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The map label for this gene is fucR [H]

Identifier: 238896277

GI number: 238896277

Start: 4260788

End: 4261498

Strand: Direct

Name: fucR [H]

Synonym: KP1_4436

Alternate gene names: 238896277

Gene position: 4260788-4261498 (Clockwise)

Preceding gene: 238896276

Following gene: 238896282

Centisome position: 81.18

GC content: 59.77

Gene sequence:

>711_bases
ATGAAAGCAGCCCGCCAGCAGGCGATCGTCGATCTCCTGATCACCCACAGCAGCCTGACCACCGAAACGTTGTCAAAACA
GCTCAACGTCAGCAGGGAAACTATTCGCCGCGATCTGAGCGAGCTGCAGGCGCAGGGCAAAGTGCTGCGTAACCACGGCC
GGGCCAAAGTGATCCACCAGCGCAGCCAGGACAGCGGCGATCCTTTCCACATGCGCCTGAAAAGCCATTACGCGCATAAA
GCCGACATCGCCCGCGAAGCGCTGGCCTGGATTGACGAAGGGATGGTGATCGCCCTCGATGCCAGCTCCACCTGCTGGTA
TCTCGCCCGCCAGCTGCCGGACCGCCCGCTGCACGTCTTTACCAACAGCCAGCCCATCTGCCAGGAGCTGGCCAAACGCG
ACCAGATCACGCTCACCTGCTCCGGCGGCACTCTGCAGCGGAAATATGGCTGCTACGTGAACCCGGCGCTGATTTCCCAG
CTGAAATCGCTGGAGATCGATCTGTTTATTTTTTCCTGCGAAGGCATCGACCCGCAGGGCGCGCTGTGGGACTCCAATGC
GTTCAATGCCGACTTCAAATCGATCCTGCTTAAGCGGGCGGCGCAGTCGCTACTGCTGATCGACAAAAGCAAGTTCAACC
GCTCCGGCGAGGCGAGGATTGGTCATCTGGATGACGTGACGCATATTGTGTCGGATGCGCCGCAGCCTTAA

Upstream 100 bases:

>100_bases
AAGTACGGAAATATCCTTTTAAAAAAAGGAGTCACGCCGTAATCTCATGCCGGAGCGTCTGCCTGATGCAGACGCTCAAT
CAATGATGGGATGAGAATAA

Downstream 100 bases:

>100_bases
GGGGAAGGCCGGAGGACGCGCACGCGTCTCCGGCCTGAGGGGGAAGGATTAACGCTCGTCGCGACGTCCGCCGACGGCGG
CCCACAGGCGGCGCACGTGA

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKAARQQAIVDLLITHSSLTTETLSKQLNVSRETIRRDLSELQAQGKVLRNHGRAKVIHQRSQDSGDPFHMRLKSHYAHK
ADIAREALAWIDEGMVIALDASSTCWYLARQLPDRPLHVFTNSQPICQELAKRDQITLTCSGGTLQRKYGCYVNPALISQ
LKSLEIDLFIFSCEGIDPQGALWDSNAFNADFKSILLKRAAQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQP

Sequences:

>Translated_236_residues
MKAARQQAIVDLLITHSSLTTETLSKQLNVSRETIRRDLSELQAQGKVLRNHGRAKVIHQRSQDSGDPFHMRLKSHYAHK
ADIAREALAWIDEGMVIALDASSTCWYLARQLPDRPLHVFTNSQPICQELAKRDQITLTCSGGTLQRKYGCYVNPALISQ
LKSLEIDLFIFSCEGIDPQGALWDSNAFNADFKSILLKRAAQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQP
>Mature_236_residues
MKAARQQAIVDLLITHSSLTTETLSKQLNVSRETIRRDLSELQAQGKVLRNHGRAKVIHQRSQDSGDPFHMRLKSHYAHK
ADIAREALAWIDEGMVIALDASSTCWYLARQLPDRPLHVFTNSQPICQELAKRDQITLTCSGGTLQRKYGCYVNPALISQ
LKSLEIDLFIFSCEGIDPQGALWDSNAFNADFKSILLKRAAQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQP

Specific function: Transcriptional activator of the fuc operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=83.4042553191489, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=31.4410480349345, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789829, Length=233, Percent_Identity=27.8969957081545, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=26.1802575107296, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=26.4069264069264, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787540, Length=232, Percent_Identity=25.4310344827586, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=21.6450216450216, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789519, Length=233, Percent_Identity=24.0343347639485, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790753, Length=233, Percent_Identity=22.7467811158798, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI226510968, Length=241, Percent_Identity=26.5560165975104, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26429; Mature: 26429

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARQQAIVDLLITHSSLTTETLSKQLNVSRETIRRDLSELQAQGKVLRNHGRAKVIHQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHC
RSQDSGDPFHMRLKSHYAHKADIAREALAWIDEGMVIALDASSTCWYLARQLPDRPLHVF
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEE
TNSQPICQELAKRDQITLTCSGGTLQRKYGCYVNPALISQLKSLEIDLFIFSCEGIDPQG
ECCCHHHHHHHCCCCEEEEECCCCEECCCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAFNADFKSILLKRAAQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQP
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAARQQAIVDLLITHSSLTTETLSKQLNVSRETIRRDLSELQAQGKVLRNHGRAKVIHQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHC
RSQDSGDPFHMRLKSHYAHKADIAREALAWIDEGMVIALDASSTCWYLARQLPDRPLHVF
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEE
TNSQPICQELAKRDQITLTCSGGTLQRKYGCYVNPALISQLKSLEIDLFIFSCEGIDPQG
ECCCHHHHHHHCCCCEEEEECCCCEECCCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAFNADFKSILLKRAAQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQP
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]