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The map label for this gene is gntR [H]

Identifier: 238896899

GI number: 238896899

Start: 4873875

End: 4874870

Strand: Reverse

Name: gntR [H]

Synonym: KP1_5136

Alternate gene names: 238896899

Gene position: 4874870-4873875 (Counterclockwise)

Preceding gene: 238896900

Following gene: 238896898

Centisome position: 92.88

GC content: 59.04

Gene sequence:

>996_bases
ATGAAAAAGAAAAGACCCGTACTTCAGGATGTAGCCGATCTTGTCGGCGTGACCAAAATGACGGTCAGTCGCTATTTACG
CAACCCGGAGCAGGTCTCCGAAGCGCTGCGTGGCAAGATTGCCGTTGCCCTCGATGAACTGGGTTATATTCCCAATCGCG
CCCCTGACATTCTTTCCAACGCCACCAGCCGCGCCATCGGCGTGCTGCTGCCGTCGTTAACCAACCAGGTCTTTTCGGAA
GTACTGCGCGGTATCGAAAGCGTCACCGACGCCTTCGGCTATCAAACCATGCTGGCGCACTACGGCTATAAGCCGGAAAT
GGAAGAGAAACGCCTCGAATCGATGCTCTCCTGGAACATTGATGGCCTGATCCTCACCGAACGCACCCATACGCCGCGCA
CCCTGAAGATGATCGAAGTCGCCGGCATTCCGGTGGTGGAGCTGATGGACAGCCGGTCGCCGTGTCTCGATATTGCCGTC
GGGTTTGATAACTTTGAAGCCGCCCGGCAGATGACCGCGGCGATCATCGCCCGCGGCCACCGCCATGTCGCCTATCTGGG
GGCGCGTCTTGATGAACGTACTATCATCAAACAGAAGGGGTACGAGCAGGCGATGCTTGACGCCGGGATGACGCCCTACA
GCGTGATGGTGGAACAATCCTCGTCCTATTCTTCGGGGATTGAGCTGATGCGCCAGGCGCGCCGCGAATATCCGCAGCTC
GACGGCATCTTCTGCACCAACGATGACCTCGCGGTCGGCGCGGCGTTCGAGTGCCAGCGTCTGGGGCTGAAGATCCCCGA
TGATATGGCGATCGCCGGGTTCCACGGCCATGATATCGGCCAGGTGATGGAGCCGCGGCTGGCCAGCGTCCTGACCCCGC
GCGAGCGAATGGGGCGCATCGGCGCCGAACGGCTGCTGGCGCGCATTCGTGGTGAAGCGATTACCCCTAAGATGTTAGAT
TTAGGTTTCACATTGTCACCGGGCGGATCAATTTAA

Upstream 100 bases:

>100_bases
CAGGTTAAATAAATTGCGCAGCCTTCCCTCATGTTAGGGAAGGTTGCGCTTTGTCCGTGATAAACTGAGAAAATGTTTCC
CGTTGATCACAGTCAGGACG

Downstream 100 bases:

>100_bases
ACTGACAAGTTTGAAGTAGATCACACATATTCACATCTGGCACGAATGGATATTGCTTCTCCACAGGTCCGGCATGACAA
TGTTACCGATAACAGTTACC

Product: regulator of gluconate (gnt) operon

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKKKRPVLQDVADLVGVTKMTVSRYLRNPEQVSEALRGKIAVALDELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFSE
VLRGIESVTDAFGYQTMLAHYGYKPEMEEKRLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSRSPCLDIAV
GFDNFEAARQMTAAIIARGHRHVAYLGARLDERTIIKQKGYEQAMLDAGMTPYSVMVEQSSSYSSGIELMRQARREYPQL
DGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGRIGAERLLARIRGEAITPKMLD
LGFTLSPGGSI

Sequences:

>Translated_331_residues
MKKKRPVLQDVADLVGVTKMTVSRYLRNPEQVSEALRGKIAVALDELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFSE
VLRGIESVTDAFGYQTMLAHYGYKPEMEEKRLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSRSPCLDIAV
GFDNFEAARQMTAAIIARGHRHVAYLGARLDERTIIKQKGYEQAMLDAGMTPYSVMVEQSSSYSSGIELMRQARREYPQL
DGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGRIGAERLLARIRGEAITPKMLD
LGFTLSPGGSI
>Mature_331_residues
MKKKRPVLQDVADLVGVTKMTVSRYLRNPEQVSEALRGKIAVALDELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFSE
VLRGIESVTDAFGYQTMLAHYGYKPEMEEKRLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSRSPCLDIAV
GFDNFEAARQMTAAIIARGHRHVAYLGARLDERTIIKQKGYEQAMLDAGMTPYSVMVEQSSSYSSGIELMRQARREYPQL
DGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGRIGAERLLARIRGEAITPKMLD
LGFTLSPGGSI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=94.2598187311178, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=45.4819277108434, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1790369, Length=322, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=28.3536585365854, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787906, Length=264, Percent_Identity=29.1666666666667, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=25.9375, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=25.2365930599369, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788474, Length=317, Percent_Identity=25.2365930599369, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789068, Length=320, Percent_Identity=25, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786540, Length=325, Percent_Identity=25.5384615384615, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=23.8095238095238, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=23.7082066869301, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786268, Length=336, Percent_Identity=25.5952380952381, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36597; Mature: 36597

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRPVLQDVADLVGVTKMTVSRYLRNPEQVSEALRGKIAVALDELGYIPNRAPDILSN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSRAIGVLLPSLTNQVFSEVLRGIESVTDAFGYQTMLAHYGYKPEMEEKRLESMLSWNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
DGLILTERTHTPRTLKMIEVAGIPVVELMDSRSPCLDIAVGFDNFEAARQMTAAIIARGH
CEEEEECCCCCCCCEEEHHCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
RHVAYLGARLDERTIIKQKGYEQAMLDAGMTPYSVMVEQSSSYSSGIELMRQARREYPQL
HHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCC
DGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGRI
CCEEECCCCCEECCHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHH
GAERLLARIRGEAITPKMLDLGFTLSPGGSI
HHHHHHHHHCCCCCCCHHHHCCEEECCCCCC
>Mature Secondary Structure
MKKKRPVLQDVADLVGVTKMTVSRYLRNPEQVSEALRGKIAVALDELGYIPNRAPDILSN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSRAIGVLLPSLTNQVFSEVLRGIESVTDAFGYQTMLAHYGYKPEMEEKRLESMLSWNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
DGLILTERTHTPRTLKMIEVAGIPVVELMDSRSPCLDIAVGFDNFEAARQMTAAIIARGH
CEEEEECCCCCCCCEEEHHCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
RHVAYLGARLDERTIIKQKGYEQAMLDAGMTPYSVMVEQSSSYSSGIELMRQARREYPQL
HHHHHHHHHCCHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCC
DGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGRI
CCEEECCCCCEECCHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHH
GAERLLARIRGEAITPKMLDLGFTLSPGGSI
HHHHHHHHHCCCCCCCHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]