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The map label for this gene is yhdT [H]

Identifier: 238916616

GI number: 238916616

Start: 671881

End: 673164

Strand: Reverse

Name: yhdT [H]

Synonym: EUBELI_00673

Alternate gene names: 238916616

Gene position: 673164-671881 (Counterclockwise)

Preceding gene: 238916623

Following gene: 238916611

Centisome position: 31.39

GC content: 35.2

Gene sequence:

>1284_bases
TTGGATACGGATAGTATCATCCAACTTATTGCAATTGTTATTTTATTGGTTTTATCAGCATTTTTCTCATCTGCAGAGAC
TTCATTTATCACTGTGAACAGAATCAAAGTGCTGTCTTTAGTTGAAGAGGGTAATAAGAGGGCTGCTCTTGTAATTAAGA
TTATTGACCAGCCGGCAAAGATGCTCTCTGCTGTTCTTATTGGCAATAACATAGTCAATATCAGCTGTTCTGCATTAGCT
ACATCATTTACAATCAGTGTATGGGGTAATAAAGCGACAGGTATTGTTACCGGTGTTCTTACGCTTCTTGTTCTTATATT
TGGTGAGATTACACCTAAGAATACAGCCAACATGTATGCCACTAATATGGCAATGGCTTATGCTCCTATAATATGGGTGC
TTATGATTGTTCTTACACCTGTTATATTCATAGTAGACCACCTTGCAGGCTTCTTCTTATGGTTATTAAGAATTGACAAT
AACAAGAAGAAAGATATATTTACTGAGGATGAGATACGAACCATTGTTAATGTAAGCCAGCAGGAAGGTGTAATTGAATC
TAATGAAAAGAAAATCATTAATAACCTTTTTGATTTTGGTGATTCAACAGCTAAAGATGTTATGATTCCAAGGATTGATA
TGACTCTTGCTGATGTCAGCTCATCATATGATGATATAATTTCTCTGTTCAGGCAGACAATGTATACACGTATTCCTATT
TATGAGAATACACCTGATAATGTAATTGGCATTCTTAATATTAAGGATTTAATTGTCAATCCTTCTGATAACGATACATT
TAACATAAGGAACATTATCAGAAAGCCATTCTTTACATTTGAGCAGAAGAATACTTCTGACCTGTTTAAGGAAATGCAGT
TAAGTTCAACAAGCATTGCCATTGTCCTTAGTGAATATGGAACAACATCAGGAATGATTACTACCGAAGACCTGCTTGAA
GAGATTGTTGGTGAAATTCGTGATGAATATGATACTGACGAAAAGGAAGCTTTATCTAAGATTAATGATACTACATACAG
AGTTGATGGCTCATTTAAGCTTGACGATTTAAACGATGAGCTTGGTACTAAGCTCGAGTCGGAAGATAACGATTCAGTTG
GTGGACTTATCGTTGAAAGACTTGACAGACTTCCTAAAGCCGGTGATAAAATCACTGTTGGTAATGTCTGGATGTTTGTC
GAAAAGGTTGCTTCTAACAGAGCTGAATCTGTTATTGTAAAGATTATACCTGAGAAGAAAGACGAAACTAAAAAAGCTAA
TTAA

Upstream 100 bases:

>100_bases
TATGATTATCTCCTGTTTTCTTTAATAGCACTTGACGGCACAATGTGCGTACTGTAGAATGAAAAGAAATATTTTAATTT
TATGACTGGAGGGATTTTTC

Downstream 100 bases:

>100_bases
TTTTATAAAAAAAGCTGTGCATTAACATCATCTTGTTAACGCACAGCATTTTTATTATTAATACCTATTATATTACTGAT
TAAAGCGCCTTGATTCTTTC

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MDTDSIIQLIAIVILLVLSAFFSSAETSFITVNRIKVLSLVEEGNKRAALVIKIIDQPAKMLSAVLIGNNIVNISCSALA
TSFTISVWGNKATGIVTGVLTLLVLIFGEITPKNTANMYATNMAMAYAPIIWVLMIVLTPVIFIVDHLAGFFLWLLRIDN
NKKKDIFTEDEIRTIVNVSQQEGVIESNEKKIINNLFDFGDSTAKDVMIPRIDMTLADVSSSYDDIISLFRQTMYTRIPI
YENTPDNVIGILNIKDLIVNPSDNDTFNIRNIIRKPFFTFEQKNTSDLFKEMQLSSTSIAIVLSEYGTTSGMITTEDLLE
EIVGEIRDEYDTDEKEALSKINDTTYRVDGSFKLDDLNDELGTKLESEDNDSVGGLIVERLDRLPKAGDKITVGNVWMFV
EKVASNRAESVIVKIIPEKKDETKKAN

Sequences:

>Translated_427_residues
MDTDSIIQLIAIVILLVLSAFFSSAETSFITVNRIKVLSLVEEGNKRAALVIKIIDQPAKMLSAVLIGNNIVNISCSALA
TSFTISVWGNKATGIVTGVLTLLVLIFGEITPKNTANMYATNMAMAYAPIIWVLMIVLTPVIFIVDHLAGFFLWLLRIDN
NKKKDIFTEDEIRTIVNVSQQEGVIESNEKKIINNLFDFGDSTAKDVMIPRIDMTLADVSSSYDDIISLFRQTMYTRIPI
YENTPDNVIGILNIKDLIVNPSDNDTFNIRNIIRKPFFTFEQKNTSDLFKEMQLSSTSIAIVLSEYGTTSGMITTEDLLE
EIVGEIRDEYDTDEKEALSKINDTTYRVDGSFKLDDLNDELGTKLESEDNDSVGGLIVERLDRLPKAGDKITVGNVWMFV
EKVASNRAESVIVKIIPEKKDETKKAN
>Mature_427_residues
MDTDSIIQLIAIVILLVLSAFFSSAETSFITVNRIKVLSLVEEGNKRAALVIKIIDQPAKMLSAVLIGNNIVNISCSALA
TSFTISVWGNKATGIVTGVLTLLVLIFGEITPKNTANMYATNMAMAYAPIIWVLMIVLTPVIFIVDHLAGFFLWLLRIDN
NKKKDIFTEDEIRTIVNVSQQEGVIESNEKKIINNLFDFGDSTAKDVMIPRIDMTLADVSSSYDDIISLFRQTMYTRIPI
YENTPDNVIGILNIKDLIVNPSDNDTFNIRNIIRKPFFTFEQKNTSDLFKEMQLSSTSIAIVLSEYGTTSGMITTEDLLE
EIVGEIRDEYDTDEKEALSKINDTTYRVDGSFKLDDLNDELGTKLESEDNDSVGGLIVERLDRLPKAGDKITVGNVWMFV
EKVASNRAESVIVKIIPEKKDETKKAN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=384, Percent_Identity=28.90625, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI94681046, Length=343, Percent_Identity=24.198250728863, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI40068055, Length=343, Percent_Identity=24.198250728863, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI40068053, Length=343, Percent_Identity=24.198250728863, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI145693175, Length=408, Percent_Identity=28.4313725490196, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1786879, Length=277, Percent_Identity=29.6028880866426, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=22.0689655172414, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082033, Length=270, Percent_Identity=23.7037037037037, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788119, Length=242, Percent_Identity=24.3801652892562, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539402, Length=346, Percent_Identity=23.9884393063584, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324512, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47636; Mature: 47636

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDSIIQLIAIVILLVLSAFFSSAETSFITVNRIKVLSLVEEGNKRAALVIKIIDQPAK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEECCCHHH
MLSAVLIGNNIVNISCSALATSFTISVWGNKATGIVTGVLTLLVLIFGEITPKNTANMYA
HHHHHHHCCCEEEEEHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TNMAMAYAPIIWVLMIVLTPVIFIVDHLAGFFLWLLRIDNNKKKDIFTEDEIRTIVNVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHH
QEGVIESNEKKIINNLFDFGDSTAKDVMIPRIDMTLADVSSSYDDIISLFRQTMYTRIPI
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
YENTPDNVIGILNIKDLIVNPSDNDTFNIRNIIRKPFFTFEQKNTSDLFKEMQLSSTSIA
CCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCEEE
IVLSEYGTTSGMITTEDLLEEIVGEIRDEYDTDEKEALSKINDTTYRVDGSFKLDDLNDE
EEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEECCCCHH
LGTKLESEDNDSVGGLIVERLDRLPKAGDKITVGNVWMFVEKVASNRAESVIVKIIPEKK
HCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCHHEEEEEECCCCC
DETKKAN
CCCCCCC
>Mature Secondary Structure
MDTDSIIQLIAIVILLVLSAFFSSAETSFITVNRIKVLSLVEEGNKRAALVIKIIDQPAK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCEEEEEEECCCHHH
MLSAVLIGNNIVNISCSALATSFTISVWGNKATGIVTGVLTLLVLIFGEITPKNTANMYA
HHHHHHHCCCEEEEEHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TNMAMAYAPIIWVLMIVLTPVIFIVDHLAGFFLWLLRIDNNKKKDIFTEDEIRTIVNVSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHH
QEGVIESNEKKIINNLFDFGDSTAKDVMIPRIDMTLADVSSSYDDIISLFRQTMYTRIPI
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
YENTPDNVIGILNIKDLIVNPSDNDTFNIRNIIRKPFFTFEQKNTSDLFKEMQLSSTSIA
CCCCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCEEE
IVLSEYGTTSGMITTEDLLEEIVGEIRDEYDTDEKEALSKINDTTYRVDGSFKLDDLNDE
EEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEECCCCHH
LGTKLESEDNDSVGGLIVERLDRLPKAGDKITVGNVWMFVEKVASNRAESVIVKIIPEKK
HCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCHHEEEEEECCCCC
DETKKAN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]