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The map label for this gene is fadH [H]

Identifier: 238896607

GI number: 238896607

Start: 4588701

End: 4590722

Strand: Direct

Name: fadH [H]

Synonym: KP1_4808

Alternate gene names: 238896607

Gene position: 4588701-4590722 (Clockwise)

Preceding gene: 238896606

Following gene: 238896610

Centisome position: 87.43

GC content: 62.86

Gene sequence:

>2022_bases
ATGAGCCGCTATCCGTCGCTTTTCGCCCCGCTTGAGCTGGGCTTCACAACGCTCAAAAACCGCGTGTTGATGGGCTCGAT
GCACACCGGGCTGGAAGAGCTGCCGGACGGCGCGCAGCGGCTGGCGGCCTTTTACGCCGAACGCGCCCGTCACGGCGTGG
CGCTGATCGTCACCGGCGGCATCGCTCCGGCGCCCTCTGGCGTCACCATGGCCGGCGGCGCGGTACTCAACGACGCCAGC
CATCTGGCGCATCATCGCCATATTACCGATGCGGTACATCAGGAAGGCGGCAAAATCGCTCTGCAGATCCTGCACACCGG
CCGTTACAGCTACCAGCCCGCGCTGGTGGCCCCCTCGGCGCTACAGGCGCCGATCAACCGTTTTACCCCCCATGAACTGA
GCCACGATGAGATCCTGACGCTGATCGATGATTTTGCCCACTGCGCCCAACTGGCGCGCGAAGCGGGATATGACGGCGTC
GAAGTGATGGGCTCTGAGGGCTATCTGATTAACGAATTTCTCGCCGCGCGCACCAACCAGCGCGACGACCAATGGGGCGG
CGATTATGCCAGGCGCATGCGTTTCGCCGTAGAGGTGGTTAAGGCGGTACGCCAGCGCGCCGGCCACGATTTCATTATCA
TCTACCGCCTATCGATGCTCGATCTGGTCAACGACGGCAGCACGCTGGCGGAAGTCACCGAACTGGCCAAAGCGATTGAA
GCGGCGGGAGCGACCATCATCAACACCGGGATTGGCTGGCACGAAGCGCGCATTCCGACCATCGCCACGCCGGTACCGCG
CGGAGCTTTCAGCTGGGTCACCCGCAAGCTGAAGGGCGCGGTGTCGATCCCGTTGATCACCACCAACCGCATTAACGATC
CGCAGGTCGCGGAGGATATTCTCGCCCGCGGCGATGCCGATATGGTATCGATGGCCCGCCCGTTCCTTGCCGACGCCGAA
TTTATATCAAAAGCGCAGGACGATCGCGCCGATCAGATCAACACCTGCATCGGCTGCAATCAGGCGTGTCTCGATCGGAT
CTTCGTCGGCAAAGTCACCTCCTGTCTGGTCAACCCGCGCGCGTGTCATGAAACCCTGATGCCGGTCCTGCCTGCCAACG
CGCCTAAACGGCTGGCGGTGGTCGGCGCCGGGCCTGCCGGTCTGGCCTTCGCCGTAAACGCTGCCGCCCGTGGTCATCAC
GTCACGTTGTTTGATGCGCTCCCGGAGATCGGCGGTCAGTTTAATATCGCCAAACAGATCCCCGGCAAAGAGGAGTTTCA
CGAGACGCTGCGTTACTACCGCACCATGCTCGATCTGCATGGTGTCGATCTACGCCTGAACACCCGCGTCACGACAGACG
ATCTGCTGGCGTTCGATGAGACGATCCTCGCCACCGGTATCGCCCCGCGCCTGCCGGCGATCGACGGGATCGAACATCCC
AAAGTGCTGAGCTACCTTGATGTCTTGCGCGATAAAGCGCCGGTTGGCGCGAAGGTGGCGATTATCGGCTGCGGCGGCAT
CGGCTTCGACACCGCGATGTTTTTAAGCCAGTCGGGCGCGGCCACCAGCCAGGATATCGGCGAGTTCTGCCGCGAATGGG
GTATCGATACCAGCCTGCAAACGGCGGGAGGGCTGAGTGCTGAAGGCCCGCAGCTGAGTAAAAGCCCGCGACAGATTGTG
ATGCTGCAGCGCAAAGCCAGCAAACCGGGCGAAGGGCTCGGCAAAACCACCGGCTGGATCCACCGCGCGACGCTGCTGGC
GCGCGGGGTGAAAATGATCCCGGCGGTCAGCTATGAAAAGATCGATGATGAAGGGTTACATGTTACTATCGGCGGCGAGC
GCCAGTTGCTGGCGGTCGATCAGGTGGTGATCTGCGCCGGTCAGGAGCCGCGCCGCGAGCTGGCGGATCCGCTGCGCGCG
GCGGGGAAAACGGTGCATCTCATCGGCGGTTGCGACGTGGCGGCGGAGCTGGATGCGCGCCGGGCGATTGCCCAGGGCAC
TAAACTGGCGCTGGCGATTTAG

Upstream 100 bases:

>100_bases
CCATCACAATCACCGCACTCCCCTTTTCCCTTTTTCTCCACGATGGCTAAATTAGTAACTCATCCGACCACATAACAATA
ATTTTACATTGGAAGCCACT

Downstream 100 bases:

>100_bases
CCCTGTCCCGGGGGCGGCGCGATGCGCCTTCACCGGGCTACCACGATAATCCCGCACGCTAGCCCGGCTAAGGCGACAGC
CGCGAGCCGGGGGAAACCGC

Product: 2,4-dieonyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGGIAPAPSGVTMAGGAVLNDAS
HLAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSALQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGV
EVMGSEGYLINEFLAARTNQRDDQWGGDYARRMRFAVEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAKAIE
AAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDILARGDADMVSMARPFLADAE
FISKAQDDRADQINTCIGCNQACLDRIFVGKVTSCLVNPRACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHH
VTLFDALPEIGGQFNIAKQIPGKEEFHETLRYYRTMLDLHGVDLRLNTRVTTDDLLAFDETILATGIAPRLPAIDGIEHP
KVLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMFLSQSGAATSQDIGEFCREWGIDTSLQTAGGLSAEGPQLSKSPRQIV
MLQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEKIDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRA
AGKTVHLIGGCDVAAELDARRAIAQGTKLALAI

Sequences:

>Translated_673_residues
MSRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGGIAPAPSGVTMAGGAVLNDAS
HLAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSALQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGV
EVMGSEGYLINEFLAARTNQRDDQWGGDYARRMRFAVEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAKAIE
AAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDILARGDADMVSMARPFLADAE
FISKAQDDRADQINTCIGCNQACLDRIFVGKVTSCLVNPRACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHH
VTLFDALPEIGGQFNIAKQIPGKEEFHETLRYYRTMLDLHGVDLRLNTRVTTDDLLAFDETILATGIAPRLPAIDGIEHP
KVLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMFLSQSGAATSQDIGEFCREWGIDTSLQTAGGLSAEGPQLSKSPRQIV
MLQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEKIDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRA
AGKTVHLIGGCDVAAELDARRAIAQGTKLALAI
>Mature_672_residues
SRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGGIAPAPSGVTMAGGAVLNDASH
LAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSALQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGVE
VMGSEGYLINEFLAARTNQRDDQWGGDYARRMRFAVEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAKAIEA
AGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDILARGDADMVSMARPFLADAEF
ISKAQDDRADQINTCIGCNQACLDRIFVGKVTSCLVNPRACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHHV
TLFDALPEIGGQFNIAKQIPGKEEFHETLRYYRTMLDLHGVDLRLNTRVTTDDLLAFDETILATGIAPRLPAIDGIEHPK
VLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMFLSQSGAATSQDIGEFCREWGIDTSLQTAGGLSAEGPQLSKSPRQIVM
LQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEKIDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRAA
GKTVHLIGGCDVAAELDARRAIAQGTKLALAI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=670, Percent_Identity=83.2835820895522, Blast_Score=1154, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=352, Percent_Identity=29.5454545454545, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17564188, Length=228, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=220, Percent_Identity=26.3636363636364, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=226, Percent_Identity=28.3185840707965, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=223, Percent_Identity=28.2511210762332, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=234, Percent_Identity=24.7863247863248, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=213, Percent_Identity=25.8215962441315, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=230, Percent_Identity=25.2173913043478, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=254, Percent_Identity=26.7716535433071, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72236; Mature: 72105

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGG
CCCCCCCCCHHHHHHHHHHHHHEECHHHHCHHHCCCHHHHHHHHHHHHHCCCEEEEEECC
IAPAPSGVTMAGGAVLNDASHLAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSA
CCCCCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCHH
LQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGVEVMGSEGYLINEFLAARTNQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
RDDQWGGDYARRMRFAVEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAKAIE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHH
AAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDI
HCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
LARGDADMVSMARPFLADAEFISKAQDDRADQINTCIGCNQACLDRIFVGKVTSCLVNPR
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCH
ACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHHVTLFDALPEIGGQFNIAKQI
HHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEHHHHHHHHCCCEEEHHCC
PGKEEFHETLRYYRTMLDLHGVDLRLNTRVTTDDLLAFDETILATGIAPRLPAIDGIEHP
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KVLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMFLSQSGAATSQDIGEFCREWGIDTSLQ
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCH
TAGGLSAEGPQLSKSPRQIVMLQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEK
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCHHC
IDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRAAGKTVHLIGGCDVAAELDAR
CCCCCEEEEECCCCEEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
RAIAQGTKLALAI
HHHHCCCEEEEEC
>Mature Secondary Structure 
SRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGG
CCCCCCCCHHHHHHHHHHHHHEECHHHHCHHHCCCHHHHHHHHHHHHHCCCEEEEEECC
IAPAPSGVTMAGGAVLNDASHLAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSA
CCCCCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCHH
LQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGVEVMGSEGYLINEFLAARTNQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
RDDQWGGDYARRMRFAVEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAKAIE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHHH
AAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDI
HCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
LARGDADMVSMARPFLADAEFISKAQDDRADQINTCIGCNQACLDRIFVGKVTSCLVNPR
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCH
ACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHHVTLFDALPEIGGQFNIAKQI
HHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEHHHHHHHHCCCEEEHHCC
PGKEEFHETLRYYRTMLDLHGVDLRLNTRVTTDDLLAFDETILATGIAPRLPAIDGIEHP
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
KVLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMFLSQSGAATSQDIGEFCREWGIDTSLQ
HHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCH
TAGGLSAEGPQLSKSPRQIVMLQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEK
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCHHC
IDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRAAGKTVHLIGGCDVAAELDAR
CCCCCEEEEECCCCEEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
RAIAQGTKLALAI
HHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]