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The map label for this gene is ydeV [H]

Identifier: 238896606

GI number: 238896606

Start: 4586919

End: 4588517

Strand: Direct

Name: ydeV [H]

Synonym: KP1_4807

Alternate gene names: 238896606

Gene position: 4586919-4588517 (Clockwise)

Preceding gene: 238896605

Following gene: 238896607

Centisome position: 87.39

GC content: 64.29

Gene sequence:

>1599_bases
ATGAGTTACCTGTTAGCGTTAGATGCCGGGACCGGCAGCATTCGGGCGGTTATTTTCGATCTTAATGGCCGCCAGCTGGC
GGTAGGCCAGGCCGAATGGAAACACCTGAGCGTTGATAACGTCCCCGGCTCGATGGAGTTCGACCTTACCACCAACTGGC
AGCTGGCCTGCCAGTGCATTCGCCAGGCGCTCGACGCCGCCCGGCTCTCTGCCGCCGATATTCAGTCCGTCGCCTGCTGT
TCGATGCGCGAAGGCATCGTTCTCTATGACCGCAACGGCGAGGCCATCTGGGCCTGCGCCAACGTCGATGCCCGCGCCAG
CCGCGAAGTGGCGGAGCTTAAGGAGATCCACGACTATCGCTTCGAATCCGAGGTATACGAGGTCTCGGGACAAACCCTGG
CGCTCAGCGCCATGCCGCGCCTGCTGTGGCTGGCGCACCACCGCCCCGATATCTACCGCAAAGCGGCAACCATCACCATG
ATCAGCGACTGGCTGGCGGCGAAGCTTTCCGGCGAGCTGGCGGTCGACCCGTCAAACGCCGGCACCACCGGCATGCTCGA
TCTGTTCAGCCGCGACTGGCGTCCGGCGCTGCTGGATATGGCCGGGCTGCGCGCCGATATGCTGTCGCCGGTCAAAGAGA
CCGGTACCCTGCTGGGCGCCGTCACCGAAGCGGCGGCGCAGCAGAGCGGCCTGCGCGCCGGGACGCCGGTGGTGATGGGC
GGCGGCGACGTCCAGCTCGGCTGCCTGGGCCTTGGGGTGGTGCGCGCCGGGCAAACCGCGGTACTCGGCGGCACTTTCTG
GCAGCAGGTGGTCAACCTGCCGCAGGTGCGTACCGATCCGCAGATGAATATTCGCGTTAATCCTCACGTGATTCCCGGCA
TGGCGCAGGCGGAATCGATCAGCTTCTTTACCGGCCTGACCATGCGCTGGTTTCGCGACGCCTTCTGCGCTGAAGAAAAA
CTGATTGCCGAGCGGCTCGGCGTCGATGCCTATTCGCTGCTGGAGGAGATGGCCAGCCGCGTGCCCGCCGGTTCCCACGG
CGTGATGCCTATTTTTTCCGACGCCATGCACTTTAAGCAGTGGTACCACGCCGCGCCGTCGTTTATTAACCTCTCCATCG
ATCCGGAGAAGTGCAATAAAGCGACCCTGTTCCGCGCGCTGGAGGAGAACGCGGCGATTGTCTCCGCCTGCAACCTGGCC
CAGATTTCGCAGTTCTCCGGGGTAACATTCGAGAGCATGGTGTTTGCCGGCGGCGGCTCTAAAGGCGCGCTGTGGAGCCA
GATCCTCAGCGACGTCACCGGCCTGCCGGTGCGGGTGCCGGTGGTCCGCGAAGCCACCGCGCTGGGCTGCGCCATCGCCG
CCGGAACCGGCGCCGGGCTGTATGACGATATGGCCAGCACCGGAGAGCGGTTAGTGAGCTGGCACCGCGAGTTCACCCCA
AATCCGCAGCATCGCGAGCTGTATCAGGAGATGATGAGCAAGTGGCAGACGGTGTACGCCGATCAGCTTGGCCTTGTCGA
TAGCGGACTGACAACGTCGATGTGGCAGGCGCCGGGTCTGGAACGCCGCCAGCGCGTTGCGTCTTCCCCCTCACCCTAA

Upstream 100 bases:

>100_bases
CGCATTAATGGCCTGGTAACGGAAGAGACAACAGCACGCGCGGTGCTTACCCTGGCCTCCTGACGGCCTGGCGCCGCGCG
ACAACAGCGAGGCGCATGTC

Downstream 100 bases:

>100_bases
CTACCGGTGCCGCTCCGCCTTTCCCCCCTCTCCCTTTGGGAGAGGGCCGGGGTGTGGGGAAACGCTTCGCCGTTCTTTGA
ATCCCATCACAATCACCGCA

Product: autoinducer-2 (AI-2) kinase

Products: NA

Alternate protein names: AI-2 kinase [H]

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCIRQALDAARLSAADIQSVACC
SMREGIVLYDRNGEAIWACANVDARASREVAELKEIHDYRFESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITM
ISDWLAAKLSGELAVDPSNAGTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTEAAAQQSGLRAGTPVVMG
GGDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESISFFTGLTMRWFRDAFCAEEK
LIAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLA
QISQFSGVTFESMVFAGGGSKGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYDDMASTGERLVSWHREFTP
NPQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVASSPSP

Sequences:

>Translated_532_residues
MSYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCIRQALDAARLSAADIQSVACC
SMREGIVLYDRNGEAIWACANVDARASREVAELKEIHDYRFESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITM
ISDWLAAKLSGELAVDPSNAGTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTEAAAQQSGLRAGTPVVMG
GGDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESISFFTGLTMRWFRDAFCAEEK
LIAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLA
QISQFSGVTFESMVFAGGGSKGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYDDMASTGERLVSWHREFTP
NPQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVASSPSP
>Mature_531_residues
SYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCIRQALDAARLSAADIQSVACCS
MREGIVLYDRNGEAIWACANVDARASREVAELKEIHDYRFESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITMI
SDWLAAKLSGELAVDPSNAGTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTEAAAQQSGLRAGTPVVMGG
GDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESISFFTGLTMRWFRDAFCAEEKL
IAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLAQ
ISQFSGVTFESMVFAGGGSKGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYDDMASTGERLVSWHREFTPN
PQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVASSPSP

Specific function: Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787789, Length=518, Percent_Identity=77.7992277992278, Blast_Score=846, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=515, Percent_Identity=24.0776699029126, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789168, Length=505, Percent_Identity=22.1782178217822, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790361, Length=504, Percent_Identity=25.7936507936508, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789138, Length=496, Percent_Identity=24.3951612903226, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789987, Length=440, Percent_Identity=24.0909090909091, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535599, Length=277, Percent_Identity=26.3537906137184, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: NA

Molecular weight: Translated: 57692; Mature: 57561

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCI
CCEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCEEEEECCCHHHHHHHH
RQALDAARLSAADIQSVACCSMREGIVLYDRNGEAIWACANVDARASREVAELKEIHDYR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHH
FESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITMISDWLAAKLSGELAVDPSNA
HHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
GTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTEAAAQQSGLRAGTPVVMG
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
GGDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESI
CCCEEEEEEEEHHHCCCCEEEECHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHH
SFFTGLTMRWFRDAFCAEEKLIAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
WYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLAQISQFSGVTFESMVFAGGGS
HHHCCCCEEEEEECHHHCCHHHHHHHHHHCCHHEECCCHHHHHHHCCCCHHHEEEECCCC
KGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYDDMASTGERLVSWHREFTP
CCHHHHHHHHHHCCCCEEEEHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
NPQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVASSPSP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCI
CEEEEEECCCCCEEEEEEECCCCEEEECCCCCCEEECCCCCCCEEEEECCCHHHHHHHH
RQALDAARLSAADIQSVACCSMREGIVLYDRNGEAIWACANVDARASREVAELKEIHDYR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHH
FESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITMISDWLAAKLSGELAVDPSNA
HHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
GTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTEAAAQQSGLRAGTPVVMG
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
GGDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESI
CCCEEEEEEEEHHHCCCCEEEECHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHH
SFFTGLTMRWFRDAFCAEEKLIAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
WYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLAQISQFSGVTFESMVFAGGGS
HHHCCCCEEEEEECHHHCCHHHHHHHHHHCCHHEECCCHHHHHHHCCCCHHHEEEECCCC
KGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYDDMASTGERLVSWHREFTP
CCHHHHHHHHHHCCCCEEEEHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
NPQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVASSPSP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA