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The map label for this gene is xni

Identifier: 238896270

GI number: 238896270

Start: 4252457

End: 4253212

Strand: Direct

Name: xni

Synonym: KP1_4429

Alternate gene names: 238896270

Gene position: 4252457-4253212 (Clockwise)

Preceding gene: 238896269

Following gene: 238896273

Centisome position: 81.02

GC content: 67.46

Gene sequence:

>756_bases
GTGGCTGTTCATCTGTTAATCGTCGACGCGTTAAATCTGATCCGCCGCATCCACGCGGTGCAGGGTTCACCCTGCGTCGA
TACCTGCCTGCATGCCCTGGAGCAGCTGATTGTCCACAGTCAGCCCACCCACGCGGTGGCGGTGTTCGATGATGAGGATC
GCGCCCACGGCTGGCGCCACCAGCGCCTGCCGGAGTACAAAGCCGGCCGCGCGCCGATGCCGGAGACGCTGGTCGCCGAG
ATGCCGGCGCTGCGGGCCGCCTTCGAACAGCGGGGGATCCGCTGCTGGGCCTCGCCGGGCAGCGAAGCGGACGATCTCGC
CGCCACCCTGGCGGTAAAGGTGGCCCAGGCGGGCCATCAGGCCACCATCGTCTCCACCGACAAAGGCTATTGCCAGCTGC
TGTCGCCCACCATCCGCATCCGCGACTACTTTCAGAAGCGCTGGCTGGACGCCCCCTTCATCGCCAGCGAGTTCGGCGTC
ACCCCGGAGCAGCTGGCGGATTACTGGGGGCTGGCGGGGATCAGCAGCTCGAAGGTGCCGGGCGTGGCGGGCATTGGACC
CAAAAGCGCCGCCCAGCTGCTGAACGAGTTTCAGGACCTGGAGGGGCTGTACGCCCGTCTGGCCGAGGTCCCGGAGAAGT
GGCGCAAAAAGCTGGCCGCGCATCAGGAGATGGCCTTCACCTGCCGGGAGGTGGCCCGCCTGCAGACCGACCTCCAGCTG
GACGGCAATCTGCAGCAGCTGCGGCTGACGCGCTGA

Upstream 100 bases:

>100_bases
TTAGCGAAATTTGCGCGTTATCTTCCTGATTGTTCAGGCGCAGATAGCCTCGATCTGATGGCGATGTTACCCTAAAGACG
CTGAGAATAAGGGGGTATCT

Downstream 100 bases:

>100_bases
CCATCGTTAAGAGGTGCGCCGGTGCAGGGTAACTGCCTGCTTTACCCGGGCCAGGCAATCACCAGGCCGCCTGATATAAC
CCGACGATATCCGCCAGGCT

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAVHLLIVDALNLIRRIHAVQGSPCVDTCLHALEQLIVHSQPTHAVAVFDDEDRAHGWRHQRLPEYKAGRAPMPETLVAE
MPALRAAFEQRGIRCWASPGSEADDLAATLAVKVAQAGHQATIVSTDKGYCQLLSPTIRIRDYFQKRWLDAPFIASEFGV
TPEQLADYWGLAGISSSKVPGVAGIGPKSAAQLLNEFQDLEGLYARLAEVPEKWRKKLAAHQEMAFTCREVARLQTDLQL
DGNLQQLRLTR

Sequences:

>Translated_251_residues
MAVHLLIVDALNLIRRIHAVQGSPCVDTCLHALEQLIVHSQPTHAVAVFDDEDRAHGWRHQRLPEYKAGRAPMPETLVAE
MPALRAAFEQRGIRCWASPGSEADDLAATLAVKVAQAGHQATIVSTDKGYCQLLSPTIRIRDYFQKRWLDAPFIASEFGV
TPEQLADYWGLAGISSSKVPGVAGIGPKSAAQLLNEFQDLEGLYARLAEVPEKWRKKLAAHQEMAFTCREVARLQTDLQL
DGNLQQLRLTR
>Mature_250_residues
AVHLLIVDALNLIRRIHAVQGSPCVDTCLHALEQLIVHSQPTHAVAVFDDEDRAHGWRHQRLPEYKAGRAPMPETLVAEM
PALRAAFEQRGIRCWASPGSEADDLAATLAVKVAQAGHQATIVSTDKGYCQLLSPTIRIRDYFQKRWLDAPFIASEFGVT
PEQLADYWGLAGISSSKVPGVAGIGPKSAAQLLNEFQDLEGLYARLAEVPEKWRKKLAAHQEMAFTCREVARLQTDLQLD
GNLQQLRLTR

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Escherichia coli, GI226510970, Length=251, Percent_Identity=82.8685258964143, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1790294, Length=261, Percent_Identity=32.5670498084291, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XNI_KLEP3 (B5XUZ0)

Other databases:

- EMBL:   CP000964
- RefSeq:   YP_002236839.1
- ProteinModelPortal:   B5XUZ0
- SMR:   B5XUZ0
- GeneID:   6939794
- GenomeReviews:   CP000964_GR
- KEGG:   kpe:KPK_0970
- HOGENOM:   HBG701384
- OMA:   HGEKVTI
- ProtClustDB:   PRK09482
- HAMAP:   MF_01192
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR003583
- InterPro:   IPR022895
- SMART:   SM00475
- SMART:   SM00278
- SMART:   SM00279

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; SSF47807 5_3_exo_C

EC number: 3.1.11.- [C]

Molecular weight: Translated: 27821; Mature: 27690

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHLLIVDALNLIRRIHAVQGSPCVDTCLHALEQLIVHSQPTHAVAVFDDEDRAHGWRH
CEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCHH
QRLPEYKAGRAPMPETLVAEMPALRAAFEQRGIRCWASPGSEADDLAATLAVKVAQAGHQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
ATIVSTDKGYCQLLSPTIRIRDYFQKRWLDAPFIASEFGVTPEQLADYWGLAGISSSKVP
EEEEECCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCC
GVAGIGPKSAAQLLNEFQDLEGLYARLAEVPEKWRKKLAAHQEMAFTCREVARLQTDLQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGNLQQLRLTR
CCCHHHHCCCC
>Mature Secondary Structure 
AVHLLIVDALNLIRRIHAVQGSPCVDTCLHALEQLIVHSQPTHAVAVFDDEDRAHGWRH
EEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCHH
QRLPEYKAGRAPMPETLVAEMPALRAAFEQRGIRCWASPGSEADDLAATLAVKVAQAGHQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
ATIVSTDKGYCQLLSPTIRIRDYFQKRWLDAPFIASEFGVTPEQLADYWGLAGISSSKVP
EEEEECCCCHHHHHCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCC
GVAGIGPKSAAQLLNEFQDLEGLYARLAEVPEKWRKKLAAHQEMAFTCREVARLQTDLQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGNLQQLRLTR
CCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA