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The map label for this gene is gatA [H]

Identifier: 238896647

GI number: 238896647

Start: 4627246

End: 4627713

Strand: Direct

Name: gatA [H]

Synonym: KP1_4852

Alternate gene names: 238896647

Gene position: 4627246-4627713 (Clockwise)

Preceding gene: 238896646

Following gene: 238896648

Centisome position: 88.16

GC content: 57.91

Gene sequence:

>468_bases
ATGAGTCAACTGTTTGTTCGTACCGGCATTCATTTCAGTTCCAGTCAGCAGGCACTGGAACACATTGGCGCAGAGATGCT
GGCGCGAGGCGTCGTACATGACAGCTATCCCGCCGCCCTGCTCGAACGCGAAGCGACTTTTCCCACCGGCATCGCCCTGG
AGAAGCATGCTGTCGCTATCCCGCACTGCGAAGCGATCCACGCGAAATCACCGGCCATTTACCTGATACGTCCGGACATG
CCGGTCTCTTTTCAGCGCGCTGACGACGACGGCGAAATCGACGTTTCGCTCATCATCGCGCTGATTGTTGAAAACCCGGC
GGCACAGCTGAAGCTGCTGCGCCGGTTATTTAGTGAGCTACAAAATCCGCACACGCTGGAGGCACTGCTCGCCGCTTCCG
ACGATCGGCTGCCGGTGCGGTTCCAGCAATTAATCCTTGAGCCCGAGCTTAGCGCCGTGGCTTCATAA

Upstream 100 bases:

>100_bases
ACGCCGAGCCGCACGCGCTGATCCTCGACAAAATCCAGGATGTCCTGCGTGCCTATCGCTACGGCTGTTCTTCTGAAACC
GCGTGAAGTTAAGAGGATAT

Downstream 100 bases:

>100_bases
GATACTGATAATAAAAGGGGTACCCTATGAAACGTAAAGTTATCGTCGCCTGCGGCGGTGCCGTCGCCACCTCCACGATG
GCGGCAGAAGAGATTAAAGA

Product: PTS system galactitol-specific transporter subunit IIA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Gat; PTS system galactitol-specific EIIA component [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSQLFVRTGIHFSSSQQALEHIGAEMLARGVVHDSYPAALLEREATFPTGIALEKHAVAIPHCEAIHAKSPAIYLIRPDM
PVSFQRADDDGEIDVSLIIALIVENPAAQLKLLRRLFSELQNPHTLEALLAASDDRLPVRFQQLILEPELSAVAS

Sequences:

>Translated_155_residues
MSQLFVRTGIHFSSSQQALEHIGAEMLARGVVHDSYPAALLEREATFPTGIALEKHAVAIPHCEAIHAKSPAIYLIRPDM
PVSFQRADDDGEIDVSLIIALIVENPAAQLKLLRRLFSELQNPHTLEALLAASDDRLPVRFQQLILEPELSAVAS
>Mature_154_residues
SQLFVRTGIHFSSSQQALEHIGAEMLARGVVHDSYPAALLEREATFPTGIALEKHAVAIPHCEAIHAKSPAIYLIRPDMP
VSFQRADDDGEIDVSLIIALIVENPAAQLKLLRRLFSELQNPHTLEALLAASDDRLPVRFQQLILEPELSAVAS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788410, Length=149, Percent_Identity=59.0604026845638, Blast_Score=186, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 17023; Mature: 16892

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLFVRTGIHFSSSQQALEHIGAEMLARGVVHDSYPAALLEREATFPTGIALEKHAVAI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEECCCEEEC
PHCEAIHAKSPAIYLIRPDMPVSFQRADDDGEIDVSLIIALIVENPAAQLKLLRRLFSEL
CCCHHHCCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QNPHTLEALLAASDDRLPVRFQQLILEPELSAVAS
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
SQLFVRTGIHFSSSQQALEHIGAEMLARGVVHDSYPAALLEREATFPTGIALEKHAVAI
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEECCCEEEC
PHCEAIHAKSPAIYLIRPDMPVSFQRADDDGEIDVSLIIALIVENPAAQLKLLRRLFSEL
CCCHHHCCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QNPHTLEALLAASDDRLPVRFQQLILEPELSAVAS
CCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]