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The map label for this gene is phnW [H]

Identifier: 238897169

GI number: 238897169

Start: 5169067

End: 5170170

Strand: Direct

Name: phnW [H]

Synonym: KP1_5436

Alternate gene names: 238897169

Gene position: 5169067-5170170 (Clockwise)

Preceding gene: 238897163

Following gene: 238897170

Centisome position: 98.49

GC content: 59.33

Gene sequence:

>1104_bases
ATGACTTCACGAAATTACCTGCTGCTGACCCCCGGCCCGTTAACCACCTCCCGTACGGTGAAAGAGGCGATGTTGTTCGA
TAGCTGCACCTGGGATGATGATTACAATCTCGGCGTGGTACAGACCATTCGCCAGCAGCTGGTGCAGTTGGCTACCCCGG
CCGACGGTTATACCGCAGTGCTGCTGCAGGGTAGCGGCAGCTACGCGGTCGAAGCGGTGCTCGGCAGCGTCATCGGCGAA
CAGGGCAAAGTGCTAATCGTCAGCAATGGCGCCTATGGCGCGCGTATGATTGAGATGGCGCAACTGATGGGCATCGCCTG
CCACCCTTACGACTGTGGCGAAGTCTCCCGTCCGGACGCGGCCGCGATCGAACAGATCCTGCAGAACGACCCGGCGATCA
CCCATATCGCGATGGTACACAGCGAAACCACCACCGGTATGCTGAATCCGATCGAAGAGGTGGCCGAACTGGCGAAACGG
TACAATAAACGCTATATCGTCGATGCGATGAGCAGCTTCGGCGGCATTCCACTGGATATCGCCGCGCTGAATATTGATTA
CCTGATAAGCTCCGCCAATAAATGCATTCAGGGCGTGCCGGGCTTTGCCTTCGTGATTGCCCGTGAAGCGGAGCTGGCCG
CCTGCAAAGGCCGTTCACGCTCGCTGTCGCTGGATCTGTACGCCCAGTGGCGCTGCATGGAGGACAACCACGGCAAGTGG
CGCTTCACCTCGCCGACACATACCGTGCTGGCCTTCGCCCAGGCGCTGAAAGAGCTGGCGCAGGAGGGCGGCGTCAGCGC
TCGCCATCAGCGCTACCGCAACAATCAGCGCCGGCTGGTCGCCGGGATGCGCGCGCTCGGCTTCCGGCCGCTGCTCGACG
ATAGCCTGCACTCGCCGATCATTACCGCCTTTTATTCACCGGATGCGCCGCAGTATCGCTTTCACACCTTCTACCAGAAG
CTGAAAGATCAGGGCTTCGTTATCTATCCGGGCAAAGTATCGCAAAGCGACTGCTTCCGCATCGGCAACATTGGCGAAGT
CTACGACGCCGATATCACCGCCCTGCTGGCGGCTATCAACAACGCCATGTACTGGAAACAATAA

Upstream 100 bases:

>100_bases
CAGATGAATTTTTTGTTGCAGCGCCACATTTCCTTTGACCCTTTCCCGGCTTTGTCTCCATGATAACTATAAATCTGGTA
TAGACCAAATGGTGAGACAA

Downstream 100 bases:

>100_bases
GGAACCGCCATGAACCGTATTAGCGCACTGATCCTTGACTGGGCAGGCACCACCGTAGACTTCGGCTCTTTCGCCCCGAC
GCAAATCTTCGTCGAGGCCT

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNLGVVQTIRQQLVQLATPADGYTAVLLQGSGSYAVEAVLGSVIGE
QGKVLIVSNGAYGARMIEMAQLMGIACHPYDCGEVSRPDAAAIEQILQNDPAITHIAMVHSETTTGMLNPIEEVAELAKR
YNKRYIVDAMSSFGGIPLDIAALNIDYLISSANKCIQGVPGFAFVIAREAELAACKGRSRSLSLDLYAQWRCMEDNHGKW
RFTSPTHTVLAFAQALKELAQEGGVSARHQRYRNNQRRLVAGMRALGFRPLLDDSLHSPIITAFYSPDAPQYRFHTFYQK
LKDQGFVIYPGKVSQSDCFRIGNIGEVYDADITALLAAINNAMYWKQ

Sequences:

>Translated_367_residues
MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNLGVVQTIRQQLVQLATPADGYTAVLLQGSGSYAVEAVLGSVIGE
QGKVLIVSNGAYGARMIEMAQLMGIACHPYDCGEVSRPDAAAIEQILQNDPAITHIAMVHSETTTGMLNPIEEVAELAKR
YNKRYIVDAMSSFGGIPLDIAALNIDYLISSANKCIQGVPGFAFVIAREAELAACKGRSRSLSLDLYAQWRCMEDNHGKW
RFTSPTHTVLAFAQALKELAQEGGVSARHQRYRNNQRRLVAGMRALGFRPLLDDSLHSPIITAFYSPDAPQYRFHTFYQK
LKDQGFVIYPGKVSQSDCFRIGNIGEVYDADITALLAAINNAMYWKQ
>Mature_366_residues
TSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNLGVVQTIRQQLVQLATPADGYTAVLLQGSGSYAVEAVLGSVIGEQ
GKVLIVSNGAYGARMIEMAQLMGIACHPYDCGEVSRPDAAAIEQILQNDPAITHIAMVHSETTTGMLNPIEEVAELAKRY
NKRYIVDAMSSFGGIPLDIAALNIDYLISSANKCIQGVPGFAFVIAREAELAACKGRSRSLSLDLYAQWRCMEDNHGKWR
FTSPTHTVLAFAQALKELAQEGGVSARHQRYRNNQRRLVAGMRALGFRPLLDDSLHSPIITAFYSPDAPQYRFHTFYQKL
KDQGFVIYPGKVSQSDCFRIGNIGEVYDADITALLAAINNAMYWKQ

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=320, Percent_Identity=25.625, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536281, Length=352, Percent_Identity=21.875, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 40491; Mature: 40360

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNLGVVQTIRQQLVQLATPADGYTAV
CCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
LLQGSGSYAVEAVLGSVIGEQGKVLIVSNGAYGARMIEMAQLMGIACHPYDCGEVSRPDA
EEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AAIEQILQNDPAITHIAMVHSETTTGMLNPIEEVAELAKRYNKRYIVDAMSSFGGIPLDI
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHCCCCCEEE
AALNIDYLISSANKCIQGVPGFAFVIAREAELAACKGRSRSLSLDLYAQWRCMEDNHGKW
EEEHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEEEEEEEECCCCCE
RFTSPTHTVLAFAQALKELAQEGGVSARHQRYRNNQRRLVAGMRALGFRPLLDDSLHSPI
EECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCE
ITAFYSPDAPQYRFHTFYQKLKDQGFVIYPGKVSQSDCFRIGNIGEVYDADITALLAAIN
EEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHH
NAMYWKQ
CCCCCCC
>Mature Secondary Structure 
TSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNLGVVQTIRQQLVQLATPADGYTAV
CCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
LLQGSGSYAVEAVLGSVIGEQGKVLIVSNGAYGARMIEMAQLMGIACHPYDCGEVSRPDA
EEECCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AAIEQILQNDPAITHIAMVHSETTTGMLNPIEEVAELAKRYNKRYIVDAMSSFGGIPLDI
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHCCCCCEEE
AALNIDYLISSANKCIQGVPGFAFVIAREAELAACKGRSRSLSLDLYAQWRCMEDNHGKW
EEEHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEEEEEEEECCCCCE
RFTSPTHTVLAFAQALKELAQEGGVSARHQRYRNNQRRLVAGMRALGFRPLLDDSLHSPI
EECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCE
ITAFYSPDAPQYRFHTFYQKLKDQGFVIYPGKVSQSDCFRIGNIGEVYDADITALLAAIN
EEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHH
NAMYWKQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA