Click here to switch to the map view.

The map label for this gene is gltS [H]

Identifier: 238897114

GI number: 238897114

Start: 5108914

End: 5110116

Strand: Reverse

Name: gltS [H]

Synonym: KP1_5371

Alternate gene names: 238897114

Gene position: 5110116-5108914 (Counterclockwise)

Preceding gene: 238897119

Following gene: 238897111

Centisome position: 97.36

GC content: 60.68

Gene sequence:

>1203_bases
ATGTTTCATCTCGATACCTTATCGACGCTCGTTGCCGCAACGCTCGTGCTGTTACTCGGCAGAAAACTCGTACAAACCGT
TCCCTTCCTTAAGAAATACACTATTCCTGAACCCGTTGCCGGCGGTCTGCTGGTGGCGCTGGCGCTGCTGGCGCTGAAAA
AAAGCATGGATATCGAAATTGATTTCGATATGAGTCTGAAAGATCCGCTGATGCTGGCGTTCTTCGCCACCATCGGTCTT
AACGCCAACCTCGCCAGCCTGCGGGCCGGCGGCAAGGTGCTGGGCACTTTCCTGATCGTGGTGGTTGGCCTGCTGCTGCT
GCAGAACGCCCTCGGTATCGGCATGGCGACGCTGCTGGGGCTGGATCCGCTAATGGGTCTGCTGGCCGGGTCGATTACCT
TATCCGGCGGCCACGGCACCGGGGCGGCGTGGAGTAAGCTGTTCGTTGAGCGCTACGGTTTTGCCAACGCCACCGAGGTG
GCGATGGCCTGCGCGACTTTCGGCCTGGTGCTGGGCGGCCTGATCGGCGGCCCGGTGGCGCGTTATCTGGTGAAGCACTC
TTCCTCACCGGACGGGACACCGGACGATCAGGTGGCGCCAACCGCCTTTGAAAAGCCGGACGTGGGGCGGGTGATCACCT
CGCTGGTGCTGATCGAAAGTATCGCCCTGATCGCCATCTGTCTGACGCTGGGCAAGGTGGTTGCGCAACTGCTGGCGGGG
AGCGTCTTCGAGCTGCCGACCTTCGTCTGCGTGCTGTTTATCGGCGTGATCCTCAGCAACAGCCTGGCGCTGGCGGGGTT
GTATCGGGTGTTCGATCGCGCGGTATCGGTGTTGGGCAACGTCAGCCTGTCGCTGTTCCTCGCCATGGCGCTGATGAGCC
TCAAGCTGTGGGAGTTGGCCTCGCTGGCGCTGCCGATGATTATTATCCTGGCGGTGCAGGCGCTGGCGATGGCGCTGTAT
GCGGTGTTCGTCACCTATCGGATGATGGGCAAAAACTACGATGCCGCGGTGCTGGCAGCCGGGCATTGCGGATTTGGCCT
GGGGGCAACGCCGACGGCGATCGCCAATATGCAGGCGATTACCGACCGTTTCGGGCCATCGCATATGGCCTTCCTGGTAG
TGCCGATGGTGGGGGCGTTCTTTATCGATATCGTCAACGCGCTGGTGATTAAGCTGTACCTGCTGCTGCCGATGTTTGGT
TGA

Upstream 100 bases:

>100_bases
TTCTGCGTAAAATCCCCCTCTGACTCCTCATGATGAGAAGCTAAAGACACCAGGAATATCGTCGCGTGTGAATGGATCAT
GCGCCCATAAGGAGCTTTTT

Downstream 100 bases:

>100_bases
TAAAAAACCCGGAGGCGGTGCTGCGCACCTGTCCGGGCTACAAGATCGTGCTGTTTGGGGTTTTGTAGCCCGGCTAAGGC
GTTTACGCCGCAAGCCGGGA

Product: glutamate:Na+ symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFHLDTLSTLVAATLVLLLGRKLVQTVPFLKKYTIPEPVAGGLLVALALLALKKSMDIEIDFDMSLKDPLMLAFFATIGL
NANLASLRAGGKVLGTFLIVVVGLLLLQNALGIGMATLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFVERYGFANATEV
AMACATFGLVLGGLIGGPVARYLVKHSSSPDGTPDDQVAPTAFEKPDVGRVITSLVLIESIALIAICLTLGKVVAQLLAG
SVFELPTFVCVLFIGVILSNSLALAGLYRVFDRAVSVLGNVSLSLFLAMALMSLKLWELASLALPMIIILAVQALAMALY
AVFVTYRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLLLPMFG

Sequences:

>Translated_400_residues
MFHLDTLSTLVAATLVLLLGRKLVQTVPFLKKYTIPEPVAGGLLVALALLALKKSMDIEIDFDMSLKDPLMLAFFATIGL
NANLASLRAGGKVLGTFLIVVVGLLLLQNALGIGMATLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFVERYGFANATEV
AMACATFGLVLGGLIGGPVARYLVKHSSSPDGTPDDQVAPTAFEKPDVGRVITSLVLIESIALIAICLTLGKVVAQLLAG
SVFELPTFVCVLFIGVILSNSLALAGLYRVFDRAVSVLGNVSLSLFLAMALMSLKLWELASLALPMIIILAVQALAMALY
AVFVTYRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLLLPMFG
>Mature_400_residues
MFHLDTLSTLVAATLVLLLGRKLVQTVPFLKKYTIPEPVAGGLLVALALLALKKSMDIEIDFDMSLKDPLMLAFFATIGL
NANLASLRAGGKVLGTFLIVVVGLLLLQNALGIGMATLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFVERYGFANATEV
AMACATFGLVLGGLIGGPVARYLVKHSSSPDGTPDDQVAPTAFEKPDVGRVITSLVLIESIALIAICLTLGKVVAQLLAG
SVFELPTFVCVLFIGVILSNSLALAGLYRVFDRAVSVLGNVSLSLFLAMALMSLKLWELASLALPMIIILAVQALAMALY
AVFVTYRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLLLPMFG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=399, Percent_Identity=86.9674185463659, Blast_Score=631, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 41945; Mature: 41945

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHLDTLSTLVAATLVLLLGRKLVQTVPFLKKYTIPEPVAGGLLVALALLALKKSMDIEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEE
DFDMSLKDPLMLAFFATIGLNANLASLRAGGKVLGTFLIVVVGLLLLQNALGIGMATLLG
ECCCCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPLMGLLAGSITLSGGHGTGAAWSKLFVERYGFANATEVAMACATFGLVLGGLIGGPVA
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYLVKHSSSPDGTPDDQVAPTAFEKPDVGRVITSLVLIESIALIAICLTLGKVVAQLLAG
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVFELPTFVCVLFIGVILSNSLALAGLYRVFDRAVSVLGNVSLSLFLAMALMSLKLWELA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPMIIILAVQALAMALYAVFVTYRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCHHHHHHHHHH
TDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLLLPMFG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFHLDTLSTLVAATLVLLLGRKLVQTVPFLKKYTIPEPVAGGLLVALALLALKKSMDIEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEE
DFDMSLKDPLMLAFFATIGLNANLASLRAGGKVLGTFLIVVVGLLLLQNALGIGMATLLG
ECCCCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDPLMGLLAGSITLSGGHGTGAAWSKLFVERYGFANATEVAMACATFGLVLGGLIGGPVA
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYLVKHSSSPDGTPDDQVAPTAFEKPDVGRVITSLVLIESIALIAICLTLGKVVAQLLAG
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVFELPTFVCVLFIGVILSNSLALAGLYRVFDRAVSVLGNVSLSLFLAMALMSLKLWELA
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPMIIILAVQALAMALYAVFVTYRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCHHHHHHHHHH
TDRFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLLLPMFG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2254324; 2017136; 7686882; 9278503; 1544582 [H]