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The map label for this gene is oadA [H]

Identifier: 238896734

GI number: 238896734

Start: 4713511

End: 4715283

Strand: Reverse

Name: oadA [H]

Synonym: KP1_4952

Alternate gene names: 238896734

Gene position: 4715283-4713511 (Counterclockwise)

Preceding gene: 238896735

Following gene: 238896733

Centisome position: 89.84

GC content: 67.34

Gene sequence:

>1773_bases
ATGACCGTTGCCATTACCGATGTCGTCCTGCGCGACGCCCACCAGTCCCTGTTCGCCACCCGTCTGCGTCTCGACGATAT
GCTGCCCGTTGCCGCTCAGCTGGACGACGTCGGCTACCGCTCGCTGGAGTGCTGGGGCGGCGCCACCTTTGACGCCTGCA
TCCGCTTTCTCGGCGAGGACCCGTGGGTCCGCCTGCGCGAGCTGAAAAAGGCGATGCCCAAGACCCCGCTGCAGATGCTG
CTCCGCGGTCAGAACCTGCTCGGCTACCGCCACTACGCCGACGACGTGGTGGAGCGCTTCGTGGAGCGCGCCGTCAAAAA
CGGCATGGACGTCTTCCGCGTCTTCGATGCCATGAACGACCCGCGCAACATGCAGGCCGCCCTGCAGGCGGTCCGCCGGC
ACGGCGCCCACGCCCAGGGTACGCTTTCGTACACCACCAGCCCGGCCCACACCCTGCAGACCTGGCTCGACCTCACCGAA
CAGCTGCTGGAGACCGGCGTTGACTCCGTCGCCATCAAGGACATGTCCGGCATTCTGACGCCGCATGCCGCCTTTGAGCT
GGTCAGCGAAATCAAGAAGCGCTACGACGTCACCCTGCACCTGCACTGCCACGCCACCACCGGCATGGCGGAGATGGCCC
TGCTGAAGGCCATTGAAGCCGGGGTCGACGGCGTCGACACCGCCATCTCCTCGATGAGCGCCACCTATGGCCACCCGGCC
ACCGAGGCGCTGGTGGCCACCCTCGCCGGCACGCAATATGACACCGGGCTGGATATCCACAGGCTGGAGGGCATCGCCGC
GTACTTTCGCGAGGTGCGCAAAAAATACCACGCCTTCGAAGGCCAGCTGAAAGGCACCGACAGCCGCATCCTGGTCGCCC
AGGTGCCGGGCGGGATGCTCACCAACCTTGAAGGCCAGCTGAAGCAGCAGAGCGCCGCCCACCGTCTGGATGAGGTGCTG
GCGGAAATCCCCCGCGTGCGCGAGGACCTCGGCTTCATCCCGCTGGTGACCCCGACCTCGCAGATTGTCGGCACCCAGGC
GGTGCTCAACGTCCTGACCGGCGAGCGCTACAAAACCATCGCGAAGGAGACCGCCGGTATCCTGAAAGGCGAGTACGGCC
GCACCCCGGCCCCGGTGAACGCCGCCCTGCAGGCGCGGGTGCTCGACGGCGCCGACCCGGTGACCTGCCGCCCGGCCGAC
CTGCTGAAGCCGGAGCTGGCGCAGCTGGAAGCGGATGTGAAACGCCAGGCACAGGAGAAGGGCATCACGCTTGCCGAAAA
CGCCATCGACGACGTGCTCACCGTGGCGCTGTTCCCGCAGCCCGGCCTGAAGTTCCTCGAAAACCGCCACAACCCGGCGG
CCTTTGAGCCGGTACCGCAGGCGGAAGCCGCGCAGCCAGTGGCAAAAGCAGAAAAACCTGCCGCCTCCGGCGTCTACACC
GTGGAGGTGGAAGGCAAAGCCTTTGTGGTCAAAGTCAGCGACGGCGGTGACGTCAGCCAGCTGACGGCGGCTGCTCCTGC
TCCTGCCTCTGCACCCGCCGCTGCCGCCCCGGCCGGCGCCGGCACCCCGGTGACCGCCCCGCTGGCGGGCACTATCTGGA
AGGTGCTGGCCAGCGAAGGCCAGACGGTGGCCGCAGGCGAGGTGCTGCTGATTCTGGAAGCCATGAAGATGGAAACCGAA
ATCCGCGCCGCGCAGGCCGGCACCGTGCGCGGTATCGCGGTGAAAGCCGGCGACGCGGTGGCGGTCGGCGACACCCTGAT
GACTCTGGCGTAA

Upstream 100 bases:

>100_bases
CGCCGTCGCGCCCGCCGACGATTTCGCCCGCCTGAAGCCGGCGATTGTCGCCGCCATTCACCACCATCGCCGTCTTCACC
CTTAATTCACGGAGGAATTC

Downstream 100 bases:

>100_bases
GGACGAGGAGCGGAAATGGAAAGTCTGAACGCCCTGATTCAGGGCATGGGGCTGATGCACCTCGGCGCCGGCCAGGCGGT
GATGCTGCTGGTCAGCCTGC

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MTVAITDVVLRDAHQSLFATRLRLDDMLPVAAQLDDVGYRSLECWGGATFDACIRFLGEDPWVRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMQAALQAVRRHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSVAIKDMSGILTPHAAFELVSEIKKRYDVTLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTQYDTGLDIHRLEGIAAYFREVRKKYHAFEGQLKGTDSRILVAQVPGGMLTNLEGQLKQQSAAHRLDEVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGRTPAPVNAALQARVLDGADPVTCRPAD
LLKPELAQLEADVKRQAQEKGITLAENAIDDVLTVALFPQPGLKFLENRHNPAAFEPVPQAEAAQPVAKAEKPAASGVYT
VEVEGKAFVVKVSDGGDVSQLTAAAPAPASAPAAAAPAGAGTPVTAPLAGTIWKVLASEGQTVAAGEVLLILEAMKMETE
IRAAQAGTVRGIAVKAGDAVAVGDTLMTLA

Sequences:

>Translated_590_residues
MTVAITDVVLRDAHQSLFATRLRLDDMLPVAAQLDDVGYRSLECWGGATFDACIRFLGEDPWVRLRELKKAMPKTPLQML
LRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMQAALQAVRRHGAHAQGTLSYTTSPAHTLQTWLDLTE
QLLETGVDSVAIKDMSGILTPHAAFELVSEIKKRYDVTLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
TEALVATLAGTQYDTGLDIHRLEGIAAYFREVRKKYHAFEGQLKGTDSRILVAQVPGGMLTNLEGQLKQQSAAHRLDEVL
AEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGRTPAPVNAALQARVLDGADPVTCRPAD
LLKPELAQLEADVKRQAQEKGITLAENAIDDVLTVALFPQPGLKFLENRHNPAAFEPVPQAEAAQPVAKAEKPAASGVYT
VEVEGKAFVVKVSDGGDVSQLTAAAPAPASAPAAAAPAGAGTPVTAPLAGTIWKVLASEGQTVAAGEVLLILEAMKMETE
IRAAQAGTVRGIAVKAGDAVAVGDTLMTLA
>Mature_589_residues
TVAITDVVLRDAHQSLFATRLRLDDMLPVAAQLDDVGYRSLECWGGATFDACIRFLGEDPWVRLRELKKAMPKTPLQMLL
RGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMNDPRNMQAALQAVRRHGAHAQGTLSYTTSPAHTLQTWLDLTEQ
LLETGVDSVAIKDMSGILTPHAAFELVSEIKKRYDVTLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPAT
EALVATLAGTQYDTGLDIHRLEGIAAYFREVRKKYHAFEGQLKGTDSRILVAQVPGGMLTNLEGQLKQQSAAHRLDEVLA
EIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGRTPAPVNAALQARVLDGADPVTCRPADL
LKPELAQLEADVKRQAQEKGITLAENAIDDVLTVALFPQPGLKFLENRHNPAAFEPVPQAEAAQPVAKAEKPAASGVYTV
EVEGKAFVVKVSDGGDVSQLTAAAPAPASAPAAAAPAGAGTPVTAPLAGTIWKVLASEGQTVAAGEVLLILEAMKMETEI
RAAQAGTVRGIAVKAGDAVAVGDTLMTLA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=626, Percent_Identity=33.2268370607029, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI106049295, Length=626, Percent_Identity=33.2268370607029, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI106049292, Length=626, Percent_Identity=33.2268370607029, Blast_Score=276, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17562816, Length=624, Percent_Identity=34.4551282051282, Blast_Score=308, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6319695, Length=633, Percent_Identity=32.8593996840442, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321376, Length=632, Percent_Identity=31.6455696202532, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652212, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652210, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652214, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI19921944, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652216, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI281363050, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652224, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652222, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652220, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24652218, Length=633, Percent_Identity=31.4375987361769, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 63031; Mature: 62900

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAITDVVLRDAHQSLFATRLRLDDMLPVAAQLDDVGYRSLECWGGATFDACIRFLGED
CEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCC
PWVRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMQAALQAVRRHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSVAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCC
PHAAFELVSEIKKRYDVTLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTQYDTGLDIHRLEGIAAYFREVRKKYHAFEGQLKGTDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
TNLEGQLKQQSAAHRLDEVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCHHHHHH
AKETAGILKGEYGRTPAPVNAALQARVLDGADPVTCRPADLLKPELAQLEADVKRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GITLAENAIDDVLTVALFPQPGLKFLENRHNPAAFEPVPQAEAAQPVAKAEKPAASGVYT
CCCHHHHHHHHHHHHEECCCCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHCCCCCCCEEE
VEVEGKAFVVKVSDGGDVSQLTAAAPAPASAPAAAAPAGAGTPVTAPLAGTIWKVLASEG
EEECCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QTVAAGEVLLILEAMKMETEIRAAQAGTVRGIAVKAGDAVAVGDTLMTLA
CEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHCC
>Mature Secondary Structure 
TVAITDVVLRDAHQSLFATRLRLDDMLPVAAQLDDVGYRSLECWGGATFDACIRFLGED
EEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCC
PWVRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVERAVKNGMDVFRVFDAMND
CHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
PRNMQAALQAVRRHGAHAQGTLSYTTSPAHTLQTWLDLTEQLLETGVDSVAIKDMSGILT
CHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCC
PHAAFELVSEIKKRYDVTLHLHCHATTGMAEMALLKAIEAGVDGVDTAISSMSATYGHPA
HHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
TEALVATLAGTQYDTGLDIHRLEGIAAYFREVRKKYHAFEGQLKGTDSRILVAQVPGGML
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
TNLEGQLKQQSAAHRLDEVLAEIPRVREDLGFIPLVTPTSQIVGTQAVLNVLTGERYKTI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCHHHHHH
AKETAGILKGEYGRTPAPVNAALQARVLDGADPVTCRPADLLKPELAQLEADVKRQAQEK
HHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHC
GITLAENAIDDVLTVALFPQPGLKFLENRHNPAAFEPVPQAEAAQPVAKAEKPAASGVYT
CCCHHHHHHHHHHHHEECCCCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHCCCCCCCEEE
VEVEGKAFVVKVSDGGDVSQLTAAAPAPASAPAAAAPAGAGTPVTAPLAGTIWKVLASEG
EEECCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QTVAAGEVLLILEAMKMETEIRAAQAGTVRGIAVKAGDAVAVGDTLMTLA
CEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]