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The map label for this gene is dsdA [H]

Identifier: 238897188

GI number: 238897188

Start: 5187289

End: 5188617

Strand: Direct

Name: dsdA [H]

Synonym: KP1_5458

Alternate gene names: 238897188

Gene position: 5187289-5188617 (Clockwise)

Preceding gene: 238897187

Following gene: 238897194

Centisome position: 98.83

GC content: 61.1

Gene sequence:

>1329_bases
ATGAAAAACGCTGACCTGACCACCTTAACCGCGACCTTCCCGCTTGTGCAGGATCTGATCGCCCTGAAAGAAACTACCTG
GTTTAACCCGGCAACCACCACCCTGGCGGAGGGGTTGCCTTACGTCGGTCTGACCGCCGACGATGTGCAAGACGCCCATG
CCCGCCTTCAGCGCTTCGCGCCCTATCTGGCGGCAGCCTTCCCGGAAACCGCCGCGAGCGGCGGGATTATCGAATCAGAA
GTGGTTGCCATTCCGGCAATGAAACGCAGCCTTGAGCAAAAATTCGGCCAGCCAATTAGCGGCGAACTGCTGCTGAAAAA
AGACAGCCATCTGCCAATCTCCGGCTCAATCAAAGCGCGCGGTGGGATTTATGAAGTGCTGACCCATGCGGAAAAGCTGG
CGCTGGAAGCCGGGCTGCTGACGACCGCAGACGATTATCGCAAATTGCTGACGCCGGAGTTTAAACAGTTCTTTAGCCAG
TTCAGCATCGCCGTCGGCTCCACCGGCAACCTTGGGATGTCGATCGGCATCATGAGCGCGCGCATTGGTTTTCAAGTCAC
GGTGCATATGTCCGCCGATGCCAGGGCGTGGAAAAAAGCCAAACTGCGCAGCCACGGCGTAACGGTGGTTGAGTATGAAG
AGGACTATGGCGTGGCGGTCGAACAGGGGCGCAAGGCAGCGGAATCCGATCCGAACTGCTTTTTCATTGATGATGAAAAC
TCACGCACGCTGTTCCTCGGCTATGCCGTAGCCGGCGAGCGCCTGAAGGCGCAGTTTGCCAAAGCAGGGCGCGTGGTCGA
TGCCGATCACCCGCTGTTCGTCTATCTGCCGTGCGGCGTCGGCGGCGGCCCCGGCGGCGTGGCATTTGGCCTGAAGCTGG
CCTTCGGCGACCACGTTCACTGCCTGTTCGCCGAACCGACCCATTCGCCATGCATGCTGCTCGGCGTCTATACCGGGCTC
CACGACCAGATAGCGGTGCAGGATTTAGGTATTGATAACCTGACCGCGGCCGACGGTCTGGCGGTCGGCAGGGCGTCCGG
GTTCGTTGGCCGGGCAATGGAGCGCCTGCTCGACGGGTTCTATACCCTTGACGACCAGACGATGTATGACATGCTGGGCT
GGCTGGCGGCAGCGGAAAATATCCGCCTTGAACCCTCCGCGCTGGCCGGGATGGCCGGAGCGCAGCGGGTCTGCGCCAGC
AAAGCGTACCATCAGCTGCAGGGGCTGAGTGAGCAACAGCTGCAGCAGGCCACCCACCTGGTGTGGGCCACCGGCGGCGG
CATGGTGCCGGAAGAGGAAATGGCGCAGTACCTGGCGAAGGGGCGCTAA

Upstream 100 bases:

>100_bases
ACGTTCAAGTACTACACGACAGCGACATTTATCGCGTCGCTACTTGCACTGGCCGCCACCTTCCTGCTTTCTTTCATCAT
CTAAGCGAACGAGACGTAAT

Downstream 100 bases:

>100_bases
TCTTTAGCGCAGCAGCGGCATCAGCGCCTCTGGTGGCCGCTGCTGTCGTCGCAGGTCCCGCATCACTCGCATATAGGGCC
CGCTAAAATCGTAGAACTGC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKNADLTTLTATFPLVQDLIALKETTWFNPATTTLAEGLPYVGLTADDVQDAHARLQRFAPYLAAAFPETAASGGIIESE
VVAIPAMKRSLEQKFGQPISGELLLKKDSHLPISGSIKARGGIYEVLTHAEKLALEAGLLTTADDYRKLLTPEFKQFFSQ
FSIAVGSTGNLGMSIGIMSARIGFQVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAESDPNCFFIDDEN
SRTLFLGYAVAGERLKAQFAKAGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCLFAEPTHSPCMLLGVYTGL
HDQIAVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLDDQTMYDMLGWLAAAENIRLEPSALAGMAGAQRVCAS
KAYHQLQGLSEQQLQQATHLVWATGGGMVPEEEMAQYLAKGR

Sequences:

>Translated_442_residues
MKNADLTTLTATFPLVQDLIALKETTWFNPATTTLAEGLPYVGLTADDVQDAHARLQRFAPYLAAAFPETAASGGIIESE
VVAIPAMKRSLEQKFGQPISGELLLKKDSHLPISGSIKARGGIYEVLTHAEKLALEAGLLTTADDYRKLLTPEFKQFFSQ
FSIAVGSTGNLGMSIGIMSARIGFQVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAESDPNCFFIDDEN
SRTLFLGYAVAGERLKAQFAKAGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCLFAEPTHSPCMLLGVYTGL
HDQIAVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLDDQTMYDMLGWLAAAENIRLEPSALAGMAGAQRVCAS
KAYHQLQGLSEQQLQQATHLVWATGGGMVPEEEMAQYLAKGR
>Mature_442_residues
MKNADLTTLTATFPLVQDLIALKETTWFNPATTTLAEGLPYVGLTADDVQDAHARLQRFAPYLAAAFPETAASGGIIESE
VVAIPAMKRSLEQKFGQPISGELLLKKDSHLPISGSIKARGGIYEVLTHAEKLALEAGLLTTADDYRKLLTPEFKQFFSQ
FSIAVGSTGNLGMSIGIMSARIGFQVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAESDPNCFFIDDEN
SRTLFLGYAVAGERLKAQFAKAGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCLFAEPTHSPCMLLGVYTGL
HDQIAVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLDDQTMYDMLGWLAAAENIRLEPSALAGMAGAQRVCAS
KAYHQLQGLSEQQLQQATHLVWATGGGMVPEEEMAQYLAKGR

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=442, Percent_Identity=85.5203619909502, Blast_Score=777, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47462; Mature: 47462

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNADLTTLTATFPLVQDLIALKETTWFNPATTTLAEGLPYVGLTADDVQDAHARLQRFA
CCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
PYLAAAFPETAASGGIIESEVVAIPAMKRSLEQKFGQPISGELLLKKDSHLPISGSIKAR
HHHHHHCCCHHCCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
GGIYEVLTHAEKLALEAGLLTTADDYRKLLTPEFKQFFSQFSIAVGSTGNLGMSIGIMSA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEEEEEE
RIGFQVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAESDPNCFFIDDEN
EEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHCCCCCCEEEEECCC
SRTLFLGYAVAGERLKAQFAKAGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCEE
CLFAEPTHSPCMLLGVYTGLHDQIAVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEEHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YTLDDQTMYDMLGWLAAAENIRLEPSALAGMAGAQRVCASKAYHQLQGLSEQQLQQATHL
EECCCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEE
VWATGGGMVPEEEMAQYLAKGR
EEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKNADLTTLTATFPLVQDLIALKETTWFNPATTTLAEGLPYVGLTADDVQDAHARLQRFA
CCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
PYLAAAFPETAASGGIIESEVVAIPAMKRSLEQKFGQPISGELLLKKDSHLPISGSIKAR
HHHHHHCCCHHCCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
GGIYEVLTHAEKLALEAGLLTTADDYRKLLTPEFKQFFSQFSIAVGSTGNLGMSIGIMSA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEEEEEE
RIGFQVTVHMSADARAWKKAKLRSHGVTVVEYEEDYGVAVEQGRKAAESDPNCFFIDDEN
EEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHCCCCCCEEEEECCC
SRTLFLGYAVAGERLKAQFAKAGRVVDADHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCEE
CLFAEPTHSPCMLLGVYTGLHDQIAVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEEHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YTLDDQTMYDMLGWLAAAENIRLEPSALAGMAGAQRVCASKAYHQLQGLSEQQLQQATHL
EECCCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEE
VWATGGGMVPEEEMAQYLAKGR
EEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA