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The map label for this gene is cbiT [H]

Identifier: 238896299

GI number: 238896299

Start: 4279529

End: 4280098

Strand: Reverse

Name: cbiT [H]

Synonym: KP1_4460

Alternate gene names: 238896299

Gene position: 4280098-4279529 (Counterclockwise)

Preceding gene: 238896300

Following gene: 238896298

Centisome position: 81.55

GC content: 64.39

Gene sequence:

>570_bases
ATGAAAGATGAGCTGTTTTTGCGCGGCGCCCAGGTGCCGATGACCAAAGAGGCCGTGCGCGCGCTGGCGCTGGCGAAGCT
GGAGCTGCACCGGGCGCGCCATCTGATTGATATCGGCGCGGGCACCGGCAGCGTCAGCATTGAGGCTGCTCTACAGAACC
CGGCGCTGCGGGTGACGGCGATTGAGCGTCAGGCCGACGCGCTGCGCCTGCTGGCGGAGAACCGGCAGCGCTTTGGCTGC
GACAACATCGCTATCGTGGCGGGCGTTGCGCCGCTGGCGGTCGCCGACAAAGCCGACGCGATCTTTATGGGGGGCAGCGG
CGGCCACCTGACGGCGCTGATCGACTGGTCGCTGGCGCAGCTGCATCCTGGCGGCCGGCTGGTGATGACTTTTATTTTGC
AGGAAAACCTTCATAGCGCCCTGGCGCACCTGCGGCAGAGCGGCATCCACGAGGTGGACTGCCAGCAGCTGGCGGTCTCC
ACCCTGGCTACCCTGGGTAGCGGCCACTACTTCAAACCCCATAATCCCGTTTTTGTCATCGCCTGTCAGAAGGAAGAAAA
CCATGGCTGA

Upstream 100 bases:

>100_bases
GTGATAGGCGAGAACCTGGCGATGGAAAACGAGCGGATCCACTGGCTGCCGGTCAGCGCCGTGGAGGACGAATATGAGAT
GAATGCGGTGGTGATCCTCG

Downstream 100 bases:

>100_bases
GACTTTTGATCCCCATTGCGTGTGGTTCGTCGGCGCCGGTCCGGGCGATCGCGAACTGATTACTCTCAAAGGCTACCGTC
TGCTACAGCAGGCGCAGGTA

Product: cobalt-precorrin-6Y C(15)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKDELFLRGAQVPMTKEAVRALALAKLELHRARHLIDIGAGTGSVSIEAALQNPALRVTAIERQADALRLLAENRQRFGC
DNIAIVAGVAPLAVADKADAIFMGGSGGHLTALIDWSLAQLHPGGRLVMTFILQENLHSALAHLRQSGIHEVDCQQLAVS
TLATLGSGHYFKPHNPVFVIACQKEENHG

Sequences:

>Translated_189_residues
MKDELFLRGAQVPMTKEAVRALALAKLELHRARHLIDIGAGTGSVSIEAALQNPALRVTAIERQADALRLLAENRQRFGC
DNIAIVAGVAPLAVADKADAIFMGGSGGHLTALIDWSLAQLHPGGRLVMTFILQENLHSALAHLRQSGIHEVDCQQLAVS
TLATLGSGHYFKPHNPVFVIACQKEENHG
>Mature_189_residues
MKDELFLRGAQVPMTKEAVRALALAKLELHRARHLIDIGAGTGSVSIEAALQNPALRVTAIERQADALRLLAENRQRFGC
DNIAIVAGVAPLAVADKADAIFMGGSGGHLTALIDWSLAQLHPGGRLVMTFILQENLHSALAHLRQSGIHEVDCQQLAVS
TLATLGSGHYFKPHNPVFVIACQKEENHG

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Bacterial-type CbiT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014008
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 1.-.-.-

Molecular weight: Translated: 20275; Mature: 20275

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDELFLRGAQVPMTKEAVRALALAKLELHRARHLIDIGAGTGSVSIEAALQNPALRVTA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCEEEEE
IERQADALRLLAENRQRFGCDNIAIVAGVAPLAVADKADAIFMGGSGGHLTALIDWSLAQ
EHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEECCCCCEEEEEEECHHHH
LHPGGRLVMTFILQENLHSALAHLRQSGIHEVDCQQLAVSTLATLGSGHYFKPHNPVFVI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEE
ACQKEENHG
EEECCCCCC
>Mature Secondary Structure
MKDELFLRGAQVPMTKEAVRALALAKLELHRARHLIDIGAGTGSVSIEAALQNPALRVTA
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCEEEEE
IERQADALRLLAENRQRFGCDNIAIVAGVAPLAVADKADAIFMGGSGGHLTALIDWSLAQ
EHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEECCCCCEEEEEEECHHHH
LHPGGRLVMTFILQENLHSALAHLRQSGIHEVDCQQLAVSTLATLGSGHYFKPHNPVFVI
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECCCCCEEEE
ACQKEENHG
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]