSSNGKKEKNITLDMALAVKEKLDIQGINVVLTRTSD
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEECCC
TDVTDEARVNTCNKSSANIVVSLRMNSYNNDTSVSGAESYIHTTKPVEAAELSRKILASL
CCCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
EKSVGIKNRGVKAGTVADAKDNYYINAHSKCTSTIIDIGFITNASDLKKVTTDKDKTAQA
HHHCCCCCCCCCCCEEECCCCCEEEECCCHHHHHHEEEHEECCHHHHHHHHCCCHHHHHH
IADGITDYLKQAGLY
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MRGHKTFRIDKIFGLATLVCMLVLALMVYNDFFKSVSISTGTEKETQNETRNNNGIDKTE
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCH
KESKPAKNITVCLDAAKGGKDMGLSSNGKKEKNITLDMALAVKEKLDIQGINVVLTRTSD
HHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEECCC
TDVTDEARVNTCNKSSANIVVSLRMNSYNNDTSVSGAESYIHTTKPVEAAELSRKILASL
CCCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHH
EKSVGIKNRGVKAGTVADAKDNYYINAHSKCTSTIIDIGFITNASDLKKVTTDKDKTAQA
HHHCCCCCCCCCCCEEECCCCCEEEECCCHHHHHHEEEHEECCHHHHHHHHCCCHHHHHH
IADGITDYLKQAGLY
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]