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The map label for this gene is clcB [H]

Identifier: 238897095

GI number: 238897095

Start: 5088257

End: 5089561

Strand: Reverse

Name: clcB [H]

Synonym: KP1_5348

Alternate gene names: 238897095

Gene position: 5089561-5088257 (Counterclockwise)

Preceding gene: 238897097

Following gene: 238897091

Centisome position: 96.97

GC content: 61.3

Gene sequence:

>1305_bases
ATGTTTAGGTCTCGTCCTTTATTCTTTTATTTTTCCTTTTCAAGGCCTGAGAAAATGAGCGTCGCCGCCGGGAATAAAAA
TCATCTGATCCGCCTGATAGCCGTGGTATTAACCGGGATTCTGGCCGGTCTGTCCGGCATGGTTTTGGCACTAATTTTAC
ACGCGATTCAGCACCTGGCTTTTGGTTACAGTTATGGGCAGATCGTCGGTTCGGTGTCATTTTTACAGGGCGTCACGGAG
TCGTCCTGGCCACGCCGCATCGTGGCAATCGTGGCCGGCGGCGCCGTCGCCGGATTTGGCTGGTGGCTGCTTGGTCGCTA
CGGGCAGAGGCGGGTTTCCATTGCGGCGGCGGTGGCCAACCCCTGCGTACCCATGCCCGCGGGCACCACGACGATCCACG
CGCTGCTGCAGATCGTCACCGTAGCGCTGGGCTCCCCGCTTGGCCGCGAAGTGGCGCCCCGGGAAATGGGCGCGCTGGGG
GCGGGGATGGTGGCGCGTAAGCTGCGCCTGCTGGAAGATGAAACCCGCACGCTGATTGCCTGTGGGGCGGGCGCGGGTCT
GGCGGCGGTCTATAACGTCCCGCTGGCCGGGGCGTTGTTCAGCCTTGAGGTCATGCTGCTGTCGTTTAGCTGGGAAAAAA
CGCTGGCGGCGATGATGACCTCGGCGATTGCCGCCTGGACGGCCACCCTGGGGTTAGGGGATGAATCGCAATACCATTTT
GTTTCCAGCGCACTTCCGCACACCTTTCTCTGGTGGGCGATTCTGGCGGGCCCGATTCTTGGCACCGGCGCCTGGCTCTT
TCGCAAAGCGACCAGCGCGGCGCGTTCACGCGCGCGAAGTAACTGGCAGATGCCGGTGTTCTGTCTGCTGGAGTTTTCTC
TTCTTGCCATCCTGAGTCTTTATTTCCCCGAGCTTCCGGGCAATGGCAAGGGTCCAATGCAGCTGGCGCTCAGCGACGTG
CTACCTCTCTCCATGGTCGCTGTCCTGTTAGTATTGAAGATGGTGGTGATTCTGGCGGTGCTGCGCGGCGGCGCGGAGGG
TGGATTGTTAACCCCAGGGCTGGCGGTGGGCGGATTGGTCAGCCTGCTGCTCTGCGCGCTCTGGCAGCTCGGCTTCCCTG
GCGGTGATAAAAGCAGCTTCGCTGTGGTGGGGGCGGCCGCGTTTCTCGCCGCCTCCATGCAGATGCCGTTGACCGCAGTG
GCGCTGGTGATGGAGTTTACCCACATGGATCACAGCTATCTGGCTCCGGCGCTGCTGTGCGCGGCAGGGGCGTTTTTAAC
CTGCCGGGCGCTGGATAAAAAATAG

Upstream 100 bases:

>100_bases
ATTTAAAGGTTGATTGATTTTTTAGGGATTTTTATTGATTAGAAAAAGTAATGCTAAGTGAAGCGATGGGTATCACTATC
GAAAAGACTATGATTACGCA

Downstream 100 bases:

>100_bases
GCTTACCGAGCCGCGGTGAAAGTCAGGGAGGGGCCCGTTGATCCTGAAAGTAAAATCAGCCGCGTTTTTCCCTGATGGTT
GCCTCATGGTTAATAAGCCA

Product: putative voltage-gated Clc-type chloride channel

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MFRSRPLFFYFSFSRPEKMSVAAGNKNHLIRLIAVVLTGILAGLSGMVLALILHAIQHLAFGYSYGQIVGSVSFLQGVTE
SSWPRRIVAIVAGGAVAGFGWWLLGRYGQRRVSIAAAVANPCVPMPAGTTTIHALLQIVTVALGSPLGREVAPREMGALG
AGMVARKLRLLEDETRTLIACGAGAGLAAVYNVPLAGALFSLEVMLLSFSWEKTLAAMMTSAIAAWTATLGLGDESQYHF
VSSALPHTFLWWAILAGPILGTGAWLFRKATSAARSRARSNWQMPVFCLLEFSLLAILSLYFPELPGNGKGPMQLALSDV
LPLSMVAVLLVLKMVVILAVLRGGAEGGLLTPGLAVGGLVSLLLCALWQLGFPGGDKSSFAVVGAAAFLAASMQMPLTAV
ALVMEFTHMDHSYLAPALLCAAGAFLTCRALDKK

Sequences:

>Translated_434_residues
MFRSRPLFFYFSFSRPEKMSVAAGNKNHLIRLIAVVLTGILAGLSGMVLALILHAIQHLAFGYSYGQIVGSVSFLQGVTE
SSWPRRIVAIVAGGAVAGFGWWLLGRYGQRRVSIAAAVANPCVPMPAGTTTIHALLQIVTVALGSPLGREVAPREMGALG
AGMVARKLRLLEDETRTLIACGAGAGLAAVYNVPLAGALFSLEVMLLSFSWEKTLAAMMTSAIAAWTATLGLGDESQYHF
VSSALPHTFLWWAILAGPILGTGAWLFRKATSAARSRARSNWQMPVFCLLEFSLLAILSLYFPELPGNGKGPMQLALSDV
LPLSMVAVLLVLKMVVILAVLRGGAEGGLLTPGLAVGGLVSLLLCALWQLGFPGGDKSSFAVVGAAAFLAASMQMPLTAV
ALVMEFTHMDHSYLAPALLCAAGAFLTCRALDKK
>Mature_434_residues
MFRSRPLFFYFSFSRPEKMSVAAGNKNHLIRLIAVVLTGILAGLSGMVLALILHAIQHLAFGYSYGQIVGSVSFLQGVTE
SSWPRRIVAIVAGGAVAGFGWWLLGRYGQRRVSIAAAVANPCVPMPAGTTTIHALLQIVTVALGSPLGREVAPREMGALG
AGMVARKLRLLEDETRTLIACGAGAGLAAVYNVPLAGALFSLEVMLLSFSWEKTLAAMMTSAIAAWTATLGLGDESQYHF
VSSALPHTFLWWAILAGPILGTGAWLFRKATSAARSRARSNWQMPVFCLLEFSLLAILSLYFPELPGNGKGPMQLALSDV
LPLSMVAVLLVLKMVVILAVLRGGAEGGLLTPGLAVGGLVSLLLCALWQLGFPGGDKSSFAVVGAAAFLAASMQMPLTAV
ALVMEFTHMDHSYLAPALLCAAGAFLTCRALDKK

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 45787; Mature: 45787

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSRPLFFYFSFSRPEKMSVAAGNKNHLIRLIAVVLTGILAGLSGMVLALILHAIQHLA
CCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSYGQIVGSVSFLQGVTESSWPRRIVAIVAGGAVAGFGWWLLGRYGQRRVSIAAAVAN
HCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHC
PCVPMPAGTTTIHALLQIVTVALGSPLGREVAPREMGALGAGMVARKLRLLEDETRTLIA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
CGAGAGLAAVYNVPLAGALFSLEVMLLSFSWEKTLAAMMTSAIAAWTATLGLGDESQYHF
ECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VSSALPHTFLWWAILAGPILGTGAWLFRKATSAARSRARSNWQMPVFCLLEFSLLAILSL
HHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YFPELPGNGKGPMQLALSDVLPLSMVAVLLVLKMVVILAVLRGGAEGGLLTPGLAVGGLV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
SLLLCALWQLGFPGGDKSSFAVVGAAAFLAASMQMPLTAVALVMEFTHMDHSYLAPALLC
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
AAGAFLTCRALDKK
HHHHHHHHHCCCCC
>Mature Secondary Structure
MFRSRPLFFYFSFSRPEKMSVAAGNKNHLIRLIAVVLTGILAGLSGMVLALILHAIQHLA
CCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSYGQIVGSVSFLQGVTESSWPRRIVAIVAGGAVAGFGWWLLGRYGQRRVSIAAAVAN
HCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHC
PCVPMPAGTTTIHALLQIVTVALGSPLGREVAPREMGALGAGMVARKLRLLEDETRTLIA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
CGAGAGLAAVYNVPLAGALFSLEVMLLSFSWEKTLAAMMTSAIAAWTATLGLGDESQYHF
ECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VSSALPHTFLWWAILAGPILGTGAWLFRKATSAARSRARSNWQMPVFCLLEFSLLAILSL
HHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
YFPELPGNGKGPMQLALSDVLPLSMVAVLLVLKMVVILAVLRGGAEGGLLTPGLAVGGLV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
SLLLCALWQLGFPGGDKSSFAVVGAAAFLAASMQMPLTAVALVMEFTHMDHSYLAPALLC
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
AAGAFLTCRALDKK
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA