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The map label for this gene is aroB [H]

Identifier: 238896857

GI number: 238896857

Start: 4821049

End: 4822143

Strand: Reverse

Name: aroB [H]

Synonym: KP1_5090

Alternate gene names: 238896857

Gene position: 4822143-4821049 (Counterclockwise)

Preceding gene: 238896858

Following gene: 238896856

Centisome position: 91.88

GC content: 58.26

Gene sequence:

>1095_bases
ATGGAGAGGCTTACTGTTACCCTCGGGGAACGTAGTTACCCGATTACCATCGCGGCTGGTTTGTTTAACGATCCAGCTTC
CTTCCTGCCACTCAAGTCGGGCGACCAGGCTATGCTGGTCACCAACGAAACGCTGGCGCCGCTTTATCTGGATACCGTCC
GCTCTGCGCTGGAGCAGTCAGGGGTCAACGTTGACAGCGTCATTCTGCCAGACGGCGAGCAATACAAAAGCCTGGCGGTG
ATGGATACCGTGTTTACTGCGCTGTTGCAAAAACCACATGGCCGCGACACCACTCTGGTGGCGCTTGGCGGGGGGGTGAT
CGGTGATTTAACCGGTTTCGCCGCGGCAAGCTATCAGCGCGGCGTGCGTTTCATCCAGGTCCCTACCACCCTGTTGTCGC
AGGTCGACTCGTCGGTCGGCGGCAAAACCGCAGTGAACCACCCTCTCGGCAAAAACATGATTGGCGCCTTCTGGCAGCCG
GTTTCCGTGGTAGTTGATCTTAACTGTCTGAAAACTCTGCCGAAGCGCGAGCTCGCTTCCGGACTGGCTGAGGTCATCAA
GTACGGGGTGATCCTGGATGGTGAATTCTTCAGCTGGCTGGAAAACAACATTGATGCGCTGCTGGCGCTGGACGATACCG
CCATGGCGTACTGCATTCGCCGCTGCTGTGAACTGAAAGCGGAGGTTGTGGCAGCCGACGAGCGTGAAACCGGGTTACGT
GCTTTACTCAATCTTGGACATACCTTCGGCCATGCTATCGAAGCGGAAATGGGCTACGGTAACTGGCTGCATGGCGAAGC
GGTGGCGGCAGGTATGGTGATGGCGGCACGCACGTCCGAACGGCTGGGGCAGTTCCGCGCGCAGGATACTCAGCGCATTA
TCGATCTGCTCAAGCGTGCAGGCTTACCGGTACGCGGCCCGCAGGAAATGAGTGCGCAGGCGTATTTGCCCCATATGATG
CGCGATAAAAAGGTACTGGCTGGCGAAATGCGGCTGGTGCTCCCGCTCGCAATAGGAAGCAGCGAGCTGCGCGGCGGAGT
GCCGCACGATGTGGTTCTTGGCGCGATTGCTGATACTCAGCAGGCGCAACAATAA

Upstream 100 bases:

>100_bases
AAAGTCGTCGCGAACCAGATTATTCATATGCTGGAAAGCAACTGATTCTGGCTTAATAAAAGTGCGTCAGAGTAATAGTC
ATTGAGGTGGATGTCGCGTT

Downstream 100 bases:

>100_bases
GAAGGTCTGGCCGCGTTCGCGCGGCGTTATCATTTCGGGTGATGTGCAATAATCGTGAGCATAAGCCTTTTAGTGGGGTG
TTAAATGGATGATTTCAAAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSALEQSGVNVDSVILPDGEQYKSLAV
MDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQP
VSVVVDLNCLKTLPKRELASGLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRAGLPVRGPQEMSAQAYLPHMM
RDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQQAQQ

Sequences:

>Translated_364_residues
MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSALEQSGVNVDSVILPDGEQYKSLAV
MDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQP
VSVVVDLNCLKTLPKRELASGLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRAGLPVRGPQEMSAQAYLPHMM
RDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQQAQQ
>Mature_364_residues
MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSALEQSGVNVDSVILPDGEQYKSLAV
MDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQP
VSVVVDLNCLKTLPKRELASGLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRAGLPVRGPQEMSAQAYLPHMM
RDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQQAQQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=88.3977900552486, Blast_Score=643, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=339, Percent_Identity=38.9380530973451, Blast_Score=200, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39186; Mature: 39186

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSALEQS
CCCEEEEECCCCCCEEEEECCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GVNVDSVILPDGEQYKSLAVMDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQPVSVVVDLNCLKTLPKRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHEEECHHHHHCCHHHHHH
GLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHCCEECCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPVRGPQEMSAQAYLPHMMRDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQ
CCCCCCCHHHCHHHHHHHHHHCCHHHHCCEEEEEEEEECCHHHCCCCCHHHHHHHHHHHH
QAQQ
HCCC
>Mature Secondary Structure
MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSALEQS
CCCEEEEECCCCCCEEEEECCCCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GVNVDSVILPDGEQYKSLAVMDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQPVSVVVDLNCLKTLPKRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHEEECHHHHHCCHHHHHH
GLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHCCEECCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPVRGPQEMSAQAYLPHMMRDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQ
CCCCCCCHHHCHHHHHHHHHHCCHHHHCCEEEEEEEEECCHHHCCCCCHHHHHHHHHHHH
QAQQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA