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The map label for this gene is fimH [H]

Identifier: 238896405

GI number: 238896405

Start: 4386276

End: 4387184

Strand: Direct

Name: fimH [H]

Synonym: KP1_4577

Alternate gene names: 238896405

Gene position: 4386276-4387184 (Clockwise)

Preceding gene: 238896404

Following gene: 238896406

Centisome position: 83.57

GC content: 61.5

Gene sequence:

>909_bases
ATGATGAAAAAAATAATCCCCCTGTTCACCACCCTGCTGCTGCTGGGCTGGTCGATGAACGCCTGGTCCTTTGCCTGCAA
AACGGCCACCGGGGCGACGATTCCCATCGGCGGCGGGTCAGCCAACGTCTACGTTAACCTGACCCCGGCGGTGAACGTCG
GGCAAAACCTGGTGGTCGACCTCTCCACGCAGATTTTTTGCCATAACGACTATCCGGAAACGATCACCGACTACGTGACC
CTGCAGCGCGGATCCGCCTATGGCGGTGTGCTGTCGAGTTTTTCAGGCACCGTGAAATATAACGGCACCTCTTACCCGTT
CCCGACCACCACGGAAACCGCGCGGGTGATTTATGATTCACGGACCGATAAACCCTGGCCAGCCGTCCTGTATCTGACGC
CGGTGAGCACTGCCGGTGGAGTGGCCATCACCGCAGGATCGTTAATCGCGGTGCTGATCCTGCATCAGACCAACAACTAC
AATAGCGACTCCTTCCATTTCATCTGGAACATCTACGCCAATAACGACGTGGTGGTCCCCACCGGCGGCTGCGACGTCTC
CGCCCGCGATGTCACCGTCACCCTCCCCGACTACCCGGGATCGATGGCCGTGCCGCTCACCGTCCACTGCGCGCAGAGCC
AGCAGCTGGGGTATTACCTCTCCGGCACCACCGCGGACAGCGCCAACGCGATCTTCACCAATACCGCCTCCGCCTCGCCG
GCGCAGGGGATAGGCGTTCAGCTGACGCGCAACGGCAGCGCCGTCCCGGCGAACAGCACGGTCTCGCTGGGCACCGTCGG
CACCTCGCCGGTCAACCTCGGCCTGACGGCCACCTATGCCCGGACCACAGGCCAGGTTACCGCCGGCAACGTGCAGTCGA
TCATCGGCATCACCTTTGTCTATCAATGA

Upstream 100 bases:

>100_bases
TGCAGGCCAGGGCGCTGTCCGTCAACGGCGGCGCCACGCAAGGCACCATTCAGGCGGTGATTAACGTCACCTATACCTAC
GCCTGAGCCAGGAGAGCATC

Downstream 100 bases:

>100_bases
TGACCGATTATATCCTCTCGCCCTGCTCGCTGGCCGCCCGCGGGTTGAGCCAGCTGATGCTGAACGCCGCGAAGCGGCCC
GTTGAGCTGCCGGTCGAGGG

Product: type 1 fimbrial adhesin precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MMKKIIPLFTTLLLLGWSMNAWSFACKTATGATIPIGGGSANVYVNLTPAVNVGQNLVVDLSTQIFCHNDYPETITDYVT
LQRGSAYGGVLSSFSGTVKYNGTSYPFPTTTETARVIYDSRTDKPWPAVLYLTPVSTAGGVAITAGSLIAVLILHQTNNY
NSDSFHFIWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSMAVPLTVHCAQSQQLGYYLSGTTADSANAIFTNTASASP
AQGIGVQLTRNGSAVPANSTVSLGTVGTSPVNLGLTATYARTTGQVTAGNVQSIIGITFVYQ

Sequences:

>Translated_302_residues
MMKKIIPLFTTLLLLGWSMNAWSFACKTATGATIPIGGGSANVYVNLTPAVNVGQNLVVDLSTQIFCHNDYPETITDYVT
LQRGSAYGGVLSSFSGTVKYNGTSYPFPTTTETARVIYDSRTDKPWPAVLYLTPVSTAGGVAITAGSLIAVLILHQTNNY
NSDSFHFIWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSMAVPLTVHCAQSQQLGYYLSGTTADSANAIFTNTASASP
AQGIGVQLTRNGSAVPANSTVSLGTVGTSPVNLGLTATYARTTGQVTAGNVQSIIGITFVYQ
>Mature_302_residues
MMKKIIPLFTTLLLLGWSMNAWSFACKTATGATIPIGGGSANVYVNLTPAVNVGQNLVVDLSTQIFCHNDYPETITDYVT
LQRGSAYGGVLSSFSGTVKYNGTSYPFPTTTETARVIYDSRTDKPWPAVLYLTPVSTAGGVAITAGSLIAVLILHQTNNY
NSDSFHFIWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSMAVPLTVHCAQSQQLGYYLSGTTADSANAIFTNTASASP
AQGIGVQLTRNGSAVPANSTVSLGTVGTSPVNLGLTATYARTTGQVTAGNVQSIIGITFVYQ

Specific function: Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimb

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790775, Length=301, Percent_Identity=83.7209302325581, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1787779, Length=298, Percent_Identity=47.986577181208, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779
- InterPro:   IPR015243 [H]

Pfam domain/function: PF00419 Fimbrial; PF09160 FimH_man-bind [H]

EC number: NA

Molecular weight: Translated: 31678; Mature: 31678

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKIIPLFTTLLLLGWSMNAWSFACKTATGATIPIGGGSANVYVNLTPAVNVGQNLVVD
CCCHHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEECCCCEEEEEEECCCCCCCCEEEEE
LSTQIFCHNDYPETITDYVTLQRGSAYGGVLSSFSGTVKYNGTSYPFPTTTETARVIYDS
EEEEEEEECCCCCHHHHEEEEECCCCCCCHHHCCCCEEEECCCCCCCCCCCCCEEEEEEC
RTDKPWPAVLYLTPVSTAGGVAITAGSLIAVLILHQTNNYNSDSFHFIWNIYANNDVVVP
CCCCCCCEEEEEEECCCCCCEEEECCCEEEEEEEEECCCCCCCCEEEEEEEEECCEEEEE
TGGCDVSARDVTVTLPDYPGSMAVPLTVHCAQSQQLGYYLSGTTADSANAIFTNTASASP
CCCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEECCCCCC
AQGIGVQLTRNGSAVPANSTVSLGTVGTSPVNLGLTATYARTTGQVTAGNVQSIIGITFV
CCCCCEEEECCCCCCCCCCEEEEECCCCCCEEECEEEEEEECCCCEECCCCCEEEEEEEE
YQ
EC
>Mature Secondary Structure
MMKKIIPLFTTLLLLGWSMNAWSFACKTATGATIPIGGGSANVYVNLTPAVNVGQNLVVD
CCCHHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEECCCCEEEEEEECCCCCCCCEEEEE
LSTQIFCHNDYPETITDYVTLQRGSAYGGVLSSFSGTVKYNGTSYPFPTTTETARVIYDS
EEEEEEEECCCCCHHHHEEEEECCCCCCCHHHCCCCEEEECCCCCCCCCCCCCEEEEEEC
RTDKPWPAVLYLTPVSTAGGVAITAGSLIAVLILHQTNNYNSDSFHFIWNIYANNDVVVP
CCCCCCCEEEEEEECCCCCCEEEECCCEEEEEEEEECCCCCCCCEEEEEEEEECCEEEEE
TGGCDVSARDVTVTLPDYPGSMAVPLTVHCAQSQQLGYYLSGTTADSANAIFTNTASASP
CCCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEECCCCCC
AQGIGVQLTRNGSAVPANSTVSLGTVGTSPVNLGLTATYARTTGQVTAGNVQSIIGITFV
CCCCCEEEECCCCCCCCCCEEEEECCCCCCEEECEEEEEEECCCCEECCCCCEEEEEEEE
YQ
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2890081; 7905476; 7610040; 9278503; 1971261 [H]