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The map label for this gene is glnA [H]

Identifier: 238916377

GI number: 238916377

Start: 444076

End: 445410

Strand: Direct

Name: glnA [H]

Synonym: EUBELI_00431

Alternate gene names: 238916377

Gene position: 444076-445410 (Clockwise)

Preceding gene: 238916372

Following gene: 238916378

Centisome position: 20.71

GC content: 38.95

Gene sequence:

>1335_bases
ATGAGCAGATACACTAAGGACGATATATTCAGAATGGTTGAAGAAGAGGATGTAGAGTTTATACGTCTTCAGTTTACAGA
TATTTTTGGAACACTCAAGAATATTGCAATTACTTCAAGCCAGCTTGAGAAGGCACTTGATAACAAATGCATGTTTGACG
GTTCTTCTGTTGAAGGCTTTGTAAGAATTGAAGAGTCAGATATGTATCTGTATCCTGACTACGATACATTTGAAATATTC
CCATGGAGACCACAGCAGGGAAAGGTTGCAAGACTTATCTGTGATGTGTATACACCAGATGGCAAGCCTTTTGAGGGCGA
CCCAAGATGGATACTTAAGAAAACTATTAAAGAAGCGAATGAAATGGGATACCGCTTTGATGTCGGTCCAGAATGTGAAT
TTTTCTTATTCCATACAGATGACAACGGACTTCCTACAACTTTAAGCCATGAAAAAGCTGGATATTTTGATCTTGGACCT
AATGACCTGGGCGAGAATATAAGAAGAGATATGGTTCTTACTCTTGAGGATATGGGGTTTGAGATTGAGGCTTCACATCA
TGAGGTTGCTCCTGCACAGCATGAGATTGATTTTAAATATGATGAGGCTTTAAAGACAGCAGATAATATACAGACATTTA
AGATGACAGTTAAGACAATTGCCAAGAGACATGGACTTTATGCAACATTTATGCCAAAGCCAAAGTTTGGTATCAGCGGT
TCTGGAATGCATATTAATATGTCACTTGCAACTGAAGAGGGTAAGAATATATTTGCAGATGAGAATGGAAAGATTGGTTT
ATCAGATGATGCATATCATTTTATTGCTGGTATTATGAAGCACGCAAGAGGTATGTCAGCAATAACTAATCCGCTTGTTA
ATTCATATAAAAGACTTGTTCCGGGATATGAAGCACCTGTATATATAGCATGGTCAGCAAAGAACAGAAGTCCGCTTATA
AGAATACCTGCATCAAGAGGAAATGGAACAAGAGTTGAGTTAAGAAATCCGGATCCTACAGCTAATCCATATCTCGTGCT
GGCACTCTGCCTTGCAGCAGGACTTGATGGTATTAAGAACAAGATAGAAGTACCTGAGAGTGTTGACTGCAATATATATG
AGATGACACCTGGCGAGAGAAGGGCAGCAGGAATAGAGAATATGCCGGCAGACCTTAAGGAAGCTGTTGACTGTCTTGTG
ACAGACGAATTTTTATGCAGCGTACTTGGAGAACATATTACAACCAAATATGTTGAAGCTAAGATGAAAGAATGGGAAAA
CTACACAACAAGGGTCTCACAGTGGGAAATTGATGAATATCTCTACAAGTATTGA

Upstream 100 bases:

>100_bases
AAATATTAGTATTCTACACAAAGAGATTAAAATGTAGTATATTTATAAAAGTTGGCAATAAGCCACAATAAGAAATATAT
AATTATAACGGAGGTTTCTT

Downstream 100 bases:

>100_bases
TTAAACATGGTAAAGCGTATGCTAAGTAGAAAAGGAGTTAATTGATGTCCACATTGATTGTAGCATTTCCTAAGTTAGAG
GAGGCTAAAACAGTAAGGAA

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSRYTKDDIFRMVEEEDVEFIRLQFTDIFGTLKNIAITSSQLEKALDNKCMFDGSSVEGFVRIEESDMYLYPDYDTFEIF
PWRPQQGKVARLICDVYTPDGKPFEGDPRWILKKTIKEANEMGYRFDVGPECEFFLFHTDDNGLPTTLSHEKAGYFDLGP
NDLGENIRRDMVLTLEDMGFEIEASHHEVAPAQHEIDFKYDEALKTADNIQTFKMTVKTIAKRHGLYATFMPKPKFGISG
SGMHINMSLATEEGKNIFADENGKIGLSDDAYHFIAGIMKHARGMSAITNPLVNSYKRLVPGYEAPVYIAWSAKNRSPLI
RIPASRGNGTRVELRNPDPTANPYLVLALCLAAGLDGIKNKIEVPESVDCNIYEMTPGERRAAGIENMPADLKEAVDCLV
TDEFLCSVLGEHITTKYVEAKMKEWENYTTRVSQWEIDEYLYKY

Sequences:

>Translated_444_residues
MSRYTKDDIFRMVEEEDVEFIRLQFTDIFGTLKNIAITSSQLEKALDNKCMFDGSSVEGFVRIEESDMYLYPDYDTFEIF
PWRPQQGKVARLICDVYTPDGKPFEGDPRWILKKTIKEANEMGYRFDVGPECEFFLFHTDDNGLPTTLSHEKAGYFDLGP
NDLGENIRRDMVLTLEDMGFEIEASHHEVAPAQHEIDFKYDEALKTADNIQTFKMTVKTIAKRHGLYATFMPKPKFGISG
SGMHINMSLATEEGKNIFADENGKIGLSDDAYHFIAGIMKHARGMSAITNPLVNSYKRLVPGYEAPVYIAWSAKNRSPLI
RIPASRGNGTRVELRNPDPTANPYLVLALCLAAGLDGIKNKIEVPESVDCNIYEMTPGERRAAGIENMPADLKEAVDCLV
TDEFLCSVLGEHITTKYVEAKMKEWENYTTRVSQWEIDEYLYKY
>Mature_443_residues
SRYTKDDIFRMVEEEDVEFIRLQFTDIFGTLKNIAITSSQLEKALDNKCMFDGSSVEGFVRIEESDMYLYPDYDTFEIFP
WRPQQGKVARLICDVYTPDGKPFEGDPRWILKKTIKEANEMGYRFDVGPECEFFLFHTDDNGLPTTLSHEKAGYFDLGPN
DLGENIRRDMVLTLEDMGFEIEASHHEVAPAQHEIDFKYDEALKTADNIQTFKMTVKTIAKRHGLYATFMPKPKFGISGS
GMHINMSLATEEGKNIFADENGKIGLSDDAYHFIAGIMKHARGMSAITNPLVNSYKRLVPGYEAPVYIAWSAKNRSPLIR
IPASRGNGTRVELRNPDPTANPYLVLALCLAAGLDGIKNKIEVPESVDCNIYEMTPGERRAAGIENMPADLKEAVDCLVT
DEFLCSVLGEHITTKYVEAKMKEWENYTTRVSQWEIDEYLYKY

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=438, Percent_Identity=27.8538812785388, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1790301, Length=473, Percent_Identity=39.7463002114165, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI87081870, Length=453, Percent_Identity=26.2693156732892, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360453, Length=349, Percent_Identity=26.647564469914, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136208, Length=349, Percent_Identity=26.647564469914, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580558, Length=349, Percent_Identity=26.647564469914, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50496; Mature: 50365

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00180 GLNA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYTKDDIFRMVEEEDVEFIRLQFTDIFGTLKNIAITSSQLEKALDNKCMFDGSSVEGF
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHEECHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDYDTFEIFPWRPQQGKVARLICDVYTPDGKPFEGDPRWILKKTIKEAN
EEEECCCEEEECCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
EMGYRFDVGPECEFFLFHTDDNGLPTTLSHEKAGYFDLGPNDLGENIRRDMVLTLEDMGF
HCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCEEEEEECCCE
EIEASHHEVAPAQHEIDFKYDEALKTADNIQTFKMTVKTIAKRHGLYATFMPKPKFGISG
EEECCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SGMHINMSLATEEGKNIFADENGKIGLSDDAYHFIAGIMKHARGMSAITNPLVNSYKRLV
CCEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
PGYEAPVYIAWSAKNRSPLIRIPASRGNGTRVELRNPDPTANPYLVLALCLAAGLDGIKN
CCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHH
KIEVPESVDCNIYEMTPGERRAAGIENMPADLKEAVDCLVTDEFLCSVLGEHITTKYVEA
CCCCCCCCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMKEWENYTTRVSQWEIDEYLYKY
HHHHHHHHHHHCHHEEHHHHHHCC
>Mature Secondary Structure 
SRYTKDDIFRMVEEEDVEFIRLQFTDIFGTLKNIAITSSQLEKALDNKCMFDGSSVEGF
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHEECHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDYDTFEIFPWRPQQGKVARLICDVYTPDGKPFEGDPRWILKKTIKEAN
EEEECCCEEEECCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
EMGYRFDVGPECEFFLFHTDDNGLPTTLSHEKAGYFDLGPNDLGENIRRDMVLTLEDMGF
HCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCEEEEEECCCE
EIEASHHEVAPAQHEIDFKYDEALKTADNIQTFKMTVKTIAKRHGLYATFMPKPKFGISG
EEECCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SGMHINMSLATEEGKNIFADENGKIGLSDDAYHFIAGIMKHARGMSAITNPLVNSYKRLV
CCEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
PGYEAPVYIAWSAKNRSPLIRIPASRGNGTRVELRNPDPTANPYLVLALCLAAGLDGIKN
CCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHH
KIEVPESVDCNIYEMTPGERRAAGIENMPADLKEAVDCLVTDEFLCSVLGEHITTKYVEA
CCCCCCCCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMKEWENYTTRVSQWEIDEYLYKY
HHHHHHHHHHHCHHEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2891680; 1981087 [H]