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The map label for this gene is coaD [H]

Identifier: 238897075

GI number: 238897075

Start: 5071800

End: 5072279

Strand: Direct

Name: coaD [H]

Synonym: KP1_5326

Alternate gene names: 238897075

Gene position: 5071800-5072279 (Clockwise)

Preceding gene: 238897074

Following gene: 238897080

Centisome position: 96.63

GC content: 55.62

Gene sequence:

>480_bases
ATGAGCACAAAAGCGATCTATCCGGGTACCTTCGACCCCATCACCAACGGTCATATCGATATTGTCACCCGCGCGGCAAG
TATGTTCGATAAAGTGGTGCTGGCTATCGCCGCCAGCCCGAGTAAAAAGCCGATGTTCAGCCTTGATGAGCGCATTGCGC
TGGCAGAGCAGGCGACGGCCCACCTGGTGAACGTGGAGGTTATCGGCTTCAGTGATTTAATGGCCAATTTCGCGCGCGCG
CAGCAGGCCAATATCCTGATCCGCGGCCTGCGGGCGGTGGCGGATTTCGAGTATGAGATGCAGCTGGCTCATATGAACCG
CCACCTGATGCCCACCCTTGAGAGCGTGTTTCTGATGCCGTGCAAAGAGTGGTCGTTTATCTCTTCCTCACTGGTGAAGG
AAGTGGCGCGCCACCAGGGCGACGTTTCTCACTTTCTGCCAGCTAATGTGCATCAGGCGCTGTTGAATAAGCTGAAGTAA

Upstream 100 bases:

>100_bases
AACAGGGATGGTTACTGGCGGTGGTCAACGCGCAGTATACGTTTACGAAATATACCGAGCTGTGGGCGCTGAGCCACGGC
TACTCGGAGAAAGAGTCATC

Downstream 100 bases:

>100_bases
CGCATCTGCCGGGACATGAGCCACATTGGCTGGCGCAGCACTGCGCCGCTGGGTCATTCACACCGGCTCTATCCCGGTCT
TTGTGCCAGATGGCGCTACG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSTKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATAHLVNVEVIGFSDLMANFARA
QQANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMPCKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK

Sequences:

>Translated_159_residues
MSTKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATAHLVNVEVIGFSDLMANFARA
QQANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMPCKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK
>Mature_158_residues
STKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATAHLVNVEVIGFSDLMANFARAQ
QANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMPCKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=85.4430379746835, Blast_Score=288, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17663; Mature: 17532

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
HLVNVEVIGFSDLMANFARAQQANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMP
HEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
CKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK
CCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
HLVNVEVIGFSDLMANFARAQQANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMP
HEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
CKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK
CCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA