Click here to switch to the map view.

The map label for this gene is murG

Identifier: 238916019

GI number: 238916019

Start: 57433

End: 58497

Strand: Reverse

Name: murG

Synonym: EUBELI_00052

Alternate gene names: 238916019

Gene position: 58497-57433 (Counterclockwise)

Preceding gene: 238916020

Following gene: 238916018

Centisome position: 2.73

GC content: 41.97

Gene sequence:

>1065_bases
ATGAAAAAAATAGTACTTACCGGTGGTGGTACTGCCGGACATGTAACACCTAATATTGCCCTGCTTCCAAGCCTTAAGGA
AGCCGGCTACGAGGTTTTCTATATCGGTTCATATACCGGTATTGAAAAAACTCTTATTGAAGATCTTGGAATTCCTTATT
ATGGTATTTCATCCGGCAAATTAAGAAGATACAGAAGTCTTAAGAATCTGTCTGATCCATTCCGTGTGCTTCATGGACTT
TTTCAGGCTAAGAGACTTATGAAAAAAATCAAACCTGATATCGTATTTTCTAAGGGAGGCTTCGTGTCTGTACCTGTTGT
TCTTGCCGCCGGAAGCCGTCATATTCCAGTAATTATCCACGAATCTGATATGACACCCGGCCTTGCCAACAAGATTGCTA
TGAGAAAAGCAACTAAAATATGCTGCAATTTCCCAGAGACACTCAAGTACCTTCCTGAAGGAAAAGCTGTTCTTACAGGT
TCTCCTATCAGACAGGAGCTTTTGCTTGGCAACAAAGCTGCCGGACTTGACCTTTGCAACTTCACAACTGACAAACCTAT
TATTCTTGTTGTCGGCGGAAGTACTGGCGCTGTCCATGTAAATGATGCTGTAAGAAGCATTTTACCTGAACTTCTTAAGG
ATTTTCAGGTTGTTCACCTGTGTGGAAAAGGAAAGATGGACGATTCTCTCAATGGAACTCCCGGCTATGTCCAGTTCGAG
TACATAAGCGAGCAGATGCGCGACCTTTTCGCAATCAGTTCTATTGTTATCTCGCGTGCGGGTGCCAATGCCATATGCGA
ACTGCTTGCTCTCAAGAAGCCTAATCTTCTGATTCCGCTTTCTGCTAATGCAAGCCGTGGCGACCAGATTCTTAATGCCA
ATTCTTTCAAGGAGCATGGTTATTCCATGGTTCTTACGGAGGAGGATATGAATAAGGATACCTTACTTGCCGCAGTCCGC
AAGCTTTATGCTGACAGACACCAGTACATCATTAATATGGAAAAAAGTGAGCAGCAGGATTCTATTGACAAAATTATGAA
TTTAATTAAAGATAATAGTAAATAA

Upstream 100 bases:

>100_bases
CTCTGCATGCATTGCAGCTTTAAGGAAAGATTTGCTCATAAAATGTAATGATACATTTGAACAAATCGGACATTTTATTA
TATTTTCAGGAGAATGACCT

Downstream 100 bases:

>100_bases
TAATCCGGAGGTGATTTTATGGGCGCTGTTAAACATAGCCGTCAGCGTGACGCTATCAAAACATTTCTTATGTCACGCAA
AGACCACCCAACTGCCGATG

Product: hypothetical protein

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKKIVLTGGGTAGHVTPNIALLPSLKEAGYEVFYIGSYTGIEKTLIEDLGIPYYGISSGKLRRYRSLKNLSDPFRVLHGL
FQAKRLMKKIKPDIVFSKGGFVSVPVVLAAGSRHIPVIIHESDMTPGLANKIAMRKATKICCNFPETLKYLPEGKAVLTG
SPIRQELLLGNKAAGLDLCNFTTDKPIILVVGGSTGAVHVNDAVRSILPELLKDFQVVHLCGKGKMDDSLNGTPGYVQFE
YISEQMRDLFAISSIVISRAGANAICELLALKKPNLLIPLSANASRGDQILNANSFKEHGYSMVLTEEDMNKDTLLAAVR
KLYADRHQYIINMEKSEQQDSIDKIMNLIKDNSK

Sequences:

>Translated_354_residues
MKKIVLTGGGTAGHVTPNIALLPSLKEAGYEVFYIGSYTGIEKTLIEDLGIPYYGISSGKLRRYRSLKNLSDPFRVLHGL
FQAKRLMKKIKPDIVFSKGGFVSVPVVLAAGSRHIPVIIHESDMTPGLANKIAMRKATKICCNFPETLKYLPEGKAVLTG
SPIRQELLLGNKAAGLDLCNFTTDKPIILVVGGSTGAVHVNDAVRSILPELLKDFQVVHLCGKGKMDDSLNGTPGYVQFE
YISEQMRDLFAISSIVISRAGANAICELLALKKPNLLIPLSANASRGDQILNANSFKEHGYSMVLTEEDMNKDTLLAAVR
KLYADRHQYIINMEKSEQQDSIDKIMNLIKDNSK
>Mature_354_residues
MKKIVLTGGGTAGHVTPNIALLPSLKEAGYEVFYIGSYTGIEKTLIEDLGIPYYGISSGKLRRYRSLKNLSDPFRVLHGL
FQAKRLMKKIKPDIVFSKGGFVSVPVVLAAGSRHIPVIIHESDMTPGLANKIAMRKATKICCNFPETLKYLPEGKAVLTG
SPIRQELLLGNKAAGLDLCNFTTDKPIILVVGGSTGAVHVNDAVRSILPELLKDFQVVHLCGKGKMDDSLNGTPGYVQFE
YISEQMRDLFAISSIVISRAGANAICELLALKKPNLLIPLSANASRGDQILNANSFKEHGYSMVLTEEDMNKDTLLAAVR
KLYADRHQYIINMEKSEQQDSIDKIMNLIKDNSK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=356, Percent_Identity=28.6516853932584, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_EUBE2 (C4Z1B5)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002929536.1
- ProteinModelPortal:   C4Z1B5
- GeneID:   7956787
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_00052
- OMA:   HICGKGN
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38806; Mature: 38806

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVLTGGGTAGHVTPNIALLPSLKEAGYEVFYIGSYTGIEKTLIEDLGIPYYGISSGK
CCEEEEECCCCCCCCCCCEEECCCHHHCCEEEEEEECCCCHHHHHHHHCCCCEEECCCCH
LRRYRSLKNLSDPFRVLHGLFQAKRLMKKIKPDIVFSKGGFVSVPVVLAAGSRHIPVIIH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCEEEEE
ESDMTPGLANKIAMRKATKICCNFPETLKYLPEGKAVLTGSPIRQELLLGNKAAGLDLCN
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCEEEC
FTTDKPIILVVGGSTGAVHVNDAVRSILPELLKDFQVVHLCGKGKMDDSLNGTPGYVQFE
CCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEHH
YISEQMRDLFAISSIVISRAGANAICELLALKKPNLLIPLSANASRGDQILNANSFKEHG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCHHHCC
YSMVLTEEDMNKDTLLAAVRKLYADRHQYIINMEKSEQQDSIDKIMNLIKDNSK
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIVLTGGGTAGHVTPNIALLPSLKEAGYEVFYIGSYTGIEKTLIEDLGIPYYGISSGK
CCEEEEECCCCCCCCCCCEEECCCHHHCCEEEEEEECCCCHHHHHHHHCCCCEEECCCCH
LRRYRSLKNLSDPFRVLHGLFQAKRLMKKIKPDIVFSKGGFVSVPVVLAAGSRHIPVIIH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCEEEEE
ESDMTPGLANKIAMRKATKICCNFPETLKYLPEGKAVLTGSPIRQELLLGNKAAGLDLCN
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCEEEC
FTTDKPIILVVGGSTGAVHVNDAVRSILPELLKDFQVVHLCGKGKMDDSLNGTPGYVQFE
CCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEHH
YISEQMRDLFAISSIVISRAGANAICELLALKKPNLLIPLSANASRGDQILNANSFKEHG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCHHHCC
YSMVLTEEDMNKDTLLAAVRKLYADRHQYIINMEKSEQQDSIDKIMNLIKDNSK
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA