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The map label for this gene is 238916150

Identifier: 238916150

GI number: 238916150

Start: 214123

End: 215493

Strand: Direct

Name: 238916150

Synonym: EUBELI_00184

Alternate gene names: NA

Gene position: 214123-215493 (Clockwise)

Preceding gene: 238916149

Following gene: 238916151

Centisome position: 9.99

GC content: 40.85

Gene sequence:

>1371_bases
ATGAGGAAGAAAGGAACTAAAGCTATGGGAAATAACGGAATTGAATTGGAAAGAGATGGCTTTAAGAGCCGTACAGGTTT
TATTCTTGCCTGTATCGGTTCGGCAGTAGGAATGGGAAATATATGGCGTTTTCCATATATGGTATCTGCATGGGGTGGTA
TGACATTTTTAATACCTTATGTATTATTTGTAATATTGATAGGTTCAACAGGTGTTATCGAGGAGATGGCACTTGGCCGT
GCGACTAAGGGCGGACCTATTAAAGCATTTGGCGACTGTATGCAGATGCGTACAGGAAAGAGAAAAGCAGGTGAGGCAAT
TGGTTTTATTCCTGTGCTTGGCTCACTGGCTCTGGCAATGGGCTATACTGTAGTTGTTGGCTGGATATTCAAATATACTT
ATCTTGCATTTTCTGGAAAGCTTTCAGCAATGGGCAATGATATGTCAGCTATTGGTGGTATGTTTGGAAGTACAGCAAGC
ACATTTGGAAATAATATGTGGCTTATAATCGCAATGGTTGTAACTGCTGTTATTATGGCACTTGGTATTGCAGGCGGAAT
TGAGAAAGCAAACAAGGTCATGATGCCTTTGCTTTTCATCATGTTTGTAGGTCTTGGAATATACATTTTCACACTTCCAG
GTTCAAGTGCAGGTTATAAATACATATTTACACTTAACCCTAAGGAACTTCTTGATATAAAGCTCTGGATATATGCATTT
GGTCAGGCGTTCTTCTCACTGTCTATCGCAGGTAACGGAACTGTTATCTATGGTTCATATCTTAGTGATAAGGAAAATAT
TGTTTCTTCTGCAAGAAATGTTGCAGTATTTGATACTATTGCTGCTTTATTAGCTGCATTTGTTATTATTCCTGGTATGG
CAGCAGGCGGTGCCGAGTTATCATCAGGTGGTCCCGGACTGATGTTTATCTATCTTGTAAATGTATTTAATGGTATGCCG
GGTGGCAAGATTGTAGGAATTGTATTCTATGTATGTGTTCTGTTTGCAGGTATGAGCTCACTTGTTAATCTGTATGAAGC
TCCGGTTGCAACTATTCAGGAGAAGCTTAAGCTTAACCGTGTTGCATCTGTTGGAATTATCGCAGTGGCTGGCTGTGTTG
TGTCACTTGTAATACAGGGTATTGTATCAGGCTGGATGGACGCAGTATCTATCTATATCTGCCCACTTGGCGCAATGCTC
GCAGCAATTATGTTCTTCTGGGTTGAAGGAAAGAAGTTTGCTGTTGATGCTGTTAATGCAGGTGCAGATAAGCCTATTGG
AAAGTGGTTTGTACCACTTGGCAAATATGTCCTTGTTCCACTTGCACTTGTTGCACTTATTGCAGGTGCTTTACTTGGTG
GAATTGGCTGA

Upstream 100 bases:

>100_bases
CAAAGGAGCCATGACCCGGAAGGGGTAATGGTTTCTTTGCCTTTTTTGCGTATAAGATATCTTTGCAGGAAAATGTATAG
CGAATACGGCTATTCATAAT

Downstream 100 bases:

>100_bases
TGGAGGATTGGACTGGTTGATTGAGACTGGCGGATTGCTTTGCAATCCGCCTTTTTTGCGTGGTGGGGAGCGGGAGCGTG
GCGGAATTGACCTTGAGGCG

Product: neurotransmitter:Na+ symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MRKKGTKAMGNNGIELERDGFKSRTGFILACIGSAVGMGNIWRFPYMVSAWGGMTFLIPYVLFVILIGSTGVIEEMALGR
ATKGGPIKAFGDCMQMRTGKRKAGEAIGFIPVLGSLALAMGYTVVVGWIFKYTYLAFSGKLSAMGNDMSAIGGMFGSTAS
TFGNNMWLIIAMVVTAVIMALGIAGGIEKANKVMMPLLFIMFVGLGIYIFTLPGSSAGYKYIFTLNPKELLDIKLWIYAF
GQAFFSLSIAGNGTVIYGSYLSDKENIVSSARNVAVFDTIAALLAAFVIIPGMAAGGAELSSGGPGLMFIYLVNVFNGMP
GGKIVGIVFYVCVLFAGMSSLVNLYEAPVATIQEKLKLNRVASVGIIAVAGCVVSLVIQGIVSGWMDAVSIYICPLGAML
AAIMFFWVEGKKFAVDAVNAGADKPIGKWFVPLGKYVLVPLALVALIAGALLGGIG

Sequences:

>Translated_456_residues
MRKKGTKAMGNNGIELERDGFKSRTGFILACIGSAVGMGNIWRFPYMVSAWGGMTFLIPYVLFVILIGSTGVIEEMALGR
ATKGGPIKAFGDCMQMRTGKRKAGEAIGFIPVLGSLALAMGYTVVVGWIFKYTYLAFSGKLSAMGNDMSAIGGMFGSTAS
TFGNNMWLIIAMVVTAVIMALGIAGGIEKANKVMMPLLFIMFVGLGIYIFTLPGSSAGYKYIFTLNPKELLDIKLWIYAF
GQAFFSLSIAGNGTVIYGSYLSDKENIVSSARNVAVFDTIAALLAAFVIIPGMAAGGAELSSGGPGLMFIYLVNVFNGMP
GGKIVGIVFYVCVLFAGMSSLVNLYEAPVATIQEKLKLNRVASVGIIAVAGCVVSLVIQGIVSGWMDAVSIYICPLGAML
AAIMFFWVEGKKFAVDAVNAGADKPIGKWFVPLGKYVLVPLALVALIAGALLGGIG
>Mature_456_residues
MRKKGTKAMGNNGIELERDGFKSRTGFILACIGSAVGMGNIWRFPYMVSAWGGMTFLIPYVLFVILIGSTGVIEEMALGR
ATKGGPIKAFGDCMQMRTGKRKAGEAIGFIPVLGSLALAMGYTVVVGWIFKYTYLAFSGKLSAMGNDMSAIGGMFGSTAS
TFGNNMWLIIAMVVTAVIMALGIAGGIEKANKVMMPLLFIMFVGLGIYIFTLPGSSAGYKYIFTLNPKELLDIKLWIYAF
GQAFFSLSIAGNGTVIYGSYLSDKENIVSSARNVAVFDTIAALLAAFVIIPGMAAGGAELSSGGPGLMFIYLVNVFNGMP
GGKIVGIVFYVCVLFAGMSSLVNLYEAPVATIQEKLKLNRVASVGIIAVAGCVVSLVIQGIVSGWMDAVSIYICPLGAML
AAIMFFWVEGKKFAVDAVNAGADKPIGKWFVPLGKYVLVPLALVALIAGALLGGIG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI194018524, Length=298, Percent_Identity=27.5167785234899, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI188528618, Length=401, Percent_Identity=26.6832917705736, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI4507041, Length=392, Percent_Identity=22.9591836734694, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI289191377, Length=400, Percent_Identity=24.75, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI289191351, Length=400, Percent_Identity=24.75, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4557046, Length=400, Percent_Identity=24.75, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI51468073, Length=333, Percent_Identity=22.5225225225225, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI58219014, Length=310, Percent_Identity=26.4516129032258, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI33354281, Length=318, Percent_Identity=24.8427672955975, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI11181770, Length=300, Percent_Identity=26.3333333333333, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI21361581, Length=371, Percent_Identity=24.7978436657682, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI7657587, Length=398, Percent_Identity=25.1256281407035, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI134304856, Length=355, Percent_Identity=25.6338028169014, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI4507043, Length=415, Percent_Identity=23.6144578313253, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI92859670, Length=436, Percent_Identity=23.1651376146789, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI12408638, Length=279, Percent_Identity=26.1648745519713, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI171184408, Length=383, Percent_Identity=24.2819843342037, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184406, Length=383, Percent_Identity=24.2819843342037, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184404, Length=383, Percent_Identity=24.2819843342037, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI197276623, Length=366, Percent_Identity=24.5901639344262, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI54607094, Length=366, Percent_Identity=24.5901639344262, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI5032097, Length=354, Percent_Identity=25.9887005649718, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI21361693, Length=141, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI218563756, Length=351, Percent_Identity=26.2108262108262, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI6005715, Length=133, Percent_Identity=30.0751879699248, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=413, Percent_Identity=24.6973365617433, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17554804, Length=408, Percent_Identity=26.9607843137255, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI133952791, Length=445, Percent_Identity=24.2696629213483, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17535731, Length=118, Percent_Identity=36.4406779661017, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17136952, Length=418, Percent_Identity=23.9234449760766, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364394, Length=383, Percent_Identity=24.2819843342037, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28574704, Length=383, Percent_Identity=24.2819843342037, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136950, Length=383, Percent_Identity=24.2819843342037, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28574702, Length=383, Percent_Identity=24.2819843342037, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24654186, Length=437, Percent_Identity=24.9427917620137, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24655079, Length=315, Percent_Identity=25.7142857142857, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24661428, Length=437, Percent_Identity=27.0022883295195, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24762620, Length=382, Percent_Identity=26.7015706806283, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281365034, Length=396, Percent_Identity=24.4949494949495, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19921936, Length=391, Percent_Identity=25.0639386189258, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24652942, Length=383, Percent_Identity=25.5874673629243, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45551088, Length=383, Percent_Identity=25.5874673629243, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221329674, Length=420, Percent_Identity=23.8095238095238, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639514, Length=420, Percent_Identity=23.8095238095238, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24582567, Length=487, Percent_Identity=24.0246406570842, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363702, Length=376, Percent_Identity=26.3297872340426, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24639516, Length=440, Percent_Identity=22.7272727272727, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551183, Length=425, Percent_Identity=23.5294117647059, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364136, Length=410, Percent_Identity=23.6585365853659, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363700, Length=322, Percent_Identity=27.9503105590062, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550877, Length=425, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48007; Mature: 48007

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKGTKAMGNNGIELERDGFKSRTGFILACIGSAVGMGNIWRFPYMVSAWGGMTFLIPY
CCCCCCCCCCCCCCEECCCCCCCCCCEEEEEHHHHCCCCCCCCCCHHHHHHCCHHHHHHH
VLFVILIGSTGVIEEMALGRATKGGPIKAFGDCMQMRTGKRKAGEAIGFIPVLGSLALAM
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
GYTVVVGWIFKYTYLAFSGKLSAMGNDMSAIGGMFGSTASTFGNNMWLIIAMVVTAVIMA
HHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
LGIAGGIEKANKVMMPLLFIMFVGLGIYIFTLPGSSAGYKYIFTLNPKELLDIKLWIYAF
HHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHH
GQAFFSLSIAGNGTVIYGSYLSDKENIVSSARNVAVFDTIAALLAAFVIIPGMAAGGAEL
HHHHEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
SSGGPGLMFIYLVNVFNGMPGGKIVGIVFYVCVLFAGMSSLVNLYEAPVATIQEKLKLNR
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASVGIIAVAGCVVSLVIQGIVSGWMDAVSIYICPLGAMLAAIMFFWVEGKKFAVDAVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GADKPIGKWFVPLGKYVLVPLALVALIAGALLGGIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKKGTKAMGNNGIELERDGFKSRTGFILACIGSAVGMGNIWRFPYMVSAWGGMTFLIPY
CCCCCCCCCCCCCCEECCCCCCCCCCEEEEEHHHHCCCCCCCCCCHHHHHHCCHHHHHHH
VLFVILIGSTGVIEEMALGRATKGGPIKAFGDCMQMRTGKRKAGEAIGFIPVLGSLALAM
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHH
GYTVVVGWIFKYTYLAFSGKLSAMGNDMSAIGGMFGSTASTFGNNMWLIIAMVVTAVIMA
HHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
LGIAGGIEKANKVMMPLLFIMFVGLGIYIFTLPGSSAGYKYIFTLNPKELLDIKLWIYAF
HHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHH
GQAFFSLSIAGNGTVIYGSYLSDKENIVSSARNVAVFDTIAALLAAFVIIPGMAAGGAEL
HHHHEEEEEECCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
SSGGPGLMFIYLVNVFNGMPGGKIVGIVFYVCVLFAGMSSLVNLYEAPVATIQEKLKLNR
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASVGIIAVAGCVVSLVIQGIVSGWMDAVSIYICPLGAMLAAIMFFWVEGKKFAVDAVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GADKPIGKWFVPLGKYVLVPLALVALIAGALLGGIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]