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The map label for this gene is spoVD [H]

Identifier: 238916667

GI number: 238916667

Start: 733055

End: 734821

Strand: Direct

Name: spoVD [H]

Synonym: EUBELI_00729

Alternate gene names: 238916667

Gene position: 733055-734821 (Clockwise)

Preceding gene: 238916666

Following gene: 238916668

Centisome position: 34.19

GC content: 40.58

Gene sequence:

>1767_bases
ATGAAGGATAATGACACATTTGGCTGGCTCAGCACCAGTCATAGAAAAAAGCTTGTGTTAATGATAGCTGCAATCCTTAT
GGTTTGTATTCTTGAATGCGTAAGGCTTGGCGTTATTATGACGGTAAAGTCAGAGTATTATATGCAAAAGGCTGATGAGC
TGCATCAACGGGAGAGAAGAATTAAGGCAAAGAGAGGAAGGATTCTTGACAGAAATGGCGAAATACTTGCAGCTAATGAA
GTGGTATGTACAGTTTCTGTAATACATAGTCAGATAGAGGACGAAGATAAGGTTATAAAAGTGCTTGCAGGTGAACTTGA
TATGGATGTGGAGGAAGTGACTAAGAAAGTAAAAAAAGTATCCTCTATGGAATATATTAAGACAAATGTGGCAAAGGATA
TCGGAGATGCAATAAGGGAATACGACCTGCCGGGTGTAAAGATTGACGAGGATTATAAGCGGGTATATCCGTATAATGAA
CTGGCTTCCAAAGTACTTGGCTTTACTGGTGCTGATAATCAGGGAATACTTGGGCTGGAAGCTAAATATGACACATATCT
GTCAGGTACTAATGGTCAGATTCTTACACTGTCTGATGCAGGGGGGATTGAGATAAAGGGCAGCCGGGAAGATCGTATTC
TACCGGTTGACGGACAGGATCTGTATACAACGCTTGATGTTAATATACAGAAATATGCAACCCAGCTTGCATGGGAGACT
ATGGTAAAGAAAGAGGCAAAACAGGTAAGCATAATTGTAATGCGTCCGGATAATGGAGAGATACTTGCCATGGCAAATGT
TCCGGAATACAATCTTAATTCTCCGTATGAGCTTAATTATGAGCCTGATGAGGAAGAGACACAGAAGGATAAGATGGATC
TTCTTAATAATATGTGGCGGAATTTCTGCATAAATGATACATATGAACCAGGCTCAATATTTAAGACGGTTACTGCAACA
GCAGCACTTGAGACAGGCGTGGTGGGTTTAAATGATTCTTTCACATGTTCAGGTGCAACAGTTGTTTCTGACAGAAGAAT
AAGATGTCACAAAACAACAGGACATGGAACACAGGATTTTACACATACAGTGTATAATTCGTGTAATCCGGCATTTGTTG
AATGGGGCAGAAGAGTCGGTACTGATAATATGTATCTGTACATGGGTAAGCTTGGACTTCTTGCAAAGACAGGAATAGAT
CTGTCAGGAGAGGCAGGAACGATTATTCATAAGCAGGAAAATGTAGGTGCGGTTGAGCTTGCCACAATGTCATTCGGACA
GTCTTTCCAGATAACACCCGTTCAGATGTTAAGGGCTGTCTCGGCAATTGTAAATGGTGGAAGACTTGTTACACCACATT
TTGGCTTATACACAGGTTCATCAGATGGTTCAGTGGTAAATGAATTTGCATATTCAACACAGGATGAGGCAATATCATCC
CAAACGAGTGAAACGATGAAAAAGATTCTTGAGGGTGTAGTGTCAGAAGGCGGAGGAACGAAAGCATATATTGACGGCTA
TTCAATAGGAGGAAAAACGGCAACATCACAGAAGCTGCCAAGAGGTTCAGGAAAATATATTTCATCATTCATAGGTTTTG
CTCCGGCTGATAATCCACAGGTTATAGCGATGTGCTTAATTGATGAACCAACAGGCGTATATTATGGTGGAACGATTGCT
GCTCCTGTTGTTAAGACACTGTATGAAAATATATTGCCGTATATTGGTATAGAAAGGTCAGTTCAACTTGAAAAAAACGA
TGATTGA

Upstream 100 bases:

>100_bases
CAGCTACGACAGGCAGCAACTAAAATTATGTAATAATAAGTAGAATAACCCTGCTTTACTTCTCATAAAATGTAGAAGAC
TAAAGCGGGGTTATTTGTCA

Downstream 100 bases:

>100_bases
TAGTAATATATTTTTGTATACATTTTGTATGAAAGGAAGTAAACGACGATGGATTTAAAGAATAAGACAGTAATGGTCGT
GGGAACAGGCATAAGCGGTA

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MKDNDTFGWLSTSHRKKLVLMIAAILMVCILECVRLGVIMTVKSEYYMQKADELHQRERRIKAKRGRILDRNGEILAANE
VVCTVSVIHSQIEDEDKVIKVLAGELDMDVEEVTKKVKKVSSMEYIKTNVAKDIGDAIREYDLPGVKIDEDYKRVYPYNE
LASKVLGFTGADNQGILGLEAKYDTYLSGTNGQILTLSDAGGIEIKGSREDRILPVDGQDLYTTLDVNIQKYATQLAWET
MVKKEAKQVSIIVMRPDNGEILAMANVPEYNLNSPYELNYEPDEEETQKDKMDLLNNMWRNFCINDTYEPGSIFKTVTAT
AALETGVVGLNDSFTCSGATVVSDRRIRCHKTTGHGTQDFTHTVYNSCNPAFVEWGRRVGTDNMYLYMGKLGLLAKTGID
LSGEAGTIIHKQENVGAVELATMSFGQSFQITPVQMLRAVSAIVNGGRLVTPHFGLYTGSSDGSVVNEFAYSTQDEAISS
QTSETMKKILEGVVSEGGGTKAYIDGYSIGGKTATSQKLPRGSGKYISSFIGFAPADNPQVIAMCLIDEPTGVYYGGTIA
APVVKTLYENILPYIGIERSVQLEKNDD

Sequences:

>Translated_588_residues
MKDNDTFGWLSTSHRKKLVLMIAAILMVCILECVRLGVIMTVKSEYYMQKADELHQRERRIKAKRGRILDRNGEILAANE
VVCTVSVIHSQIEDEDKVIKVLAGELDMDVEEVTKKVKKVSSMEYIKTNVAKDIGDAIREYDLPGVKIDEDYKRVYPYNE
LASKVLGFTGADNQGILGLEAKYDTYLSGTNGQILTLSDAGGIEIKGSREDRILPVDGQDLYTTLDVNIQKYATQLAWET
MVKKEAKQVSIIVMRPDNGEILAMANVPEYNLNSPYELNYEPDEEETQKDKMDLLNNMWRNFCINDTYEPGSIFKTVTAT
AALETGVVGLNDSFTCSGATVVSDRRIRCHKTTGHGTQDFTHTVYNSCNPAFVEWGRRVGTDNMYLYMGKLGLLAKTGID
LSGEAGTIIHKQENVGAVELATMSFGQSFQITPVQMLRAVSAIVNGGRLVTPHFGLYTGSSDGSVVNEFAYSTQDEAISS
QTSETMKKILEGVVSEGGGTKAYIDGYSIGGKTATSQKLPRGSGKYISSFIGFAPADNPQVIAMCLIDEPTGVYYGGTIA
APVVKTLYENILPYIGIERSVQLEKNDD
>Mature_588_residues
MKDNDTFGWLSTSHRKKLVLMIAAILMVCILECVRLGVIMTVKSEYYMQKADELHQRERRIKAKRGRILDRNGEILAANE
VVCTVSVIHSQIEDEDKVIKVLAGELDMDVEEVTKKVKKVSSMEYIKTNVAKDIGDAIREYDLPGVKIDEDYKRVYPYNE
LASKVLGFTGADNQGILGLEAKYDTYLSGTNGQILTLSDAGGIEIKGSREDRILPVDGQDLYTTLDVNIQKYATQLAWET
MVKKEAKQVSIIVMRPDNGEILAMANVPEYNLNSPYELNYEPDEEETQKDKMDLLNNMWRNFCINDTYEPGSIFKTVTAT
AALETGVVGLNDSFTCSGATVVSDRRIRCHKTTGHGTQDFTHTVYNSCNPAFVEWGRRVGTDNMYLYMGKLGLLAKTGID
LSGEAGTIIHKQENVGAVELATMSFGQSFQITPVQMLRAVSAIVNGGRLVTPHFGLYTGSSDGSVVNEFAYSTQDEAISS
QTSETMKKILEGVVSEGGGTKAYIDGYSIGGKTATSQKLPRGSGKYISSFIGFAPADNPQVIAMCLIDEPTGVYYGGTIA
APVVKTLYENILPYIGIERSVQLEKNDD

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=588, Percent_Identity=26.530612244898, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1786854, Length=618, Percent_Identity=25.0809061488673, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 64799; Mature: 64799

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNDTFGWLSTSHRKKLVLMIAAILMVCILECVRLGVIMTVKSEYYMQKADELHQRERR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHH
IKAKRGRILDRNGEILAANEVVCTVSVIHSQIEDEDKVIKVLAGELDMDVEEVTKKVKKV
HHHHCCCEECCCCCEEEECCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
SSMEYIKTNVAKDIGDAIREYDLPGVKIDEDYKRVYPYNELASKVLGFTGADNQGILGLE
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHCCHHHHHHHHHCCCCCCCCCEEEEE
AKYDTYLSGTNGQILTLSDAGGIEIKGSREDRILPVDGQDLYTTLDVNIQKYATQLAWET
CCCCCEEECCCCCEEEEECCCCEEEECCCCCCEEECCCCCEEEEEECHHHHHHHHHHHHH
MVKKEAKQVSIIVMRPDNGEILAMANVPEYNLNSPYELNYEPDEEETQKDKMDLLNNMWR
HHHHCCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
NFCINDTYEPGSIFKTVTATAALETGVVGLNDSFTCSGATVVSDRRIRCHKTTGHGTQDF
HCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCEECCEEEECCCCEEEEECCCCCCHHH
THTVYNSCNPAFVEWGRRVGTDNMYLYMGKLGLLAKTGIDLSGEAGTIIHKQENVGAVEL
HHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCCEEEEECCCCCEEEE
ATMSFGQSFQITPVQMLRAVSAIVNGGRLVTPHFGLYTGSSDGSVVNEFAYSTQDEAISS
EEECCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEECCCCCCHHHHHHHCCHHHHHHH
QTSETMKKILEGVVSEGGGTKAYIDGYSIGGKTATSQKLPRGSGKYISSFIGFAPADNPQ
HHHHHHHHHHHHHHCCCCCCEEEEECEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
VIAMCLIDEPTGVYYGGTIAAPVVKTLYENILPYIGIERSVQLEKNDD
EEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MKDNDTFGWLSTSHRKKLVLMIAAILMVCILECVRLGVIMTVKSEYYMQKADELHQRERR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHH
IKAKRGRILDRNGEILAANEVVCTVSVIHSQIEDEDKVIKVLAGELDMDVEEVTKKVKKV
HHHHCCCEECCCCCEEEECCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
SSMEYIKTNVAKDIGDAIREYDLPGVKIDEDYKRVYPYNELASKVLGFTGADNQGILGLE
HHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHCCHHHHHHHHHCCCCCCCCCEEEEE
AKYDTYLSGTNGQILTLSDAGGIEIKGSREDRILPVDGQDLYTTLDVNIQKYATQLAWET
CCCCCEEECCCCCEEEEECCCCEEEECCCCCCEEECCCCCEEEEEECHHHHHHHHHHHHH
MVKKEAKQVSIIVMRPDNGEILAMANVPEYNLNSPYELNYEPDEEETQKDKMDLLNNMWR
HHHHCCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
NFCINDTYEPGSIFKTVTATAALETGVVGLNDSFTCSGATVVSDRRIRCHKTTGHGTQDF
HCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCEECCEEEECCCCEEEEECCCCCCHHH
THTVYNSCNPAFVEWGRRVGTDNMYLYMGKLGLLAKTGIDLSGEAGTIIHKQENVGAVEL
HHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCCEEEEECCCCCEEEE
ATMSFGQSFQITPVQMLRAVSAIVNGGRLVTPHFGLYTGSSDGSVVNEFAYSTQDEAISS
EEECCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEECCCCCCHHHHHHHCCHHHHHHH
QTSETMKKILEGVVSEGGGTKAYIDGYSIGGKTATSQKLPRGSGKYISSFIGFAPADNPQ
HHHHHHHHHHHHHHCCCCCCEEEEECEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
VIAMCLIDEPTGVYYGGTIAAPVVKTLYENILPYIGIERSVQLEKNDD
EEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]