Click here to switch to the map view.

The map label for this gene is trkA [H]

Identifier: 238896786

GI number: 238896786

Start: 4767971

End: 4769347

Strand: Direct

Name: trkA [H]

Synonym: KP1_5008

Alternate gene names: 238896786

Gene position: 4767971-4769347 (Clockwise)

Preceding gene: 238896785

Following gene: 238896787

Centisome position: 90.84

GC content: 55.19

Gene sequence:

>1377_bases
ATGAAGATTATTATTCTGGGCGCCGGCCAGGTCGGCGGCACGCTGGCGGAAAACCTCGTCGGCGAGAACAATGATATTAC
GCTGGTTGATACCAATGGCGACCGTCTGCGCAGCCTGCAGGATAAGTTCGACCTGCGTGTCGTCCAGGGGCATGGCTCTC
ACCCTCGCGTACTGCGTGAGGCGGGGGCCGATGATGCCGATATGCTGGTAGCGGTCACTAGTTCGGACGAAACCAACATG
GTGGCCTGCCAGGTCGCTTACTCATTGTTCAATACGCCAAACCGCATAGCGCGTATTCGTGCGCCTGATTACGTTCGTGA
TGCGGAAAAGCTCTTCAACTCTGAAGCGGTACCCATCGATCACTTAATCGCTCCGGAACAACTGGTCATCGACAACATCC
ACCGTCTGATCGAATATCCCGGCGCGCTGCAGGTCGTGAACTTCGCAGAAGGAAAAGTCAGTCTCGCGGTAGTAAAAGCC
TATTATGGTGGCCCGCTGGTGGGGAATGCCTTATCCACTATGCGGGAGCATATGCCGCATATCGATACGCGCGTGGCCGC
CATTTTCCGCCACGATCGCCCCATCCGCCCGCAGGGCTCGACGATTGTCGAGGCCGGAGATGAAGTCTTCTTTATTGCCG
CCTCGCAGCATATTCGCGCGGTCATGAGCGAACTGCAGCGACTGGAAAAGCCGTATAAGCGTATTATGCTGGTCGGCGGG
GGCAATATTGGCGCGGGTCTGGCCCATAAGCTGGAAAAAGATTACAGCGTTAAGCTTATCGAACGTAATCAGCAGCGAGC
CGCTGAGCTAGCGGAAAAGCTGCAGCATACTATCGTCTTCTACGGGGATGCATCGGACCAGGAGCTGTTGGCTGAAGAGC
ATATTGACCAGGTGGACCTGTTTATTGCCGTCACTAACGACGACGAAGCCAATATTATGTCGGCTATGTTGGCCAAGCGA
ATGGGCGCGAAAAAAGTGATGGTGCTAATCCAGCGCAGAGCCTACGTGGATCTGGTCCAGGGTAGCGTCATCGATATTGC
GATTTCGCCTCAGCAGGCCACAATTTCCGCACTCCTCAGCCATGTCCGTAAAGCCGATATTGTCGGCGTCTCCTCCTTGC
GCCGCGGCGTTGCAGAAGCGATTGAGGCAGTCGCGCACGGCGATGAAAGCACCTCCCGGGTAGTCGGGCGTTCGATCGAT
GAGATCAAACTTCCACCGGGCACGATCATCGGCGCCGTCGTGCGGGGCAATGACGTGATGATCGCCAATAATAATCTACG
GATCGAGCAGGGCGACCATGTGATCATGTTTTTGACCGATAAGAAGTTTATTTCCGATGTCGAAAGGCTGTTCCAGCCAA
GTCCTTTCTTCCTGTAA

Upstream 100 bases:

>100_bases
CCGGCGAGCCCCGGGCAGCAAAATCTGCCGGGCGTGGAAGAAGGTGATGGCTTCTTTTACGCTAAGCTAATCAAACGTCG
GAACTAATGGGTCACTGCAG

Downstream 100 bases:

>100_bases
TTCCCAGGGCGCCGAACAGGCGCCTTTTTATTATCCCTTATTATTCAAAGGTTAATATTTTGCGGGAACTATCTGCTGGG
AATGGCAAATGAAAATACAT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM
VACQVAYSLFNTPNRIARIRAPDYVRDAEKLFNSEAVPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA
YYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
GNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKR
MGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRSID
EIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPFFL

Sequences:

>Translated_458_residues
MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM
VACQVAYSLFNTPNRIARIRAPDYVRDAEKLFNSEAVPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA
YYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
GNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKR
MGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRSID
EIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
>Mature_458_residues
MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM
VACQVAYSLFNTPNRIARIRAPDYVRDAEKLFNSEAVPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA
YYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
GNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKR
MGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRSID
EIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPFFL

Specific function: Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=96.5065502183406, Blast_Score=899, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50268; Mature: 50268

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCEEEEECCCCCCHHHHH
AGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRAPDYVRDAEKLFNSEAVPID
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCHH
HLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKAYYGGPLVGNALSTMREHMPH
HHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEHHCCCHHHHHHHHHHHHCCC
IDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHEEEEEEC
GNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDL
CCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCEEEE
FIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLS
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
HVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRSIDEIKLPPGTIIGAVVRGNDVM
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCEEE
IANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
EECCCEEEECCCEEEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCEEEEECCCCCCHHHHH
AGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRAPDYVRDAEKLFNSEAVPID
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCHH
HLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKAYYGGPLVGNALSTMREHMPH
HHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEHHCCCHHHHHHHHHHHHCCC
IDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHEEEEEEC
GNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDL
CCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCEEEE
FIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLS
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
HVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRSIDEIKLPPGTIIGAVVRGNDVM
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCEEE
IANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPFFL
EECCCEEEECCCEEEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]