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The map label for this gene is ygjG [H]

Identifier: 238896597

GI number: 238896597

Start: 4578526

End: 4579932

Strand: Direct

Name: ygjG [H]

Synonym: KP1_4798

Alternate gene names: 238896597

Gene position: 4578526-4579932 (Clockwise)

Preceding gene: 238896596

Following gene: 238896605

Centisome position: 87.23

GC content: 59.56

Gene sequence:

>1407_bases
GTGATACGTCCGCCCCAGGAGCACATTTTGAACAGGTTACCTTCCAGCGCATCGGCTCTGGCCTGCAGCGCACACGCACT
GAATCTCATTGAAAAGCGCACGCTTGATCATGAGGAAATGAAAGCACTTAACCAGGAGGTCAGGGAATACTTTAAAGAGC
ATGTGAATCCGGGGTTTTTAGAGTATCGAAAATCGGTCACAGCCGGCGGGGATTACGGAGCCGTAGAGTGGCAAGCGGGA
GGGTTAAATACGCTTGTCGACACCCAGGGACAGGAGTTTATCGACTGCCTTGGTGGGTTTGGTATCTTCAATGTAGGGCA
CCGTAATCCAGTTGTGGTATCCGCCGTCGAGAATCAACTCGCGAAACAACCGCTTCACAGTCAGGAGCTGCTGGACCCGC
TACGCGCGATGCTGGCGAAAACCCTGGCAGCCTTAACGCCCGGGAAACTAAAGTACAGTTTCTTCTGCAACAGCGGTACC
GAATCGGTAGAGGCGGCCATCAAGCTGGCGAAAGCCTATCAGTCGCCGCGCGGTAAATTTACCTTCATCGCCACCAGCGG
CGCCTTCCACGGTAAATCGCTGGGCGCGCTGTCGGCCACCGCCAAGTCGACCTTCCGCAAACCCTTTATGCCGCTGCTGC
CGGGCTTCCGCCACGTGCCGTTCGGCGATATCACCGCCATGCGCACCATGCTGAGCGAGTGCAAGAAAACCGGCGACGAC
GTCGCGGCGGTGATCCTCGAGCCGATTCAGGGCGAAGGGGGCGTGATCCTCCCGCCAACGGGGTATTTGCCGGCGGTGCG
TAAACTGTGCGACGAGTTTGGCGCATTGCTGATCCTCGACGAAGTGCAGACCGGCATGGGCCGCACCGGCAAGATGTTCG
CCTGTGAGCATGAGAACGTCCAGCCGGACATTCTGTGTCTGGCGAAAGCGCTCGGCGGCGGTGTGATGCCGATCGGCGCG
ACGGTGGCGACGGAAGAGGTCTTCTCGGTGCTCTTCGATAACCCGTTCCTGCACACCACCACCTTCGGCGGCAACCCGTT
GGCCTGTGCGGCGGCGCTGGCGACGATCAACGTGCTGCTGACGCAAAACCTGCCGGCGCAGGCGGCGCAGAAAGGCGATA
TGCTGCTGGACGGTTTCCGCCTGCTGGCGCAGGAGTATCCGGACCTGGTGAATGAAGTGCGCGGGAAAGGCATGCTGATG
GCTATCGAGTTTGTTGATAACGAGATTGGCTACGACTTTGCCAGCGAGATGTTCAGACAGCGGGTGCTGGTCGCCGGGAC
GTTAAACAACGCCAAGACGATCCGCATTGAACCGCCGCTGACGCTCACCCTTGAGCAGTGCGAACAGGTGCTGAAGGCGG
CGCGCAAGGCGCTGGCGGCCCTGCGCGTTTCGGTCGAAGAAGCGTAA

Upstream 100 bases:

>100_bases
ATTAAATTTTACACAATTCGTCTTTTGCTTTGCATTTATCCCGATTTTCACCGCTTCTGCCGAACTGGCGTAATCCCTGC
AATACTTAATCCAGTATCGT

Downstream 100 bases:

>100_bases
TAAAGTGTCCTTCACCCTCTCCCTCTGAGAGGGTGAAGGATAACCCTCACACCTGCGGTAACAGGCCGATAAAGCTGCGC
TTCTGCCGCGGCTGCGACAT

Product: putrescine--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MIRPPQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAAIKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDITAMRTMLSECKKTGDD
VAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLTQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLM
AIEFVDNEIGYDFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA

Sequences:

>Translated_468_residues
MIRPPQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAAIKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDITAMRTMLSECKKTGDD
VAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLTQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLM
AIEFVDNEIGYDFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA
>Mature_468_residues
MIRPPQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAG
GLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGT
ESVEAAIKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDITAMRTMLSECKKTGDD
VAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
TVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLTQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLM
AIEFVDNEIGYDFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=33.0749354005168, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI284507298, Length=312, Percent_Identity=35.5769230769231, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI37574042, Length=405, Percent_Identity=27.6543209876543, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI13994255, Length=458, Percent_Identity=29.4759825327511, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226442705, Length=405, Percent_Identity=27.4074074074074, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=27.7922077922078, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI24119277, Length=397, Percent_Identity=27.9596977329975, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI188536080, Length=434, Percent_Identity=23.5023041474654, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38679950, Length=434, Percent_Identity=23.5023041474654, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI38679946, Length=434, Percent_Identity=23.5023041474654, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI145693181, Length=459, Percent_Identity=94.5533769063181, Blast_Score=867, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=369, Percent_Identity=35.5013550135501, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789759, Length=325, Percent_Identity=37.8461538461538, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=35.7682619647355, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786991, Length=390, Percent_Identity=30.5128205128205, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=30.5389221556886, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=370, Percent_Identity=32.972972972973, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI25144274, Length=261, Percent_Identity=37.9310344827586, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=28.2352941176471, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=418, Percent_Identity=26.555023923445, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=22.5287356321839, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=34.3669250645995, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=393, Percent_Identity=31.2977099236641, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324386, Length=456, Percent_Identity=26.3157894736842, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=432, Percent_Identity=22.9166666666667, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=33.5064935064935, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=32.3529411764706, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI28574759, Length=443, Percent_Identity=29.7968397291196, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI161085790, Length=424, Percent_Identity=30.6603773584906, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281366494, Length=310, Percent_Identity=26.4516129032258, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667139, Length=310, Percent_Identity=26.4516129032258, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667143, Length=310, Percent_Identity=26.4516129032258, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 50589; Mature: 50589

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPPQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFL
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
EYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQL
HHHHHHCCCCCCCCEEEECCCCCHHHCCCCHHHHHHHCCCCEEECCCCCCEEEHHHHHHH
AKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAAIKLAKAYQSPRGKF
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCE
TFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDITAMRTMLSECKKTGDD
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENV
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCEEEECCCCC
QPDILCLAKALGGGVMPIGATVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
TQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLMAIEFVDNEIGYDFASEMFRQ
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
RVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA
HHHEEEECCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRPPQEHILNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFL
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHH
EYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQL
HHHHHHCCCCCCCCEEEECCCCCHHHCCCCHHHHHHHCCCCEEECCCCCCEEEHHHHHHH
AKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAAIKLAKAYQSPRGKF
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCE
TFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDITAMRTMLSECKKTGDD
EEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENV
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCEEEECCCCC
QPDILCLAKALGGGVMPIGATVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
TQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLMAIEFVDNEIGYDFASEMFRQ
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
RVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA
HHHEEEECCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA