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The map label for this gene is glvC [H]

Identifier: 238897117

GI number: 238897117

Start: 5113894

End: 5115453

Strand: Direct

Name: glvC [H]

Synonym: KP1_5375

Alternate gene names: 238897117

Gene position: 5113894-5115453 (Clockwise)

Preceding gene: 238897116

Following gene: 238897118

Centisome position: 97.43

GC content: 54.17

Gene sequence:

>1560_bases
ATGCCTGAAATACGTCAGCGTATTCTGGAGAATATGCAAAAATTCTCCCGGGCCATGATCGGCGCCGTATTGTTCTTGCC
GGTCATTGGCTTAATTCTGGCCCTCAGTTCAGTATTAACTAATCCGACATTAATTGCTGAAACCAGTTTCTTACATCAGC
TTGGGCAAATGCTCGGCGACACCTTTTGGCCTTTATTTGGCAACCTCGGCTTATTATTTTGCGTCGGCATCAGCTATGGC
CTGGCAAAGGATAAAAAAACCGAAGTCGCACTGGTTTCAGTGATGTGCTTTATTATGTTTCTTGGCGCCAACCACTCCTG
GCTGGAACACACCCATGGACTCGCCGAAAAAATTAACGGTGAATATTATGGCACCGGGCAAACCCAGCTGCTGGGCTTTG
TGGTGGTGGATATGGGCGTTTTCCTGGGCATTATTCTCGGCTGCACGATTGCGTGGGTGCACAATAAAGTCTCTGCCATT
GAGCTGCCTGGCGCGCTGTCGATGTACGGCGGCGCCAAGCTGACGCTGGTGGCGATGACGCCGGTGGTTATCTTCTACGC
CATCGCCTTTACCTGGATTTGGCCCTTTATGACCCACGGCATCTCCGCCCTCATCGGTTTTATGAAAAATGCCGGGGTCG
CCGGGGTCTTCGTCTATGGTTTCTTTGAAAAATTCCTTATCCCCACCGGCCTGCACCATTTCGTCTGGTCCCCCTTCCAG
CTCACCCAGATTGGCGGCACGCTGAACGTGGATGGTCAGGTGGTCTCCGGCACCCAGGCCATTTTCCTCGCCTATATGCG
CCATCCCGACCTGACGCCGGTCATGAACGACGCATTACGTTTTTCGCAGCAAGGGATGACCACTATCTTTGGCCTGGCGG
GCGCCTCGCTGGCGTTCTACCACACCGCGAAACCGGAGAAGAAAGCGATGGCGAAGGCGATTCTGCTGCCGGCGATTATC
ACCTCGATGCTGACCGGCATCACCGAGCCGATTGAGTTCACCTTCTTATTTGTCTCACCGCTGCTGTGGGTGATCCACGC
GACGTTAACCGCCGCCTCGCAGGCCATTTGCGACATCTTCACCGTACGTCCCTGGGGAGCATCGGGCCTGATCGAGTTTC
TGATCTATAACCTGCCGCTGCCGGTCTCCTTAACGCGCTGGCCGGGCTATGTCCTTATCGGTATCGGCCAGTTCGCCGTC
TACTACGTGATTTTCCGCACCCTGGTGGTGAAGCTGAACCTGAAAACGCCGGGCCGGGAAGATGACGAGAACGTGAAGCT
CTACAGCAAAGCAGAGTACCGCCAGAAAGTCGCGCAACCGCAGTCGGTCACCGATGACATTATCCGCGGCCTCGGGGGCA
AGGAGAATATTCTCTCCGTCGATAATTGTTTTACTCGCCTGCGCGTGGCCGTGCGCGATATGGCGCGGGTTGATGACACG
CAATTAAAAAATACCGGCGCCAACGGCGTCGTACGCAATCGAAATGAAGTTCAGGTTATTTATGGCGTCAAAGTGGGACA
GGTACGTTCCCGGGTTGATAACTGGTTAGCAGAAAATTAA

Upstream 100 bases:

>100_bases
GCAACAGGTTCCTTTCAAATATCAGAGTTGCTATAACCAAATCACTGGAAGTCGATAAAAAACCGCTCCCTGTACCTACA
AAAATATAAAAGGATCAATC

Downstream 100 bases:

>100_bases
TGAGGAGTATTTATGAAATTAACCGTATTAGGCGGGGGCGGCGTTCGCTCTGCATTTTTAGCGAAATCTCTGGCCTATAA
CGCTCACCGCATTGGTTTAA

Product: PTS system phosphotransferase

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MPEIRQRILENMQKFSRAMIGAVLFLPVIGLILALSSVLTNPTLIAETSFLHQLGQMLGDTFWPLFGNLGLLFCVGISYG
LAKDKKTEVALVSVMCFIMFLGANHSWLEHTHGLAEKINGEYYGTGQTQLLGFVVVDMGVFLGIILGCTIAWVHNKVSAI
ELPGALSMYGGAKLTLVAMTPVVIFYAIAFTWIWPFMTHGISALIGFMKNAGVAGVFVYGFFEKFLIPTGLHHFVWSPFQ
LTQIGGTLNVDGQVVSGTQAIFLAYMRHPDLTPVMNDALRFSQQGMTTIFGLAGASLAFYHTAKPEKKAMAKAILLPAII
TSMLTGITEPIEFTFLFVSPLLWVIHATLTAASQAICDIFTVRPWGASGLIEFLIYNLPLPVSLTRWPGYVLIGIGQFAV
YYVIFRTLVVKLNLKTPGREDDENVKLYSKAEYRQKVAQPQSVTDDIIRGLGGKENILSVDNCFTRLRVAVRDMARVDDT
QLKNTGANGVVRNRNEVQVIYGVKVGQVRSRVDNWLAEN

Sequences:

>Translated_519_residues
MPEIRQRILENMQKFSRAMIGAVLFLPVIGLILALSSVLTNPTLIAETSFLHQLGQMLGDTFWPLFGNLGLLFCVGISYG
LAKDKKTEVALVSVMCFIMFLGANHSWLEHTHGLAEKINGEYYGTGQTQLLGFVVVDMGVFLGIILGCTIAWVHNKVSAI
ELPGALSMYGGAKLTLVAMTPVVIFYAIAFTWIWPFMTHGISALIGFMKNAGVAGVFVYGFFEKFLIPTGLHHFVWSPFQ
LTQIGGTLNVDGQVVSGTQAIFLAYMRHPDLTPVMNDALRFSQQGMTTIFGLAGASLAFYHTAKPEKKAMAKAILLPAII
TSMLTGITEPIEFTFLFVSPLLWVIHATLTAASQAICDIFTVRPWGASGLIEFLIYNLPLPVSLTRWPGYVLIGIGQFAV
YYVIFRTLVVKLNLKTPGREDDENVKLYSKAEYRQKVAQPQSVTDDIIRGLGGKENILSVDNCFTRLRVAVRDMARVDDT
QLKNTGANGVVRNRNEVQVIYGVKVGQVRSRVDNWLAEN
>Mature_518_residues
PEIRQRILENMQKFSRAMIGAVLFLPVIGLILALSSVLTNPTLIAETSFLHQLGQMLGDTFWPLFGNLGLLFCVGISYGL
AKDKKTEVALVSVMCFIMFLGANHSWLEHTHGLAEKINGEYYGTGQTQLLGFVVVDMGVFLGIILGCTIAWVHNKVSAIE
LPGALSMYGGAKLTLVAMTPVVIFYAIAFTWIWPFMTHGISALIGFMKNAGVAGVFVYGFFEKFLIPTGLHHFVWSPFQL
TQIGGTLNVDGQVVSGTQAIFLAYMRHPDLTPVMNDALRFSQQGMTTIFGLAGASLAFYHTAKPEKKAMAKAILLPAIIT
SMLTGITEPIEFTFLFVSPLLWVIHATLTAASQAICDIFTVRPWGASGLIEFLIYNLPLPVSLTRWPGYVLIGIGQFAVY
YVIFRTLVVKLNLKTPGREDDENVKLYSKAEYRQKVAQPQSVTDDIIRGLGGKENILSVDNCFTRLRVAVRDMARVDDTQ
LKNTGANGVVRNRNEVQVIYGVKVGQVRSRVDNWLAEN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=32.5626204238921, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1787343, Length=517, Percent_Identity=32.495164410058, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1786894, Length=521, Percent_Identity=32.2456813819578, Blast_Score=203, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57229; Mature: 57098

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEIRQRILENMQKFSRAMIGAVLFLPVIGLILALSSVLTNPTLIAETSFLHQLGQMLGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFWPLFGNLGLLFCVGISYGLAKDKKTEVALVSVMCFIMFLGANHSWLEHTHGLAEKING
HHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
EYYGTGQTQLLGFVVVDMGVFLGIILGCTIAWVHNKVSAIELPGALSMYGGAKLTLVAMT
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCCEEEEHHHH
PVVIFYAIAFTWIWPFMTHGISALIGFMKNAGVAGVFVYGFFEKFLIPTGLHHFVWSPFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCEE
LTQIGGTLNVDGQVVSGTQAIFLAYMRHPDLTPVMNDALRFSQQGMTTIFGLAGASLAFY
EEECCCEEECCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEE
HTAKPEKKAMAKAILLPAIITSMLTGITEPIEFTFLFVSPLLWVIHATLTAASQAICDIF
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVRPWGASGLIEFLIYNLPLPVSLTRWPGYVLIGIGQFAVYYVIFRTLVVKLNLKTPGRE
EECCCCHHHHHHHHHHCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHEEECCCCCCC
DDENVKLYSKAEYRQKVAQPQSVTDDIIRGLGGKENILSVDNCFTRLRVAVRDMARVDDT
CCCCEEEEHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHH
QLKNTGANGVVRNRNEVQVIYGVKVGQVRSRVDNWLAEN
HHHCCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]