| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is nikD [H]
Identifier: 238896950
GI number: 238896950
Start: 4924208
End: 4924972
Strand: Direct
Name: nikD [H]
Synonym: KP1_5192
Alternate gene names: 238896950
Gene position: 4924208-4924972 (Clockwise)
Preceding gene: 238896949
Following gene: 238896951
Centisome position: 93.82
GC content: 66.01
Gene sequence:
>765_bases ATGCCGCAGAAGATCCAACTGGAACAGATCTCGCTTGCCGCTGACCGACCGCTGGTCAGCGACGTCTCCTTCACCCTGCG CCGCGGCCAGGTGCTGGCGCTGCTCGGCAGCAGTGGTTGCGGAAAATCGCTGACCTGCGCCGCCGCGCTGGGCCTGCTGC CGCCCGGCGTCAGGCAAACCGCCGGCCGGGTGCTTCTCGACGGCATTCCGGTGCACGGCGAACAGCTGCGCGGGGCGACC ATCGCCACCATCATGCAGAACCCGCGCAGCGCCTTTAACCCGCTGCATACCATGGCCGCGCACGCCCGGGAAACCTGCCG GGCAGCGGGTCGTGAAGCGAATGACGCCGTGCTGCTGGCAGCGATGGAGGAGGTCGGTCTGGACAATCCGCGGGCGCTGC TGAAGCGCTACCCTTTTGAAATGAGCGGGGGCATGCTGCAACGGATGATGGTCGCTCTCGCCCTGCTCAGCCGCGCGCCC TTTATCATCGCCGACGAGCCGACGACCGATCTCGATACCATCGCCCAGGCGCGCATCCTCGACCTGCTGGCGGATATTGT CGCCAGGCGCGGTCTGGGACTGCTGCTGGTGACGCATGACATGGGCGTCGTGGCGCGGCTGGCGCATCACGTAACGGTGA TGGAGAACGGTCGCCTCGTTGAACACTGCGATGTGAATACGCTATTTAGCGCCCCGCGGCACCCGCTCAGCCAGCGCCTG CTGGCCGCGCATCTGGCGTTATACGGTCTGGAGAAAACACCATGA
Upstream 100 bases:
>100_bases CGGGGCTGGCGCTGTTCATCAGCGTGATGGCTTTTAACCTGCTGGGCGACGCGCTGCGCGATCGTCTCGATCCCCACCTG ATCGCGGAGCATAGCCACTG
Downstream 100 bases:
>100_bases ATTTACTCAGCGCTACCGGGGTGAGTCACGATTATCCTCACCACGGCAGGGTCCTGCATGCGATCCATCTCGCCATCGCC CCTGGCGAAACGGTGGCCCT
Product: nickel transporter ATP-binding protein NikD
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MPQKIQLEQISLAADRPLVSDVSFTLRRGQVLALLGSSGCGKSLTCAAALGLLPPGVRQTAGRVLLDGIPVHGEQLRGAT IATIMQNPRSAFNPLHTMAAHARETCRAAGREANDAVLLAAMEEVGLDNPRALLKRYPFEMSGGMLQRMMVALALLSRAP FIIADEPTTDLDTIAQARILDLLADIVARRGLGLLLVTHDMGVVARLAHHVTVMENGRLVEHCDVNTLFSAPRHPLSQRL LAAHLALYGLEKTP
Sequences:
>Translated_254_residues MPQKIQLEQISLAADRPLVSDVSFTLRRGQVLALLGSSGCGKSLTCAAALGLLPPGVRQTAGRVLLDGIPVHGEQLRGAT IATIMQNPRSAFNPLHTMAAHARETCRAAGREANDAVLLAAMEEVGLDNPRALLKRYPFEMSGGMLQRMMVALALLSRAP FIIADEPTTDLDTIAQARILDLLADIVARRGLGLLLVTHDMGVVARLAHHVTVMENGRLVEHCDVNTLFSAPRHPLSQRL LAAHLALYGLEKTP >Mature_253_residues PQKIQLEQISLAADRPLVSDVSFTLRRGQVLALLGSSGCGKSLTCAAALGLLPPGVRQTAGRVLLDGIPVHGEQLRGATI ATIMQNPRSAFNPLHTMAAHARETCRAAGREANDAVLLAAMEEVGLDNPRALLKRYPFEMSGGMLQRMMVALALLSRAPF IIADEPTTDLDTIAQARILDLLADIVARRGLGLLLVTHDMGVVARLAHHVTVMENGRLVEHCDVNTLFSAPRHPLSQRLL AAHLALYGLEKTP
Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI105990541, Length=217, Percent_Identity=30.8755760368664, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI116734710, Length=222, Percent_Identity=27.4774774774775, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI21536376, Length=218, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI42741659, Length=219, Percent_Identity=28.7671232876712, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI27436953, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI153792144, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI156105685, Length=218, Percent_Identity=28.8990825688073, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1789890, Length=251, Percent_Identity=66.9322709163347, Blast_Score=338, Evalue=2e-94, Organism=Escherichia coli, GI1788506, Length=243, Percent_Identity=41.9753086419753, Blast_Score=174, Evalue=4e-45, Organism=Escherichia coli, GI1789963, Length=239, Percent_Identity=34.7280334728033, Blast_Score=158, Evalue=3e-40, Organism=Escherichia coli, GI145693107, Length=244, Percent_Identity=38.1147540983607, Blast_Score=155, Evalue=2e-39, Organism=Escherichia coli, GI48994883, Length=239, Percent_Identity=36.4016736401674, Blast_Score=137, Evalue=8e-34, Organism=Escherichia coli, GI1787759, Length=250, Percent_Identity=34.8, Blast_Score=134, Evalue=4e-33, Organism=Escherichia coli, GI1789962, Length=228, Percent_Identity=35.9649122807018, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1787548, Length=242, Percent_Identity=29.3388429752066, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1787500, Length=234, Percent_Identity=33.7606837606838, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787758, Length=229, Percent_Identity=31.8777292576419, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1787547, Length=235, Percent_Identity=30.2127659574468, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI48994997, Length=229, Percent_Identity=32.3144104803493, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1786398, Length=239, Percent_Identity=34.3096234309623, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=33.4905660377358, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1790162, Length=240, Percent_Identity=26.25, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87081791, Length=238, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789032, Length=222, Percent_Identity=27.4774774774775, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786563, Length=226, Percent_Identity=29.2035398230088, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786872, Length=219, Percent_Identity=29.2237442922374, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787112, Length=209, Percent_Identity=29.1866028708134, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=31.7535545023697, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788165, Length=207, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786703, Length=216, Percent_Identity=31.9444444444444, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1786253, Length=221, Percent_Identity=28.5067873303167, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1786319, Length=232, Percent_Identity=26.2931034482759, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=27.5423728813559, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI48994943, Length=206, Percent_Identity=28.6407766990291, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788225, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789873, Length=224, Percent_Identity=26.7857142857143, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1786803, Length=250, Percent_Identity=25.6, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1790739, Length=226, Percent_Identity=27.8761061946903, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=26.4069264069264, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787712, Length=253, Percent_Identity=24.901185770751, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787089, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787370, Length=231, Percent_Identity=23.3766233766234, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788644, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI48995001, Length=254, Percent_Identity=28.3464566929134, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789991, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787164, Length=213, Percent_Identity=30.0469483568075, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1789586, Length=245, Percent_Identity=25.7142857142857, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1786345, Length=211, Percent_Identity=28.436018957346, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1788761, Length=215, Percent_Identity=28.8372093023256, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17510237, Length=227, Percent_Identity=28.6343612334802, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17558664, Length=215, Percent_Identity=29.3023255813954, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI71983516, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71983510, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71983523, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17569145, Length=217, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI115533592, Length=258, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17569143, Length=248, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI212646699, Length=227, Percent_Identity=25.9911894273128, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71996550, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17541710, Length=216, Percent_Identity=26.8518518518519, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24666092, Length=204, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24659289, Length=215, Percent_Identity=28.8372093023256, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI17136662, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR015857 - InterPro: IPR003593 - InterPro: IPR014138 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: =3.6.3.24 [H]
Molecular weight: Translated: 27289; Mature: 27158
Theoretical pI: Translated: 8.37; Mature: 8.37
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 5.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPQKIQLEQISLAADRPLVSDVSFTLRRGQVLALLGSSGCGKSLTCAAALGLLPPGVRQT CCCCCCHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHH AGRVLLDGIPVHGEQLRGATIATIMQNPRSAFNPLHTMAAHARETCRAAGREANDAVLLA HCCEEECCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEE AMEEVGLDNPRALLKRYPFEMSGGMLQRMMVALALLSRAPFIIADEPTTDLDTIAQARIL EHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH DLLADIVARRGLGLLLVTHDMGVVARLAHHVTVMENGRLVEHCDVNTLFSAPRHPLSQRL HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHEECCCCEEEECCCHHHHCCCCCHHHHHH LAAHLALYGLEKTP HHHHHHHHCCCCCC >Mature Secondary Structure PQKIQLEQISLAADRPLVSDVSFTLRRGQVLALLGSSGCGKSLTCAAALGLLPPGVRQT CCCCCHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHH AGRVLLDGIPVHGEQLRGATIATIMQNPRSAFNPLHTMAAHARETCRAAGREANDAVLLA HCCEEECCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEE AMEEVGLDNPRALLKRYPFEMSGGMLQRMMVALALLSRAPFIIADEPTTDLDTIAQARIL EHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH DLLADIVARRGLGLLLVTHDMGVVARLAHHVTVMENGRLVEHCDVNTLFSAPRHPLSQRL HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHEECCCCEEEECCCHHHHCCCCCHHHHHH LAAHLALYGLEKTP HHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]