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The map label for this gene is hexR [C]

Identifier: 238896441

GI number: 238896441

Start: 4419120

End: 4419848

Strand: Direct

Name: hexR [C]

Synonym: KP1_4618

Alternate gene names: 238896441

Gene position: 4419120-4419848 (Clockwise)

Preceding gene: 238896438

Following gene: 238896442

Centisome position: 84.2

GC content: 51.85

Gene sequence:

>729_bases
ATGTTCTCCCACGCCGCTGTCGCCAGTCTCAATAATCTTGAGATGATGGTCTACCACTACGTCATTAAAAATCGTGACAA
AGTGATGTACATGACCATCCGCGAACTGGCCGAGGCCGCCGGGGTCTCCACGACCACCGTGTTACGCTTCTGCCGCAAAC
TGCAGTGCGAGGGCTACTCTGAATTTCGCGTGCGCTTTAAATTATATCTCGAGCAGAATGAGCCTCAACAGGCAAATATC
GGCGCCAGCGAAATAATGAGCTTTTTTAAAAGCGTCAATAATGACGAGTTCGATGAATTACTCGAGCAGGCCGTCGATAT
TATTCTCGCCTCCGAACGTATTATTTTTGTCGGCGCCGGCACCTCCGGCGCGCTGGCGAAATATGGCGCACGCTTCTTCT
CCAACGTCGGTAAATTCAGCAACCATATTGACGACCCCTATTTTCCGGTAACCAACGATATGGCCCGCAACGCGCTGGCG
ATCGTGCTTTCCGTCTCTGGCGAGACGGAAGAGATCCTGCGCTTTGCCAGCCAGTTCAGCCTGCATCATTGCAAGGTGAT
GTCGATTACCAGCCATGAGCATTCGCGGCTGGCCAAACTGGCTGATTTCAATCTCTCCTGGCACGTGCCGCAGACGCGCA
TCGGCGGCGTCTACGATATTACAACGCAAATTCCAGTGATCTATATTCTCGAATCCCTCGGACGTAAATTAGCGCGCAAA
ATCAGCTAA

Upstream 100 bases:

>100_bases
GAGGATGTCGTCCTGAAAACGCTGAAAAAAGGTAATGTCATTGGCCTGCATGATATAATTCCGTCCTGGTCATTATGAAT
TGTGAGTTCGCCCTGTGAGT

Downstream 100 bases:

>100_bases
AAATAACAGCCTGTTTTTTTGATGTAACATATTACCTTTGGCGGAATTTGTTATATCGTGACATTCACTTTCACTTTGCT
AGACTCGAGAACAATAGTTA

Product: putative regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MFSHAAVASLNNLEMMVYHYVIKNRDKVMYMTIRELAEAAGVSTTTVLRFCRKLQCEGYSEFRVRFKLYLEQNEPQQANI
GASEIMSFFKSVNNDEFDELLEQAVDIILASERIIFVGAGTSGALAKYGARFFSNVGKFSNHIDDPYFPVTNDMARNALA
IVLSVSGETEEILRFASQFSLHHCKVMSITSHEHSRLAKLADFNLSWHVPQTRIGGVYDITTQIPVIYILESLGRKLARK
IS

Sequences:

>Translated_242_residues
MFSHAAVASLNNLEMMVYHYVIKNRDKVMYMTIRELAEAAGVSTTTVLRFCRKLQCEGYSEFRVRFKLYLEQNEPQQANI
GASEIMSFFKSVNNDEFDELLEQAVDIILASERIIFVGAGTSGALAKYGARFFSNVGKFSNHIDDPYFPVTNDMARNALA
IVLSVSGETEEILRFASQFSLHHCKVMSITSHEHSRLAKLADFNLSWHVPQTRIGGVYDITTQIPVIYILESLGRKLARK
IS
>Mature_242_residues
MFSHAAVASLNNLEMMVYHYVIKNRDKVMYMTIRELAEAAGVSTTTVLRFCRKLQCEGYSEFRVRFKLYLEQNEPQQANI
GASEIMSFFKSVNNDEFDELLEQAVDIILASERIIFVGAGTSGALAKYGARFFSNVGKFSNHIDDPYFPVTNDMARNALA
IVLSVSGETEEILRFASQFSLHHCKVMSITSHEHSRLAKLADFNLSWHVPQTRIGGVYDITTQIPVIYILESLGRKLARK
IS

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 27360; Mature: 27360

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSHAAVASLNNLEMMVYHYVIKNRDKVMYMTIRELAEAAGVSTTTVLRFCRKLQCEGYS
CCCCHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
EFRVRFKLYLEQNEPQQANIGASEIMSFFKSVNNDEFDELLEQAVDIILASERIIFVGAG
HHEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECC
TSGALAKYGARFFSNVGKFSNHIDDPYFPVTNDMARNALAIVLSVSGETEEILRFASQFS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEEECCCCHHHHHHHHHHHC
LHHCKVMSITSHEHSRLAKLADFNLSWHVPQTRIGGVYDITTQIPVIYILESLGRKLARK
HHHEEEEEECCCHHHHHHHHHCCCCEECCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
IS
CC
>Mature Secondary Structure
MFSHAAVASLNNLEMMVYHYVIKNRDKVMYMTIRELAEAAGVSTTTVLRFCRKLQCEGYS
CCCCHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCH
EFRVRFKLYLEQNEPQQANIGASEIMSFFKSVNNDEFDELLEQAVDIILASERIIFVGAG
HHEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECC
TSGALAKYGARFFSNVGKFSNHIDDPYFPVTNDMARNALAIVLSVSGETEEILRFASQFS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEEECCCCHHHHHHHHHHHC
LHHCKVMSITSHEHSRLAKLADFNLSWHVPQTRIGGVYDITTQIPVIYILESLGRKLARK
HHHEEEEEECCCHHHHHHHHHCCCCEECCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
IS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]