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The map label for this gene is gcp [H]

Identifier: 238916346

GI number: 238916346

Start: 409932

End: 410990

Strand: Direct

Name: gcp [H]

Synonym: EUBELI_00380

Alternate gene names: 238916346

Gene position: 409932-410990 (Clockwise)

Preceding gene: 238916345

Following gene: 238916347

Centisome position: 19.12

GC content: 41.45

Gene sequence:

>1059_bases
GTGATTCAGAACAATAGGAGATATAAAATGAGCGAAAAAGATGATGTTCTTATCCTTGCAATAGAAAGTTCATGTGATGA
GACAGCGGCAGCAGTAGTGAAGAATGGAAGAGAGGTATTGTCAAATGTGATTAATACCCAGATAGCCATACATACAGAGT
ATGGTGGTGTAGTTCCTGAAATTGCGTCAAGAAAACATATAGAAAATATTAACCCTGTAATAAGGAAAGCACTTGAAGAT
GCAGGAGTAACACTTGATGATATAGATGCAATAGGCGTTACATATGGTCCTGGACTTGTAGGTGCGCTTCTTGTCGGAGT
TGCGGAGGCTAAAGCAATAGCATTTGCAAAGAATAAACCATTAGTAGGAGTGCATCACATAGAAGGCCATATTAGTGCCA
ACTATGTTGAGAATAAAGAACTCGAACCTCCTTTTGTTGCACTTGTTGTTTCGGGAGGACATACACACCTTGTTAAGGTC
AATGACTATGGCGAGTATGAAATAGTTGGAAGAACAAGAGATGATGCGGCAGGAGAAGCATTTGACAAGGTTGCAAGGGC
AATAGGATTGGGATATCCGGGAGGACCTAAGATAGATAAGCTTGCAAAGGAAGGCAATCCGGATGCAATAGAATTTCCGA
GGGCACATGTTGATGATGCTCCTTATGATTTTTCGTTTAGTGGAATAAAGTCAGCAGTGCTTAATTATATTAATTCTGCC
AATATGCAGGGCAAAGAGATAAACAGGGCTGATGTAGCAGCGTCATTCCAGAAGGCGGTAGTAGATGCTCTTGTTTCACG
GGCAGTAAGGCTGGCAAAAGAATGTGGAATGGATAAGCTTGCAATAGCTGGAGGAGTTGCATCTAATTCTGCGCTTCGTG
CAGCAATACAGGAAGCGTGTGCAAAGAATAACATTGGCTTCTATTCGCCATCACCTATACTATGTACAGACAACGCAGCT
ATGATAGGGGCAGCAGCATATTATGAATATATTAAGGGGGTACGTCATGGCTATGATTTAAATGCTGTGCCGAACCTTAA
ATTAGGAGAACGCATATAA

Upstream 100 bases:

>100_bases
CAGGGTGACAAGCTTATAGATTCACCAACAAAATTCACCTTAAGAAAAGATGATGATGGACACTGGAAGATTCTTTTCTG
GGAGCTTACTGAAATAAGCA

Downstream 100 bases:

>100_bases
TGAATACGGCTATAGTTCTTGCGGGTGGAAGTGGAAAAAGAATGCATAGTGAAATTCCAAAGCAGTATATGCAGCTTAAT
GGAAAGCCTGTTATATATTA

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MIQNNRRYKMSEKDDVLILAIESSCDETAAAVVKNGREVLSNVINTQIAIHTEYGGVVPEIASRKHIENINPVIRKALED
AGVTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAFAKNKPLVGVHHIEGHISANYVENKELEPPFVALVVSGGHTHLVKV
NDYGEYEIVGRTRDDAAGEAFDKVARAIGLGYPGGPKIDKLAKEGNPDAIEFPRAHVDDAPYDFSFSGIKSAVLNYINSA
NMQGKEINRADVAASFQKAVVDALVSRAVRLAKECGMDKLAIAGGVASNSALRAAIQEACAKNNIGFYSPSPILCTDNAA
MIGAAAYYEYIKGVRHGYDLNAVPNLKLGERI

Sequences:

>Translated_352_residues
MIQNNRRYKMSEKDDVLILAIESSCDETAAAVVKNGREVLSNVINTQIAIHTEYGGVVPEIASRKHIENINPVIRKALED
AGVTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAFAKNKPLVGVHHIEGHISANYVENKELEPPFVALVVSGGHTHLVKV
NDYGEYEIVGRTRDDAAGEAFDKVARAIGLGYPGGPKIDKLAKEGNPDAIEFPRAHVDDAPYDFSFSGIKSAVLNYINSA
NMQGKEINRADVAASFQKAVVDALVSRAVRLAKECGMDKLAIAGGVASNSALRAAIQEACAKNNIGFYSPSPILCTDNAA
MIGAAAYYEYIKGVRHGYDLNAVPNLKLGERI
>Mature_352_residues
MIQNNRRYKMSEKDDVLILAIESSCDETAAAVVKNGREVLSNVINTQIAIHTEYGGVVPEIASRKHIENINPVIRKALED
AGVTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAFAKNKPLVGVHHIEGHISANYVENKELEPPFVALVVSGGHTHLVKV
NDYGEYEIVGRTRDDAAGEAFDKVARAIGLGYPGGPKIDKLAKEGNPDAIEFPRAHVDDAPYDFSFSGIKSAVLNYINSA
NMQGKEINRADVAASFQKAVVDALVSRAVRLAKECGMDKLAIAGGVASNSALRAAIQEACAKNNIGFYSPSPILCTDNAA
MIGAAAYYEYIKGVRHGYDLNAVPNLKLGERI

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=364, Percent_Identity=32.967032967033, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI8923380, Length=322, Percent_Identity=32.9192546583851, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=43.8438438438438, Blast_Score=292, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17557464, Length=321, Percent_Identity=33.6448598130841, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=332, Percent_Identity=28.6144578313253, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=361, Percent_Identity=32.409972299169, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=318, Percent_Identity=28.9308176100629, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20129063, Length=351, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21357207, Length=336, Percent_Identity=30.952380952381, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37539; Mature: 37539

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQNNRRYKMSEKDDVLILAIESSCDETAAAVVKNGREVLSNVINTQIAIHTEYGGVVPE
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHCCEEEEEECCCCCCHH
IASRKHIENINPVIRKALEDAGVTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAFAKNKP
HHHHHHHHHCCHHHHHHHHHCCCCHHCCCCCCEECCHHHHHHHHHHHHHHHHEEEECCCC
LVGVHHIEGHISANYVENKELEPPFVALVVSGGHTHLVKVNDYGEYEIVGRTRDDAAGEA
EEEEEEECCCEEECEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEECCCCCHHHHH
FDKVARAIGLGYPGGPKIDKLAKEGNPDAIEFPRAHVDDAPYDFSFSGIKSAVLNYINSA
HHHHHHHHHCCCCCCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NMQGKEINRADVAASFQKAVVDALVSRAVRLAKECGMDKLAIAGGVASNSALRAAIQEAC
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCCCCCCHHHHHHHHHHH
AKNNIGFYSPSPILCTDNAAMIGAAAYYEYIKGVRHGYDLNAVPNLKLGERI
HHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIQNNRRYKMSEKDDVLILAIESSCDETAAAVVKNGREVLSNVINTQIAIHTEYGGVVPE
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHCCEEEEEECCCCCCHH
IASRKHIENINPVIRKALEDAGVTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAFAKNKP
HHHHHHHHHCCHHHHHHHHHCCCCHHCCCCCCEECCHHHHHHHHHHHHHHHHEEEECCCC
LVGVHHIEGHISANYVENKELEPPFVALVVSGGHTHLVKVNDYGEYEIVGRTRDDAAGEA
EEEEEEECCCEEECEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEECCCCCHHHHH
FDKVARAIGLGYPGGPKIDKLAKEGNPDAIEFPRAHVDDAPYDFSFSGIKSAVLNYINSA
HHHHHHHHHCCCCCCCCHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NMQGKEINRADVAASFQKAVVDALVSRAVRLAKECGMDKLAIAGGVASNSALRAAIQEAC
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCCCCCCHHHHHHHHHHH
AKNNIGFYSPSPILCTDNAAMIGAAAYYEYIKGVRHGYDLNAVPNLKLGERI
HHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA