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The map label for this gene is hypB [H]

Identifier: 238916642

GI number: 238916642

Start: 704587

End: 705264

Strand: Direct

Name: hypB [H]

Synonym: EUBELI_00704

Alternate gene names: 238916642

Gene position: 704587-705264 (Clockwise)

Preceding gene: 238916641

Following gene: 238916643

Centisome position: 32.86

GC content: 39.68

Gene sequence:

>678_bases
ATGGGTAATGTAAGAGTAATTGATGTACATCAGAGTGTTTATGCAGTTAATGATGAGATAGCTGCTAAGACAAGGGCAAG
ACTTAAGGAAGAGAAAACATTTATGGTTAATCTTATGTCAAGTCCGGGAGCAGGTAAGACTACGACTCTGTTAAGAACAG
CTAAGATGTTAGGAGACAGATACCGTATAGGAGTTATGGAAGCAGATATTGATTCTTCTGTTGATGCTGAGAAGATGGCG
GCAGCAGGGATTACTTCAATTCAGGTGCATACAGGCGGAGAGTGTGCGATGGACGCTCATATGACTATGCAGGCGCTTGA
TGAATTTGATACAAAAGGTTTTGACCTTCTTGTTATGGAGAATGTCGGTAATCTAGTATGTCCGGCTGAGACAGACACAG
GAGCATCGCGTAATGTCGTTATTCTTTCGTATCCTGAGGGTGATGATAAGCCACTTAAATATCCTCTTATGTTCGAGGTG
TGTCATGTAGTTCTTATCAATAAAATTGATACTAAAGAGTATTTTGATTTTGATGACGAAGCAGTTGTTGAAAGAATTCA
CGAAAGAAATCCATTAGCAAAGGTATTTTTCGTTTCAGCTAAGACTGGCGAAGGCTTTGAAGAATGGATAAGCTGGCTTG
ACAATAATATTAAGAAATGGATTGGAGGTACAGTCTGA

Upstream 100 bases:

>100_bases
GCAGTAGTTTTCCCTATTTCTGCAAGAACAGGAGAAGGAATGGATGCATGGTGCGAATGGCTAAAAGACAATGCAGCACA
ATATTTAGGAGAGAACCAGA

Downstream 100 bases:

>100_bases
TGGTAGACAGTCGTAATTTTAAAAAACAGAATCAGAAAGGACAGGGGTTAAAGAAACATAAGTGGATTCCGCTTGTTGTT
ATCGTATTGCTTGCACTTAT

Product: hydrogenase nickel incorporation protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGNVRVIDVHQSVYAVNDEIAAKTRARLKEEKTFMVNLMSSPGAGKTTTLLRTAKMLGDRYRIGVMEADIDSSVDAEKMA
AAGITSIQVHTGGECAMDAHMTMQALDEFDTKGFDLLVMENVGNLVCPAETDTGASRNVVILSYPEGDDKPLKYPLMFEV
CHVVLINKIDTKEYFDFDDEAVVERIHERNPLAKVFFVSAKTGEGFEEWISWLDNNIKKWIGGTV

Sequences:

>Translated_225_residues
MGNVRVIDVHQSVYAVNDEIAAKTRARLKEEKTFMVNLMSSPGAGKTTTLLRTAKMLGDRYRIGVMEADIDSSVDAEKMA
AAGITSIQVHTGGECAMDAHMTMQALDEFDTKGFDLLVMENVGNLVCPAETDTGASRNVVILSYPEGDDKPLKYPLMFEV
CHVVLINKIDTKEYFDFDDEAVVERIHERNPLAKVFFVSAKTGEGFEEWISWLDNNIKKWIGGTV
>Mature_224_residues
GNVRVIDVHQSVYAVNDEIAAKTRARLKEEKTFMVNLMSSPGAGKTTTLLRTAKMLGDRYRIGVMEADIDSSVDAEKMAA
AGITSIQVHTGGECAMDAHMTMQALDEFDTKGFDLLVMENVGNLVCPAETDTGASRNVVILSYPEGDDKPLKYPLMFEVC
HVVLINKIDTKEYFDFDDEAVVERIHERNPLAKVFFVSAKTGEGFEEWISWLDNNIKKWIGGTV

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=214, Percent_Identity=40.6542056074766, Blast_Score=175, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24988; Mature: 24857

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNVRVIDVHQSVYAVNDEIAAKTRARLKEEKTFMVNLMSSPGAGKTTTLLRTAKMLGDR
CCCEEEEEECCCEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCE
YRIGVMEADIDSSVDAEKMAAAGITSIQVHTGGECAMDAHMTMQALDEFDTKGFDLLVME
EEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEEC
NVGNLVCPAETDTGASRNVVILSYPEGDDKPLKYPLMFEVCHVVLINKIDTKEYFDFDDE
CCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHH
AVVERIHERNPLAKVFFVSAKTGEGFEEWISWLDNNIKKWIGGTV
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GNVRVIDVHQSVYAVNDEIAAKTRARLKEEKTFMVNLMSSPGAGKTTTLLRTAKMLGDR
CCEEEEEECCCEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCE
YRIGVMEADIDSSVDAEKMAAAGITSIQVHTGGECAMDAHMTMQALDEFDTKGFDLLVME
EEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEEC
NVGNLVCPAETDTGASRNVVILSYPEGDDKPLKYPLMFEVCHVVLINKIDTKEYFDFDDE
CCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCHH
AVVERIHERNPLAKVFFVSAKTGEGFEEWISWLDNNIKKWIGGTV
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]