Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 238896872

GI number: 238896872

Start: 4837481

End: 4838215

Strand: Reverse

Name: ompR [H]

Synonym: KP1_5106

Alternate gene names: 238896872

Gene position: 4838215-4837481 (Counterclockwise)

Preceding gene: 238896878

Following gene: 238896871

Centisome position: 92.18

GC content: 60.27

Gene sequence:

>735_bases
TTGGGAGTACAAACAATGCAAGAGAATTATAAGATTCTGGTTGTGGATGACGACATGCGCCTGCGTGCGCTGCTCGAGCG
TTATCTGACCGAGCAGGGCTTCCAGGTTCGTAGCGTGGCGAACGCCGAACAGATGGATCGTCTGTTAACCCGTGAATCCT
TCCACCTGATGGTGCTGGATCTGATGCTGCCGGGCGAAGATGGTCTCTCTATCTGCCGTCGTCTGCGCAGCCAGAGTAAC
CCGATGCCGATCATTATGGTGACGGCGAAAGGCGAAGAGGTCGATCGGATCGTGGGTCTGGAGATCGGGGCTGACGACTA
TATTCCGAAGCCGTTTAACCCGCGCGAACTGCTGGCCCGCATCCGGGCGGTGCTGCGCCGCCAGGCGAACGAGCTGCCGG
GCGCGCCGTCGCAGGAAGAGGCGGTTATCGCCTTTGGTAAATTCAAACTGAATTTAGGCACCCGCGAGATGTTCCGTGAA
GACGAGCCGATGCCGTTGACCAGCGGCGAATTCGCGGTCCTGAAGGCGCTGGTGAGCCATCCCCGTGAGCCGCTGTCGCG
CGATAAGCTGATGAACCTCGCCCGCGGCCGCGAATACTCTGCGATGGAGCGCTCCATCGACGTACAGATCTCCCGCCTGC
GCCGCATGGTGGAAGAGGACCCGGCGCATCCGCGCTACATCCAGACCGTCTGGGGTCTGGGCTACGTCTTCGTCCCGGAC
GGTTCTAAGGCATGA

Upstream 100 bases:

>100_bases
AATATGCTTTGTAACAATTTAGCCTGGAATATATACCAGATTTAGCTGGTGAGCGCGCCGGGCTTTTTTGAGAATACGCA
CTGACTATTGCAGTGAACCT

Downstream 100 bases:

>100_bases
AACGCGTGCGCTTTTCGCCGCGCAGCTCCTTTGCTCGCACACTGCTCCTGATCGTCACCTTGCTGTTCGTCAGCCTGGTG
ACGACCTATCTGGTGGTACT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MGVQTMQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSN
PMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFRE
DEPMPLTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPD
GSKA

Sequences:

>Translated_244_residues
MGVQTMQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSN
PMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFRE
DEPMPLTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPD
GSKA
>Mature_243_residues
GVQTMQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNP
MPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFRED
EPMPLTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDG
SKA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=100, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=37.4468085106383, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=36.0515021459227, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.5545851528384, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=40.4255319148936, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.4827586206897, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=33.4745762711864, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.6491228070175, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=33.9285714285714, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=32.7510917030568, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.0813008130081, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27871; Mature: 27740

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVQTMQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLD
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCHHEEEEE
LMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLAR
EECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHHH
IRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSH
HHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHC
PREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPD
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECC
GSKA
CCCC
>Mature Secondary Structure 
GVQTMQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLD
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCHHEEEEE
LMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLAR
EECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCCHHHHHHH
IRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSH
HHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHC
PREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPD
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECC
GSKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]