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The map label for this gene is glpR [H]

Identifier: 238896886

GI number: 238896886

Start: 4856762

End: 4857520

Strand: Reverse

Name: glpR [H]

Synonym: KP1_5123

Alternate gene names: 238896886

Gene position: 4857520-4856762 (Counterclockwise)

Preceding gene: 238896887

Following gene: 238896884

Centisome position: 92.55

GC content: 57.58

Gene sequence:

>759_bases
ATGAAACAAACACAACGTCATGACGCCATTATCGAGCTGGTAAAAAAACAGGGTTACGTCAGCACGGAAGAGCTGGTTGA
GCAGTTCGCGGTAAGCCCGCAGACCATCCGCCGCGACCTGAACGATTTAGCCGAACAGAAAATGATCCTCCGCCATCACG
GCGGCGCGGCGCTGCCCTCCAGCTCGGTGAACACCTCCTGGCACGATCGCAAAGCGACCCAGACGGCGGAGAAAGAGCGT
ATCGCCCGGCGGGTGGCCAGCGAGATCCCGGACGGAGCGACGCTGTTTATTGATATCGGCACCACGCCGGAAGCGGTGGC
GCACGCTCTGCTCGATCACAACGATCTGCGAATTGTGACCAATAACCTTAACGTCGCCAACACGCTAATGGTGAAAGAGG
ACTTCCGCATTATTCTCGCCGGCGGCGAACTGCGTAGCCGGGACGGCGGGATTATTGGGGAAGCGACGCTGGACTTTATC
TCGCAGTTCCGCCTCGACTTCGGCATTCTCGGCATCAGCGGCGTAGACAGCGATGGCTCGCTGCTGGAGTTTGATTATCA
TGAAGTGCGCACCAAGCGGGCGATCATTGAGAATTCACGCCACGTGATGCTGGTGGTGGACCATACCAAGTTTGGCCGTA
ACGCGATGGTCAACATGGGCAGCATAAGTATGGTCGATGCGGTCTATACCGACGTGCTGCCGCCGGCCGGCGTGCTGAAG
GTGATCACTGATAACAACCTTCAGCTGGAGCTGTGCTAA

Upstream 100 bases:

>100_bases
GGCCTGGCGATGGCGTTTGTTGATACCTTACATGGGCGAAAACGCGCATAAAGACTTACCGACAGGGGTCGGGTAGGCGA
CATTTTTCCAGGGATATTTC

Downstream 100 bases:

>100_bases
ACGGCAACGGCGTCGTCAGACGCCGTATCCCATCATCTTAAGTAACTGCTGGGCATGCTGTACCGCGTCCTGCCGGTGGG
CGACGCCCAGTTTCTGATAC

Product: DNA-binding transcriptional repressor GlpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEQFAVSPQTIRRDLNDLAEQKMILRHHGGAALPSSSVNTSWHDRKATQTAEKER
IARRVASEIPDGATLFIDIGTTPEAVAHALLDHNDLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
SQFRLDFGILGISGVDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHTKFGRNAMVNMGSISMVDAVYTDVLPPAGVLK
VITDNNLQLELC

Sequences:

>Translated_252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEQFAVSPQTIRRDLNDLAEQKMILRHHGGAALPSSSVNTSWHDRKATQTAEKER
IARRVASEIPDGATLFIDIGTTPEAVAHALLDHNDLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
SQFRLDFGILGISGVDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHTKFGRNAMVNMGSISMVDAVYTDVLPPAGVLK
VITDNNLQLELC
>Mature_252_residues
MKQTQRHDAIIELVKKQGYVSTEELVEQFAVSPQTIRRDLNDLAEQKMILRHHGGAALPSSSVNTSWHDRKATQTAEKER
IARRVASEIPDGATLFIDIGTTPEAVAHALLDHNDLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
SQFRLDFGILGISGVDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHTKFGRNAMVNMGSISMVDAVYTDVLPPAGVLK
VITDNNLQLELC

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=88.0952380952381, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=44.3089430894309, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=28.6852589641434, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789519, Length=240, Percent_Identity=29.1666666666667, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789059, Length=239, Percent_Identity=30.9623430962343, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.2576419213974, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=30, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787063, Length=255, Percent_Identity=27.0588235294118, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=27.6315789473684, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=24.901185770751, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790635, Length=145, Percent_Identity=29.6551724137931, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27911; Mature: 27911

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTQRHDAIIELVKKQGYVSTEELVEQFAVSPQTIRRDLNDLAEQKMILRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNTSWHDRKATQTAEKERIARRVASEIPDGATLFIDIGTTPEAVAHALLDHNDLRIVT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFISQFRLDFGILGISGVDSDGS
CCCCEEEEEEEECCCEEEEECCCEECCCCCEEHHHHHHHHHHHHHHHEEEEECCCCCCCC
LLEFDYHEVRTKRAIIENSRHVMLVVDHTKFGRNAMVNMGSISMVDAVYTDVLPPAGVLK
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VITDNNLQLELC
EEECCCEEEEEC
>Mature Secondary Structure
MKQTQRHDAIIELVKKQGYVSTEELVEQFAVSPQTIRRDLNDLAEQKMILRHHGGAALPS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNTSWHDRKATQTAEKERIARRVASEIPDGATLFIDIGTTPEAVAHALLDHNDLRIVT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFISQFRLDFGILGISGVDSDGS
CCCCEEEEEEEECCCEEEEECCCEECCCCCEEHHHHHHHHHHHHHHHEEEEECCCCCCCC
LLEFDYHEVRTKRAIIENSRHVMLVVDHTKFGRNAMVNMGSISMVDAVYTDVLPPAGVLK
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEE
VITDNNLQLELC
EEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]