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The map label for this gene is yhiP [H]

Identifier: 238896959

GI number: 238896959

Start: 4932383

End: 4933855

Strand: Direct

Name: yhiP [H]

Synonym: KP1_5201

Alternate gene names: 238896959

Gene position: 4932383-4933855 (Clockwise)

Preceding gene: 238896958

Following gene: 238896963

Centisome position: 93.98

GC content: 57.09

Gene sequence:

>1473_bases
ATGAATACAACTGCACCTACGGGCTTGCTGCAGCAACCTCGTCCGTTCTTTATGATCTTCTTTGTGGAGCTCTGGGAACG
TTTTGGCTATTACGGCGTTCAGGGGATCCTGGCGGTCTTCTTTGTTAAACAGCTGGGCTTCTCTCAGGAACAGGCCTTTA
TCACCTTCGGCGCCTTCGCGGCGCTGGTTTACGGGCTGATCTCCATCGGCGGCTACGTGGGCGACCATTTGCTGGGGACC
AAACGCACGCTGGTGCTCGGCGCCATTGTGCTGGCTATCGGCTACTTTATGACCGGGATGTCGCTGCTGAAACCGCAGCT
GATCTTTATCGCTCTCGGCACCATCGCCGTCGGCAACGGTTTGTTTAAAGCCAACCCGGCGAGCCTGCTCTCCAAATGCT
ATCCGCCGAAGGATGCCCGTCTCGACGGGGCATTTACCCTGTTCTATATGTCGATAAACATCGGTTCGCTGCTGTCGCTG
TCGCTGGCGCCGGTGATCGCCGAAAAATTTGGCTACGCGGTAACCTATAACCTGTGCGGCGCGGGGCTGATTATCGCGCT
GCTGGTCTACTTCGCCTGCCGCGGGATGGTGAAAGATATTGGCTCCGAGCCGGATCATCGCCCCCTCAGCCTACGCAATC
TGGCGCTGGTGCTGGCCGGTACGGTGGTAATGATTTTTCTCTGCGCCTGGCTGATGCATAACGTGATGATCGCCAACCTG
GTGCTGATTGTTCTGTCGGTCGTGGTTATTGCGTTCTTTTTCCGTGAGGCGTTTCGCCTCGATAAAACTGGACGCAACAA
AATGTTCGTCGCCTTTATTCTGATGATCGAGGCGGTGCTGTTTTACATTCTGTATGCCCAGATGCCGACCTCGCTGAACT
TCTTCGCCATCAACAACGTCCATCATGAGATCCTTGGCTTTACCATCAACCCGGTCAGCTTCCAGGCGCTGAATCCCTTC
TGGGTAGTGGTCGCCAGCCCGGTGCTGGCGGCGATCTACACCCATCTCGGTCATAAGGGTAAAGACCTGACCATGCCGGT
GAAATTTACCCTCGGGATGTTCCTCTGCGCGCTGGGCTTTCTCACCGCCGCAGCCGCCGGGATGTGGTTCGCCGACGCCC
AGGGGTTAACCTCGCCGTGGTTTATTGTGCTGGTCTATCTGTTCCAGAGTCTGGGGGAACTGTTAATCAGCGCTCTGGGG
CTGGCGATGGTTGCCGCGCTGGTGCCGCAGCATCTGATGGGCTTTATTCTGGGGATGTGGTTTCTGACCCAGGCCGCCGC
TTTCCTGCTGGGCGGCTATGTGGCGACCTTTACCGCGGTGCCGGAAAACATCACCGACCCGCTGCAGACCCTGCCGGTCT
ACACCAATGTGTTCAGTAAAATTGGCCTGGTGACGCTGGGCGTCACGGTGGTAATGGCGCTGATGGTGCCGTGGCTGAAC
CGGATGATTAATACCCCGGCCAGCGCCGAATAA

Upstream 100 bases:

>100_bases
ATAAGCCAATAACCGCAGCATGGCGAGTTATCAGACATTTTCGGCGCGTTCTGGCATACGCGTTCATACTTTTTGGGAAA
GTAATACAAGGCGAAGGAAT

Downstream 100 bases:

>100_bases
CCGTTTGAGATGGCCGATCCGCTGGCGCCGTTTGTTTAAATATTGCGGTTCCCGGCTCGCGCTACAATTTGGTAGCCCGG
ATAAGGCGCTTTGCCCGCTA

Product: inner membrane transporter YhiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLKPQLIFIALGTIAVGNGLFKANPASLLSKCYPPKDARLDGAFTLFYMSINIGSLLSL
SLAPVIAEKFGYAVTYNLCGAGLIIALLVYFACRGMVKDIGSEPDHRPLSLRNLALVLAGTVVMIFLCAWLMHNVMIANL
VLIVLSVVVIAFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFTINPVSFQALNPF
WVVVASPVLAAIYTHLGHKGKDLTMPVKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPVYTNVFSKIGLVTLGVTVVMALMVPWLN
RMINTPASAE

Sequences:

>Translated_490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLKPQLIFIALGTIAVGNGLFKANPASLLSKCYPPKDARLDGAFTLFYMSINIGSLLSL
SLAPVIAEKFGYAVTYNLCGAGLIIALLVYFACRGMVKDIGSEPDHRPLSLRNLALVLAGTVVMIFLCAWLMHNVMIANL
VLIVLSVVVIAFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFTINPVSFQALNPF
WVVVASPVLAAIYTHLGHKGKDLTMPVKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPVYTNVFSKIGLVTLGVTVVMALMVPWLN
RMINTPASAE
>Mature_490_residues
MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGT
KRTLVLGAIVLAIGYFMTGMSLLKPQLIFIALGTIAVGNGLFKANPASLLSKCYPPKDARLDGAFTLFYMSINIGSLLSL
SLAPVIAEKFGYAVTYNLCGAGLIIALLVYFACRGMVKDIGSEPDHRPLSLRNLALVLAGTVVMIFLCAWLMHNVMIANL
VLIVLSVVVIAFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFTINPVSFQALNPF
WVVVASPVLAAIYTHLGHKGKDLTMPVKFTLGMFLCALGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALG
LAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPVYTNVFSKIGLVTLGVTVVMALMVPWLN
RMINTPASAE

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=233, Percent_Identity=27.4678111587983, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4827008, Length=389, Percent_Identity=23.1362467866324, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789911, Length=488, Percent_Identity=88.7295081967213, Blast_Score=890, Evalue=0.0,
Organism=Escherichia coli, GI1787922, Length=472, Percent_Identity=52.3305084745763, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1786927, Length=461, Percent_Identity=25.8134490238612, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1790572, Length=483, Percent_Identity=26.5010351966874, Blast_Score=163, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17541704, Length=380, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569141, Length=202, Percent_Identity=27.2277227722772, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571098, Length=213, Percent_Identity=25.8215962441315, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571102, Length=213, Percent_Identity=25.8215962441315, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571100, Length=213, Percent_Identity=25.8215962441315, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639583, Length=175, Percent_Identity=30.8571428571429, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639585, Length=164, Percent_Identity=31.7073170731707, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639581, Length=164, Percent_Identity=31.7073170731707, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53471; Mature: 53471

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCC
>Mature Secondary Structure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HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]