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The map label for this gene is plsC [H]

Identifier: 238916132

GI number: 238916132

Start: 192996

End: 193733

Strand: Reverse

Name: plsC [H]

Synonym: EUBELI_00166

Alternate gene names: 238916132

Gene position: 193733-192996 (Counterclockwise)

Preceding gene: 238916133

Following gene: 238916123

Centisome position: 9.04

GC content: 38.21

Gene sequence:

>738_bases
ATGATAAGACTCATATTAATCGTTATATTTGCAATAATAATATTCTTTGCCAGCCTTATAATGCTTCCTATATTCTGGCT
TATTGGCAAGTTCAATCAGGATGCTAAGGATCGCGGAAGTCTCCGCTTTGTACAGGGTGTTTTTAAGGTTGTTCTTTTTC
TGTCTGGTGTTACAACAACCGTAAAAGGACTTGAAAATCTCCCTAAAGACAAAGAAGCTGTACTTTTTGTAGGCAATCAT
CATGGTTTCTTTGACACAATTATTTCTTACACATACATGAAGCCCAGAACTGGCTTTGTTGCCAAGAAAGAGATTGAAAA
AGTCCCTCTTCTTAATATATGGATGAGATATCTTTACTGTCTCTTCCTTGACAGAAAAAATATGAAAGAAGGTTTAAAGA
CTATCCTTACCGGCATTGATTACTTGAAAGCTGGAACTTCAATTGTTATATTCCCTGAAGGAACAAGAAATAAAAGCATT
GATGGTGTTCTCCCTTTCCATGCAGGAAGCTTTAAGCTTGCTGAAAAATCAGGCTGCAAGATTATTCCTATGGTACAGAA
CAACACAGCTGCTGCATTAGAAGACCACCTTCCATTCTTTAAAAAGACTCACACTGTCCTTGAATTCGGCAAACCAATCG
ATGTCGCCAGCATGGATCGCGAGCAGAAAAAGACTCTTGCTAAAGATGTGCAGGATCTTATTGAGAAGATGTACGAGGAA
AATAAGGCGCTTGTGTAG

Upstream 100 bases:

>100_bases
AATTCACTATTCCAGTGGAGCAAAGGCCTATGTAAAGAGCTGAGATATCTCGCGGTACCAGGCTTAACTTAATATCAAAA
AATGAAATGGAGAACATACA

Downstream 100 bases:

>100_bases
GTTTGTGTGAGAGGGGACGGTCATGAGGCGAAAGTATATGCCAGCTTCGGACGCGCTCCCGCTCGGACGAATGCGTAGCG
TGTACTAAGCGCACTTTCTC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIRLILIVIFAIIIFFASLIMLPIFWLIGKFNQDAKDRGSLRFVQGVFKVVLFLSGVTTTVKGLENLPKDKEAVLFVGNH
HGFFDTIISYTYMKPRTGFVAKKEIEKVPLLNIWMRYLYCLFLDRKNMKEGLKTILTGIDYLKAGTSIVIFPEGTRNKSI
DGVLPFHAGSFKLAEKSGCKIIPMVQNNTAAALEDHLPFFKKTHTVLEFGKPIDVASMDREQKKTLAKDVQDLIEKMYEE
NKALV

Sequences:

>Translated_245_residues
MIRLILIVIFAIIIFFASLIMLPIFWLIGKFNQDAKDRGSLRFVQGVFKVVLFLSGVTTTVKGLENLPKDKEAVLFVGNH
HGFFDTIISYTYMKPRTGFVAKKEIEKVPLLNIWMRYLYCLFLDRKNMKEGLKTILTGIDYLKAGTSIVIFPEGTRNKSI
DGVLPFHAGSFKLAEKSGCKIIPMVQNNTAAALEDHLPFFKKTHTVLEFGKPIDVASMDREQKKTLAKDVQDLIEKMYEE
NKALV
>Mature_245_residues
MIRLILIVIFAIIIFFASLIMLPIFWLIGKFNQDAKDRGSLRFVQGVFKVVLFLSGVTTTVKGLENLPKDKEAVLFVGNH
HGFFDTIISYTYMKPRTGFVAKKEIEKVPLLNIWMRYLYCLFLDRKNMKEGLKTILTGIDYLKAGTSIVIFPEGTRNKSI
DGVLPFHAGSFKLAEKSGCKIIPMVQNNTAAALEDHLPFFKKTHTVLEFGKPIDVASMDREQKKTLAKDVQDLIEKMYEE
NKALV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789395, Length=177, Percent_Identity=28.2485875706215, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=233, Percent_Identity=27.8969957081545, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364648, Length=217, Percent_Identity=27.1889400921659, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582856, Length=217, Percent_Identity=27.1889400921659, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582854, Length=217, Percent_Identity=27.1889400921659, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27840; Mature: 27840

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLILIVIFAIIIFFASLIMLPIFWLIGKFNQDAKDRGSLRFVQGVFKVVLFLSGVTTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHH
VKGLENLPKDKEAVLFVGNHHGFFDTIISYTYMKPRTGFVAKKEIEKVPLLNIWMRYLYC
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
LFLDRKNMKEGLKTILTGIDYLKAGTSIVIFPEGTRNKSIDGVLPFHAGSFKLAEKSGCK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEECCCCCCEEEHHCCCCE
IIPMVQNNTAAALEDHLPFFKKTHTVLEFGKPIDVASMDREQKKTLAKDVQDLIEKMYEE
EEEEECCCCHHHHHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHC
NKALV
CCCCC
>Mature Secondary Structure
MIRLILIVIFAIIIFFASLIMLPIFWLIGKFNQDAKDRGSLRFVQGVFKVVLFLSGVTTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHH
VKGLENLPKDKEAVLFVGNHHGFFDTIISYTYMKPRTGFVAKKEIEKVPLLNIWMRYLYC
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHH
LFLDRKNMKEGLKTILTGIDYLKAGTSIVIFPEGTRNKSIDGVLPFHAGSFKLAEKSGCK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEECCCCCCEEEHHCCCCE
IIPMVQNNTAAALEDHLPFFKKTHTVLEFGKPIDVASMDREQKKTLAKDVQDLIEKMYEE
EEEEECCCCHHHHHHHCCHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHC
NKALV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]