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The map label for this gene is pduW [H]

Identifier: 238896328

GI number: 238896328

Start: 4302399

End: 4303613

Strand: Direct

Name: pduW [H]

Synonym: KP1_4491

Alternate gene names: 238896328

Gene position: 4302399-4303613 (Clockwise)

Preceding gene: 238896327

Following gene: 238896329

Centisome position: 81.97

GC content: 62.39

Gene sequence:

>1215_bases
ATGACCTATAAAATCATGGCGATTAACGCCGGCAGCTCCTCCCTGAAGTTTCAGCTGCTTAACATGCCGCAGGGGGCGTT
GCTCTGTCAGGGGTTGATCGAACGTATCGGCCTGCCCGAGGCCCGCTTCACGCTGAAAACGTCGGCACAGAAATGGCAGG
AGACGCTGCCCATCGCCGATCACCATGAGGCAGTGACCCTGCTGCTGGAGGCGCTGACCGGCCGCGGGATCCTGAGCAGC
CTGCAGGAGATCGACGGCGTTGGCCACCGCGTCGCCCACGGCGGCGAACGCTTCAAAGACGCAGCGCTGGTCTGCGACGA
TACCCTGCGGGAGATCGAGCGCCTGGCGGAGCTGGCGCCGTTGCATAACCCGGTCAATGCGCTGGGCATGCGTCTCTTTC
GCCAGCTGTTACCCGCGGTACCGGCGGTGGCGGTTTTTGATACCGCCTTTCACCAGACCCTGGCGCCGGAGGCCTGGCTC
TATCCCCTCCCCTGGCGCTATTACGCCGAGCTGGGCATTCGCCGCTACGGTTTTCACGGTACCAGCCATCACTATGTCAG
CAGCGCGCTGGCGGAAAAGCTGGGCGTACCGCTGAGCGCCCTGCGGGTAGTAAGCTGCCATCTGGGCAATGGCTGTAGCG
TCTGCGCCATCAAAGGCGGGCAGTCGGTGAATACCTCAATGGGCTTTACCCCGCAGTCCGGGGTGATGATGGGCACCCGC
AGCGGCGATATCGACCCGTCGATCCTTCCCTGGCTGGTGGAGAAAGAAGGGAAATCCGCCCTGCAGCTCAGCCAGCTGCT
GAATAATGAATCCGGGCTGCTGGGCGTCTCCGGCGTGTCCTCTGATTACCGCGACGTCGAACAGGCAGCCGACGCCGGCA
ACGAACGGGCGGCTCTGGCGCTGTCGCTGTTTGCCGAACGCATTCGCGCGACTATCGGCAGCTATATCATGCAGATGGGA
GGTCTGGACGCGCTGATCTTTACCGGCGGCATAGGCGAGAATTCCGCCCGGGCGCGGGCGACGATCTGCCGCAATTTGCA
TTTTCTCGGCCTCGCGCTGGACGACGAGAAAAACCAGCGGAGCGCGACCTTTATTCAGGCGGATAATGCGCTGGTCAAAG
TGGCGGTGATCAACACCAATGAAGAGCTAATGATTGCCCGCGACGTCATGCGTCTTGCATTGCCGCAGGCGCGCGAGCTG
GCGGTGTCGGCATAA

Upstream 100 bases:

>100_bases
GGCTCGAGGCGGCGGGCGCCGGACATATCTTTATCACCAGCGCGTTAACCGGCGACGGGCTTGATGACCTGTTCGCCTGC
CTGAATGCAGAGGAATATCA

Downstream 100 bases:

>100_bases
ACGACGCGCCTCCTCTTGCGGAGAATCATGGTAACCGGCGGGTCGCCATGCCACTATGCGCCCTGGCGAAGGTAAGCGGA
AAGGTGAAAACGTGGCTGTT

Product: propionate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHEAVTLLLEALTGRGILSS
LQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPLHNPVNALGMRLFRQLLPAVPAVAVFDTAFHQTLAPEAWL
YPLPWRYYAELGIRRYGFHGTSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTR
SGDIDPSILPWLVEKEGKSALQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALALSLFAERIRATIGSYIMQMG
GLDALIFTGGIGENSARARATICRNLHFLGLALDDEKNQRSATFIQADNALVKVAVINTNEELMIARDVMRLALPQAREL
AVSA

Sequences:

>Translated_404_residues
MTYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHEAVTLLLEALTGRGILSS
LQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPLHNPVNALGMRLFRQLLPAVPAVAVFDTAFHQTLAPEAWL
YPLPWRYYAELGIRRYGFHGTSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTR
SGDIDPSILPWLVEKEGKSALQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALALSLFAERIRATIGSYIMQMG
GLDALIFTGGIGENSARARATICRNLHFLGLALDDEKNQRSATFIQADNALVKVAVINTNEELMIARDVMRLALPQAREL
AVSA
>Mature_403_residues
TYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHEAVTLLLEALTGRGILSSL
QEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPLHNPVNALGMRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLY
PLPWRYYAELGIRRYGFHGTSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTRS
GDIDPSILPWLVEKEGKSALQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALALSLFAERIRATIGSYIMQMGG
LDALIFTGGIGENSARARATICRNLHFLGLALDDEKNQRSATFIQADNALVKVAVINTNEELMIARDVMRLALPQARELA
VSA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family. PduW subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=45.1776649746193, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=42.6767676767677, Blast_Score=296, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.15 [H]

Molecular weight: Translated: 43653; Mature: 43522

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIAD
CEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHCCCCC
HHEAVTLLLEALTGRGILSSLQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAP
CHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
LHNPVNALGMRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLYPLPWRYYAELGIRRYGFHG
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHCCCCC
TSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTR
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECC
SGDIDPSILPWLVEKEGKSALQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALA
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHH
LSLFAERIRATIGSYIMQMGGLDALIFTGGIGENSARARATICRNLHFLGLALDDEKNQR
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCC
SATFIQADNALVKVAVINTNEELMIARDVMRLALPQARELAVSA
CEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
TYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIAD
EEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHCCCCC
HHEAVTLLLEALTGRGILSSLQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAP
CHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
LHNPVNALGMRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLYPLPWRYYAELGIRRYGFHG
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCHHHCCCCC
TSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTR
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECC
SGDIDPSILPWLVEKEGKSALQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALA
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHH
LSLFAERIRATIGSYIMQMGGLDALIFTGGIGENSARARATICRNLHFLGLALDDEKNQR
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCC
SATFIQADNALVKVAVINTNEELMIARDVMRLALPQARELAVSA
CEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA