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The map label for this gene is pduP [H]

Identifier: 238896322

GI number: 238896322

Start: 4297189

End: 4298577

Strand: Direct

Name: pduP [H]

Synonym: KP1_4485

Alternate gene names: 238896322

Gene position: 4297189-4298577 (Clockwise)

Preceding gene: 238896321

Following gene: 238896323

Centisome position: 81.87

GC content: 61.27

Gene sequence:

>1389_bases
ATGAATACAGCAGAACTGGAAACCCTTATCCGCACCATCCTCAGTGAAAAGCTCGCGCCGACGCCCCCTGCCCCTCAGCA
AGAGCAGGGCATTTTCTGCGATGTCGGCAGCGCCATCGACGCCGCTCATCAGGCTTTTCTCCGCTATCAGCAGTGTCCGC
TAAAAACCCGCAGCGCCATTATCAGCGCCCTGCGGGAGACGCTGGCCCCCGAGCTGGCGACGCTGGCGGAAGAGAGCGCC
ACGGAAACCGGCATGGGCAACAAAGAAGATAAATATCTGAAAAATAAAGCCGCTCTTGAAAACACGCCGGGCATAGAGGA
TCTCACTACCAGCGCCCTCACCGGCGATGGCGGGATGGTGCTGTTTGAGTACTCGCCGTTCGGGGTTATTGGCGCCGTGG
CGCCCAGCACCAACCCAACGGAAACCATTATCAACAACAGTATCAGCATGCTGGCGGCGGGTAACAGCGTCTATTTCAGC
CCCCATCCCGGCGCGAAAAAGGTCTCGTTGAAGCTTATCGCCAGGATCGAAGAGATCGCCTACCGCTGCAGCGGGATCCG
TAACCTGGTGGTGACCGTTGCCGAGCCGACCTTTGAAGCCACCCAGCAAATGATGTCCCACCCGCTGATTGCCGTTCTGG
CTATCACCGGCGGCCCTGGCATTGTGGCGATGGGCATGAAAAGCGGTAAAAAAGTGATCGGCGCTGGCGCCGGCAATCCG
CCGTGCATCGTTGATGAAACCGCCGATCTCGTCAAAGCCGCCGAAGATATCATCAGCGGCGCCGCCTTCGATTACAACCT
GCCCTGTATCGCCGAAAAAAGCCTGATCGTCGTCGCCTCCGTCGCTGACCGCCTGATCCAGCAGATGCAGGATTTTGACG
CGCTGCTGTTGAGCCGACAGGAGGCCGATACCCTGCGTGCCGTCTGCCTGCCCGACGGCGCGGCGAATAAAAAACTGGTC
GGTAAAAGCCCGGCTGCGCTGCTGGCGGCGGCGGGTCTCGCCGTTCCGCCTCGCCCCCCTCGCCTGCTGATAGCCGAGGT
GGAGGCGAACGCCCCCTGGGTGACCTGCGAGCAGCTGATGCCGGTGCTGCCGATCGTCAGGGTCGCCGACTTTGACAGCG
CCCTGGCGCTGGCCCTGCGCGTTGAGGAGGGTCTGCACCACACCGCCATTATGCACTCGCAGAATGTCTCGCGGCTCAAT
CTGGCGGCACGCACCCTGCAGACCTCCATTTTTGTCAAAAATGGCCCGTCTTACGCGGGAATCGGCGTCGGCGGCGAAGG
GTTTACCACCTTCACCATCGCCACGCCAACCGGAGAAGGCACCACCTCCGCGCGGACGTTCGCCCGCCTGCGGCGCTGCG
TGTTGACCAACGGTTTTTCCATTCGCTAA

Upstream 100 bases:

>100_bases
GCCAGCTAATAGCCGGCCTCGGCATTAGCGGCGGCAGCGTCGAGCAGGATATGGCTATTGCACAGGCTGCCATGGCGGCC
ATTAACGTGAGAACTCATCA

Downstream 100 bases:

>100_bases
CCGGGGGCGCCATGCATACCTTTTCTCTGCAAACGCGCCTCTACAGCGGCCCGGGCAGCCTGGCCGCGCTGCAGCGCTTT
AGCCATCAGCACATCTGGAT

Product: propanediol utilization CoA-dependent propionaldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNTAELETLIRTILSEKLAPTPPAPQQEQGIFCDVGSAIDAAHQAFLRYQQCPLKTRSAIISALRETLAPELATLAEESA
TETGMGNKEDKYLKNKAALENTPGIEDLTTSALTGDGGMVLFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFS
PHPGAKKVSLKLIARIEEIAYRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGKKVIGAGAGNP
PCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQDFDALLLSRQEADTLRAVCLPDGAANKKLV
GKSPAALLAAAGLAVPPRPPRLLIAEVEANAPWVTCEQLMPVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLN
LAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARLRRCVLTNGFSIR

Sequences:

>Translated_462_residues
MNTAELETLIRTILSEKLAPTPPAPQQEQGIFCDVGSAIDAAHQAFLRYQQCPLKTRSAIISALRETLAPELATLAEESA
TETGMGNKEDKYLKNKAALENTPGIEDLTTSALTGDGGMVLFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFS
PHPGAKKVSLKLIARIEEIAYRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGKKVIGAGAGNP
PCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQDFDALLLSRQEADTLRAVCLPDGAANKKLV
GKSPAALLAAAGLAVPPRPPRLLIAEVEANAPWVTCEQLMPVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLN
LAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARLRRCVLTNGFSIR
>Mature_462_residues
MNTAELETLIRTILSEKLAPTPPAPQQEQGIFCDVGSAIDAAHQAFLRYQQCPLKTRSAIISALRETLAPELATLAEESA
TETGMGNKEDKYLKNKAALENTPGIEDLTTSALTGDGGMVLFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFS
PHPGAKKVSLKLIARIEEIAYRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGKKVIGAGAGNP
PCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQDFDALLLSRQEADTLRAVCLPDGAANKKLV
GKSPAALLAAAGLAVPPRPPRLLIAEVEANAPWVTCEQLMPVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLN
LAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARLRRCVLTNGFSIR

Specific function: May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788797, Length=469, Percent_Identity=46.6950959488273, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1787493, Length=362, Percent_Identity=32.5966850828729, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787558, Length=430, Percent_Identity=24.4186046511628, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323822, Length=450, Percent_Identity=24.2222222222222, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=307, Percent_Identity=23.7785016286645, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012408
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: NA

Molecular weight: Translated: 48715; Mature: 48715

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAELETLIRTILSEKLAPTPPAPQQEQGIFCDVGSAIDAAHQAFLRYQQCPLKTRSAI
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHH
ISALRETLAPELATLAEESATETGMGNKEDKYLKNKAALENTPGIEDLTTSALTGDGGMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHEECCCCEE
LFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFSPHPGAKKVSLKLIARIEEIA
EEEECCCCEEEECCCCCCCHHHHHCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHH
YRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGKKVIGAGAGNP
HHHHCCCEEEEEECCCCHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCCEEEECCCCCC
PCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQDFDALLLSRQ
CEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EADTLRAVCLPDGAANKKLVGKSPAALLAAAGLAVPPRPPRLLIAEVEANAPWVTCEQLM
HHHHEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEHHHHH
PVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLNLAARTLQTSIFVKNGPSYAG
HHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCEEE
IGVGGEGFTTFTIATPTGEGTTSARTFARLRRCVLTNGFSIR
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTAELETLIRTILSEKLAPTPPAPQQEQGIFCDVGSAIDAAHQAFLRYQQCPLKTRSAI
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHH
ISALRETLAPELATLAEESATETGMGNKEDKYLKNKAALENTPGIEDLTTSALTGDGGMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHEECCCCEE
LFEYSPFGVIGAVAPSTNPTETIINNSISMLAAGNSVYFSPHPGAKKVSLKLIARIEEIA
EEEECCCCEEEECCCCCCCHHHHHCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHH
YRCSGIRNLVVTVAEPTFEATQQMMSHPLIAVLAITGGPGIVAMGMKSGKKVIGAGAGNP
HHHHCCCEEEEEECCCCHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCCEEEECCCCCC
PCIVDETADLVKAAEDIISGAAFDYNLPCIAEKSLIVVASVADRLIQQMQDFDALLLSRQ
CEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EADTLRAVCLPDGAANKKLVGKSPAALLAAAGLAVPPRPPRLLIAEVEANAPWVTCEQLM
HHHHEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEHHHHH
PVLPIVRVADFDSALALALRVEEGLHHTAIMHSQNVSRLNLAARTLQTSIFVKNGPSYAG
HHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCEEE
IGVGGEGFTTFTIATPTGEGTTSARTFARLRRCVLTNGFSIR
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]