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The map label for this gene is yfkJ [H]

Identifier: 238916185

GI number: 238916185

Start: 247505

End: 247915

Strand: Direct

Name: yfkJ [H]

Synonym: EUBELI_00219

Alternate gene names: 238916185

Gene position: 247505-247915 (Clockwise)

Preceding gene: 238916184

Following gene: 238916187

Centisome position: 11.54

GC content: 45.26

Gene sequence:

>411_bases
ATGGCAGAAAGCGTTATGACATATTTAGTTGAGAAAGAGGGACTTGCTGATAAGTTCTATATTAATTCAGCGGCGACAAG
CCGCGAGGAAATTGGTAATGGAGTGCATCATGGCACTGTTGCCAAGTTGAAGAAAGAAGGGATTCCGGTGATTCCCCACA
GGGCAGTGCAGATGACTCTGAATGATTATGAGGAATATGATTACCTTATTGGAATGGATACTGAGAATATCCGCAATATG
CAGAGGATATCGGACGGAGATCCGGATGAGAAGATATATAAGCTGCTTACTTTTGCGGGGAGTGGGCTTGATGTGGCAGA
CCCATGGTATACGGGAGATTTTGAGGCAACCTACAGGGACGTTCTGGCAGGTTGCAAAGGGTTGCTTGAATGCCTTAAGG
AAGAATTGTAG

Upstream 100 bases:

>100_bases
CGAAAAGCCTTTAAATACAAGGAAAAGTGAAAATTTAAGGAGATATAAAAATATGATAAAAGTACTATTCATCTGCCACG
GCAACATCTGCCGAAGCACT

Downstream 100 bases:

>100_bases
GCGGCTACAGGTAGGTTGTATGAGCAAGTGCCACGGCAATATATGTGAATAAAAAGGGTCGGGCAAGGCAGGCTGTCTTC
AACGGGGACAGCCTGCCTTG

Product: protein-tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MAESVMTYLVEKEGLADKFYINSAATSREEIGNGVHHGTVAKLKKEGIPVIPHRAVQMTLNDYEEYDYLIGMDTENIRNM
QRISDGDPDEKIYKLLTFAGSGLDVADPWYTGDFEATYRDVLAGCKGLLECLKEEL

Sequences:

>Translated_136_residues
MAESVMTYLVEKEGLADKFYINSAATSREEIGNGVHHGTVAKLKKEGIPVIPHRAVQMTLNDYEEYDYLIGMDTENIRNM
QRISDGDPDEKIYKLLTFAGSGLDVADPWYTGDFEATYRDVLAGCKGLLECLKEEL
>Mature_135_residues
AESVMTYLVEKEGLADKFYINSAATSREEIGNGVHHGTVAKLKKEGIPVIPHRAVQMTLNDYEEYDYLIGMDTENIRNMQ
RISDGDPDEKIYKLLTFAGSGLDVADPWYTGDFEATYRDVLAGCKGLLECLKEEL

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=135, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325330, Length=140, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15257; Mature: 15126

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESVMTYLVEKEGLADKFYINSAATSREEIGNGVHHGTVAKLKKEGIPVIPHRAVQMTL
CCHHHHHHHHHHCCCCCCEEECCHHCCHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
NDYEEYDYLIGMDTENIRNMQRISDGDPDEKIYKLLTFAGSGLDVADPWYTGDFEATYRD
HHHHHCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
VLAGCKGLLECLKEEL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AESVMTYLVEKEGLADKFYINSAATSREEIGNGVHHGTVAKLKKEGIPVIPHRAVQMTL
CHHHHHHHHHHCCCCCCEEECCHHCCHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
NDYEEYDYLIGMDTENIRNMQRISDGDPDEKIYKLLTFAGSGLDVADPWYTGDFEATYRD
HHHHHCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
VLAGCKGLLECLKEEL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]