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The map label for this gene is mocR [H]

Identifier: 238896923

GI number: 238896923

Start: 4896822

End: 4898345

Strand: Direct

Name: mocR [H]

Synonym: KP1_5162

Alternate gene names: 238896923

Gene position: 4896822-4898345 (Clockwise)

Preceding gene: 238896919

Following gene: 238896928

Centisome position: 93.3

GC content: 62.27

Gene sequence:

>1524_bases
TTGCGTTCGCTGGTGGGTGACCTGGTGCTGGTCCGTCTGCAGGAAGAGCGGGATCCTCTTCTGCACAAACGCTTATATAA
CGCGCTGCGCCGCGCGATCCTCGACGGTTCGCTGGCGCCGCAAAGCCGTCTGCCGCCGTCGCGGGACCTGGCGGGCGAGC
TCGGCGTATCAAGAAACACCATATTAACAACTTATGAACAATTGCTGGCGGAAGGATATGTGGTTTCCCGTCGGGGAAGC
GGAACATTCGTTGCCAAAACCGCCCCTGAGAGCTCATTGACGGCTAAAGGTCAGCAAGAAAACAGCAGTATCGCAGCACC
GACGGCGCATCTTTCACGCCGAGGCCAGCATCTGCTCGGCCAGGTCAGCGCCAGCCCGCGCCAGTGGGGAGCGTTTATAC
CCGGCGTGCCGGACGTTAACGCCTTTCCCCACCCGCTGTTCAGTAAGATCCAGGCCCGCATCAGCCGTCGGCCCAAACCG
GAGCGGCTCAGCTATAGCTGCAACGGCGGCACCCCGGAACTGCAGCAGGCGCTGGTGGATTATCTGCGCGTGTCGCGCGG
CGTCCACTGTCAGTCAGATCAAATTCTTATCACCGAGGGGATCCACCAGGCGATCGATCTGGTCACCCGCATGCTGTGTG
ATAACGGCGATCTGGCATGGGTGGAGGAGCCTTCCTACTGGGGGATCCGTCACGTGCTGGCGATGAACGACGTTCGGGCA
GAGCCCCTGACCGTCGATGCCAACGGCCTGTGCCCGCCGGAGACGGTTGACGATGCGCCGAGGCTGATCTTCGTTACGCC
TTCCCACCAGTATCCTCTGGGCGCGGTGATGAGCCTTGAGCGCCGCCAGCGCCTGCTGGCGCTCGCCCGTCAGCAGGGGA
GCTGGATCGTCGAAGATGATTATGACAGCGAGTTTCGCTTTTCCGGTCAGCCGATCCCCGCCCTGCAGGGTCTGGTCGCC
GACGCCCCGGTGGTCTATATCGGCACCTTCAGCAAGACGCTCTATCCCGGCCTGCGCCTGGGCTACGTGGTGATCCCGCG
GCCGCTGGTCAGCGACCTGAAGCACGCCCATGCCGAGCTTTACCGCGGCGGCCATTCGCTGATCCAGATGGCGCTGGCGG
AGTTTATTACCGCCGGCCACTATTCGGCCCATATCCGCCGTATGCGGCTGCTCTACAGCCGTCGCCGCGCCTTTTTAACT
GAGCTTATCCAGCGGCACTGTATGCCGTACGCCCTGTCTGACTTCAGCGATAATGCCGGGCTGCATTTGATCCTCAATTT
GCCCGCAGAGGCTGACGATGTGGCGATCGCCAGAGAGGCCAATGCGCGGCACATTCTGGTGCGGCCGCTGTCGCGCTACT
ACCTGACGGCGGCGCGCAAGAAAGGATTACTGATGGGATTCGCCAGCCAGCCCGAAGAGCAGATGGCGTCGGCGTTCAGC
GTCTTACTCGGCTGCCTGCAGACGCACTGCCCGCAGATGCTCCTGCTCCGGGAGGACGCAGAAAAACAAAACGCCCCAAC
CTGA

Upstream 100 bases:

>100_bases
GTATGTCACGTTATCGCAACAAATTAGAAACGATGTCGTTTATTTACACAGGAGTTGGCCCTATAATCGAGTACCAATTT
TGAATATCTGAGGGATCCAA

Downstream 100 bases:

>100_bases
GGCGGGGCGTTATCGGGGAGCCTGATACCAGGTATCAGGCAGGCATGGCGTATCAGGCTTCGATAGCGGCACGCAGTTTT
TTCATGGCGTTCTTTTCCAG

Product: putative GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MRSLVGDLVLVRLQEERDPLLHKRLYNALRRAILDGSLAPQSRLPPSRDLAGELGVSRNTILTTYEQLLAEGYVVSRRGS
GTFVAKTAPESSLTAKGQQENSSIAAPTAHLSRRGQHLLGQVSASPRQWGAFIPGVPDVNAFPHPLFSKIQARISRRPKP
ERLSYSCNGGTPELQQALVDYLRVSRGVHCQSDQILITEGIHQAIDLVTRMLCDNGDLAWVEEPSYWGIRHVLAMNDVRA
EPLTVDANGLCPPETVDDAPRLIFVTPSHQYPLGAVMSLERRQRLLALARQQGSWIVEDDYDSEFRFSGQPIPALQGLVA
DAPVVYIGTFSKTLYPGLRLGYVVIPRPLVSDLKHAHAELYRGGHSLIQMALAEFITAGHYSAHIRRMRLLYSRRRAFLT
ELIQRHCMPYALSDFSDNAGLHLILNLPAEADDVAIAREANARHILVRPLSRYYLTAARKKGLLMGFASQPEEQMASAFS
VLLGCLQTHCPQMLLLREDAEKQNAPT

Sequences:

>Translated_507_residues
MRSLVGDLVLVRLQEERDPLLHKRLYNALRRAILDGSLAPQSRLPPSRDLAGELGVSRNTILTTYEQLLAEGYVVSRRGS
GTFVAKTAPESSLTAKGQQENSSIAAPTAHLSRRGQHLLGQVSASPRQWGAFIPGVPDVNAFPHPLFSKIQARISRRPKP
ERLSYSCNGGTPELQQALVDYLRVSRGVHCQSDQILITEGIHQAIDLVTRMLCDNGDLAWVEEPSYWGIRHVLAMNDVRA
EPLTVDANGLCPPETVDDAPRLIFVTPSHQYPLGAVMSLERRQRLLALARQQGSWIVEDDYDSEFRFSGQPIPALQGLVA
DAPVVYIGTFSKTLYPGLRLGYVVIPRPLVSDLKHAHAELYRGGHSLIQMALAEFITAGHYSAHIRRMRLLYSRRRAFLT
ELIQRHCMPYALSDFSDNAGLHLILNLPAEADDVAIAREANARHILVRPLSRYYLTAARKKGLLMGFASQPEEQMASAFS
VLLGCLQTHCPQMLLLREDAEKQNAPT
>Mature_507_residues
MRSLVGDLVLVRLQEERDPLLHKRLYNALRRAILDGSLAPQSRLPPSRDLAGELGVSRNTILTTYEQLLAEGYVVSRRGS
GTFVAKTAPESSLTAKGQQENSSIAAPTAHLSRRGQHLLGQVSASPRQWGAFIPGVPDVNAFPHPLFSKIQARISRRPKP
ERLSYSCNGGTPELQQALVDYLRVSRGVHCQSDQILITEGIHQAIDLVTRMLCDNGDLAWVEEPSYWGIRHVLAMNDVRA
EPLTVDANGLCPPETVDDAPRLIFVTPSHQYPLGAVMSLERRQRLLALARQQGSWIVEDDYDSEFRFSGQPIPALQGLVA
DAPVVYIGTFSKTLYPGLRLGYVVIPRPLVSDLKHAHAELYRGGHSLIQMALAEFITAGHYSAHIRRMRLLYSRRRAFLT
ELIQRHCMPYALSDFSDNAGLHLILNLPAEADDVAIAREANARHILVRPLSRYYLTAARKKGLLMGFASQPEEQMASAFS
VLLGCLQTHCPQMLLLREDAEKQNAPT

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=23.5872235872236, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=23.5872235872236, Blast_Score=90, Evalue=6e-18,
Organism=Escherichia coli, GI1787710, Length=437, Percent_Identity=25.4004576659039, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790797, Length=428, Percent_Identity=27.803738317757, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=215, Percent_Identity=23.7209302325581, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56330; Mature: 56330

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLVGDLVLVRLQEERDPLLHKRLYNALRRAILDGSLAPQSRLPPSRDLAGELGVSRNT
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCH
ILTTYEQLLAEGYVVSRRGSGTFVAKTAPESSLTAKGQQENSSIAAPTAHLSRRGQHLLG
HHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHH
QVSASPRQWGAFIPGVPDVNAFPHPLFSKIQARISRRPKPERLSYSCNGGTPELQQALVD
HCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHH
YLRVSRGVHCQSDQILITEGIHQAIDLVTRMLCDNGDLAWVEEPSYWGIRHVLAMNDVRA
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCC
EPLTVDANGLCPPETVDDAPRLIFVTPSHQYPLGAVMSLERRQRLLALARQQGSWIVEDD
CCEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
YDSEFRFSGQPIPALQGLVADAPVVYIGTFSKTLYPGLRLGYVVIPRPLVSDLKHAHAEL
CCCCEEECCCCCHHHHHHHCCCCEEEEECCHHHHCCCCEECEEEECCHHHHHHHHHHHHH
YRGGHSLIQMALAEFITAGHYSAHIRRMRLLYSRRRAFLTELIQRHCMPYALSDFSDNAG
HHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LHLILNLPAEADDVAIAREANARHILVRPLSRYYLTAARKKGLLMGFASQPEEQMASAFS
EEEEEECCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
VLLGCLQTHCPQMLLLREDAEKQNAPT
HHHHHHHHCCCCEEHHHHHHHHCCCCC
>Mature Secondary Structure
MRSLVGDLVLVRLQEERDPLLHKRLYNALRRAILDGSLAPQSRLPPSRDLAGELGVSRNT
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCH
ILTTYEQLLAEGYVVSRRGSGTFVAKTAPESSLTAKGQQENSSIAAPTAHLSRRGQHLLG
HHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHH
QVSASPRQWGAFIPGVPDVNAFPHPLFSKIQARISRRPKPERLSYSCNGGTPELQQALVD
HCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHH
YLRVSRGVHCQSDQILITEGIHQAIDLVTRMLCDNGDLAWVEEPSYWGIRHVLAMNDVRA
HHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCC
EPLTVDANGLCPPETVDDAPRLIFVTPSHQYPLGAVMSLERRQRLLALARQQGSWIVEDD
CCEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
YDSEFRFSGQPIPALQGLVADAPVVYIGTFSKTLYPGLRLGYVVIPRPLVSDLKHAHAEL
CCCCEEECCCCCHHHHHHHCCCCEEEEECCHHHHCCCCEECEEEECCHHHHHHHHHHHHH
YRGGHSLIQMALAEFITAGHYSAHIRRMRLLYSRRRAFLTELIQRHCMPYALSDFSDNAG
HHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LHLILNLPAEADDVAIAREANARHILVRPLSRYYLTAARKKGLLMGFASQPEEQMASAFS
EEEEEECCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
VLLGCLQTHCPQMLLLREDAEKQNAPT
HHHHHHHHCCCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]