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The map label for this gene is ftsY [H]

Identifier: 238896927

GI number: 238896927

Start: 4901241

End: 4902764

Strand: Reverse

Name: ftsY [H]

Synonym: KP1_5167

Alternate gene names: 238896927

Gene position: 4902764-4901241 (Counterclockwise)

Preceding gene: 238896930

Following gene: 238896926

Centisome position: 93.41

GC content: 58.53

Gene sequence:

>1524_bases
ATGGCAAAAGAGAAAAAACGTGGCTTCTTTTCCTGGCTGGGCTTTGGACAGAAAGAACAGGCACAGGAAACCGAGACTGA
GCAAAAAGTAGAAGAACAGCAAGCGGTTGCCGAAGAGATACCGGCGGTTGAAACCCCTGCTGAGCCGAGCGCGCCGAAAG
CAGACCCGGAGGCGTTTGCCGAAGACGTCGTCGAAGTGACCGAGACGGTGGTCGAAAGCGAAAAAGCGCACCTCGCGGAG
CCTGCCAGCGCGCAGGAAGAAGAGTGGGTGGAAACGCCTGCTCTGACCGAAGAAACGCCTGTTGTTGAACCGGAGCCCGC
GGTCAGCGAACCGCCTGAACAGCCTGCGGTGGTTGAGCCGCTGGCGGAAGAGGTTATCGCCGAACCGGTGGTGGCGGAAG
CCGTAGCAGAGCAGCCTGTGGAAGGCATCGTTGTCCAGCCGCAGGAGACAGAAGCGCCCGAAGAGGACGCGCCGTTAAGC
GATGAAGAGCTGGAAGCGCAGGCGCTGGCGGCCGAAGCGGCAGAAGAGGCGGCGGTAGTGGTGCCGGCGCCCGAGGACGA
GGCGCCGCTTGAAGCGCTGGCTCAGGAGCAGGAAAAACCGACAAAAGAAGGTTTCTTCGCCCGCCTCAAACGTAGCCTGC
TGAAAACGAAGCAAAATCTCGGTTCCGGATTTATCAGCCTGTTCCGCGGTAAGAAGATCGACGATGATCTGTTTGAAGAG
CTGGAAGAACAGCTGCTGATCGCCGACGTCGGGGTGGAAACCACCCGCAAGATCATTACCAACCTGACGGAAGGCGCCAG
CCGTAAGCAGCTGCGCGATGCGGAAGCGCTGTACGGCCTGCTGAAAGAAGAGATGGGCGAGATTCTCGCCAAAGTAGACG
AGCCGCTGAACGTTGAAGGCAAAACGCCATTTGTTATTCTGATGGTCGGCGTGAACGGGGTGGGGAAAACCACTACCATC
GGCAAGCTGGCGCGTCAGTTTGAACAGCAGGGTAAGTCGGTGATGCTGGCGGCGGGGGATACTTTCCGTGCGGCGGCGGT
GGAACAGCTGCAGGTCTGGGGCCAGCGTAATAATATCCCGGTGATCGCCCAGCACACCGGCGCCGACTCCGCCTCGGTGA
TTTTCGACGCCATTCAGGCGGCGAAGGCGCGCCATGTTGACGTACTGATTGCCGATACCGCCGGGCGTTTGCAGAATAAA
TCGCACCTGATGGAAGAGCTGAAGAAGATTGTCCGGGTAATGAAAAAGCTGGACGTCGACGCGCCGCACGAGGTGATGTT
AACCATTGACGCCAGCACCGGGCAGAATGCTATTAGCCAGGCCAAACTGTTCCATGAGGCGGTAGGTTTGACCGGGATCA
CCCTGACCAAGCTGGACGGTACCGCCAAAGGCGGCGTGATCTTCTCGGTGGCCGATCAGTTCGGCATTCCGATTCGCTAT
ATTGGCGTCGGCGAGCGTATTGAGGATCTGCGTCCGTTTAATGCGGGCGACTTTATTGAGGCACTTTTTGCCCGAGAGGA
TTAA

Upstream 100 bases:

>100_bases
GCGAGTTAAGTTAAGTGATAGACTATCCAACTAATTTCATCATTTTTTCAGCTTCTGATGAAGCTGCGCCATGAATAAAC
AGCGAGGAGTGTGGTCGCAA

Downstream 100 bases:

>100_bases
GAATGATTCGCTTTGAACAAGTCAGCAAAGCCTATCTCGGTGGGAGACAAGCGCTGCAGGGGGTGACCTTCCACCTGCAG
CCGGGCGAGATGGCGTTTCT

Product: cell division protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MAKEKKRGFFSWLGFGQKEQAQETETEQKVEEQQAVAEEIPAVETPAEPSAPKADPEAFAEDVVEVTETVVESEKAHLAE
PASAQEEEWVETPALTEETPVVEPEPAVSEPPEQPAVVEPLAEEVIAEPVVAEAVAEQPVEGIVVQPQETEAPEEDAPLS
DEELEAQALAAEAAEEAAVVVPAPEDEAPLEALAQEQEKPTKEGFFARLKRSLLKTKQNLGSGFISLFRGKKIDDDLFEE
LEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTI
GKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARHVDVLIADTAGRLQNK
SHLMEELKKIVRVMKKLDVDAPHEVMLTIDASTGQNAISQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRY
IGVGERIEDLRPFNAGDFIEALFARED

Sequences:

>Translated_507_residues
MAKEKKRGFFSWLGFGQKEQAQETETEQKVEEQQAVAEEIPAVETPAEPSAPKADPEAFAEDVVEVTETVVESEKAHLAE
PASAQEEEWVETPALTEETPVVEPEPAVSEPPEQPAVVEPLAEEVIAEPVVAEAVAEQPVEGIVVQPQETEAPEEDAPLS
DEELEAQALAAEAAEEAAVVVPAPEDEAPLEALAQEQEKPTKEGFFARLKRSLLKTKQNLGSGFISLFRGKKIDDDLFEE
LEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTI
GKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARHVDVLIADTAGRLQNK
SHLMEELKKIVRVMKKLDVDAPHEVMLTIDASTGQNAISQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRY
IGVGERIEDLRPFNAGDFIEALFARED
>Mature_506_residues
AKEKKRGFFSWLGFGQKEQAQETETEQKVEEQQAVAEEIPAVETPAEPSAPKADPEAFAEDVVEVTETVVESEKAHLAEP
ASAQEEEWVETPALTEETPVVEPEPAVSEPPEQPAVVEPLAEEVIAEPVVAEAVAEQPVEGIVVQPQETEAPEEDAPLSD
EELEAQALAAEAAEEAAVVVPAPEDEAPLEALAQEQEKPTKEGFFARLKRSLLKTKQNLGSGFISLFRGKKIDDDLFEEL
EEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIG
KLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARHVDVLIADTAGRLQNKS
HLMEELKKIVRVMKKLDVDAPHEVMLTIDASTGQNAISQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYI
GVGERIEDLRPFNAGDFIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=276, Percent_Identity=30.4347826086957, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=34.9753694581281, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI295424842, Length=225, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI23308697, Length=225, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=31.2925170068027, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789874, Length=521, Percent_Identity=76.5834932821497, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1788963, Length=298, Percent_Identity=33.5570469798658, Blast_Score=158, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI193206261, Length=319, Percent_Identity=31.6614420062696, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17539958, Length=281, Percent_Identity=27.0462633451957, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=288, Percent_Identity=32.6388888888889, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=225, Percent_Identity=32.8888888888889, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17647949, Length=283, Percent_Identity=30.7420494699647, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641198, Length=333, Percent_Identity=27.9279279279279, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 54956; Mature: 54825

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKKRGFFSWLGFGQKEQAQETETEQKVEEQQAVAEEIPAVETPAEPSAPKADPEAFA
CCCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
EDVVEVTETVVESEKAHLAEPASAQEEEWVETPALTEETPVVEPEPAVSEPPEQPAVVEP
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LAEEVIAEPVVAEAVAEQPVEGIVVQPQETEAPEEDAPLSDEELEAQALAAEAAEEAAVV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
VPAPEDEAPLEALAQEQEKPTKEGFFARLKRSLLKTKQNLGSGFISLFRGKKIDDDLFEE
EECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEG
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIP
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCC
VIAQHTGADSASVIFDAIQAAKARHVDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVD
EEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHCCCC
APHEVMLTIDASTGQNAISQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRY
CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEE
IGVGERIEDLRPFNAGDFIEALFARED
ECCCHHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AKEKKRGFFSWLGFGQKEQAQETETEQKVEEQQAVAEEIPAVETPAEPSAPKADPEAFA
CCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
EDVVEVTETVVESEKAHLAEPASAQEEEWVETPALTEETPVVEPEPAVSEPPEQPAVVEP
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
LAEEVIAEPVVAEAVAEQPVEGIVVQPQETEAPEEDAPLSDEELEAQALAAEAAEEAAVV
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
VPAPEDEAPLEALAQEQEKPTKEGFFARLKRSLLKTKQNLGSGFISLFRGKKIDDDLFEE
EECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEG
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIP
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCC
VIAQHTGADSASVIFDAIQAAKARHVDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVD
EEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHCCCC
APHEVMLTIDASTGQNAISQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRY
CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEE
IGVGERIEDLRPFNAGDFIEALFARED
ECCCHHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]