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The map label for this gene is zraR [H]

Identifier: 238896269

GI number: 238896269

Start: 4250417

End: 4252360

Strand: Direct

Name: zraR [H]

Synonym: KP1_4428

Alternate gene names: 238896269

Gene position: 4250417-4252360 (Clockwise)

Preceding gene: 238896260

Following gene: 238896270

Centisome position: 80.98

GC content: 65.43

Gene sequence:

>1944_bases
ATGCTGAACCCAGAATCCCCTTCCACCGCTCCCGCGCTGATCGACCCGGCGTCGAAGGCCTTCCAGAGCCTGCTGGACAA
ACTCGCGCCAACGGAGGCGACCGTGCTGATCGTGGGCGAAACCGGCACCGGCAAGGAGGTGGTGGCCCGCTATCTCCATC
ATCACAGCGCCCGTCGCCAGCAGCCGTTTCTGGCCGTTAACTGCGGCGCGCTGACCGAGAGCCTCGCCGAAGCTGAACTG
TTCGGCCATGAGAAAGGCGCCTTCACCGGCGCGCAGCAGGGACAGCCCGGCTGGTTTGAAGCCGCGGAAGGGGGGACGCT
GCTGCTGGACGAGATCGGCGAATTAAGCCTGCCGCTGCAGGTCAAGCTGCTGCGAGTGCTGCAGGAGCGTGAAATTACCC
GCGTCGGCTCACGCAAAGCGATTAAAGTGAATGTCCGGGTGATTGCCGCCACCCACGTTGACCTGGCCCAGGCGATCCGC
GAGCGCCGCTTTCGCGAGGATCTCTACTATCGACTGAATATCGCGGTGGTGCCGCTGCCGCCGCTGCGCCAGCGTCGGCA
GGATATCCCGCTGCTGGCGCACCACTTTTTATCACTCTACGCCCGGCGCCTCGGGCGGCCAACCCTGCGTCTGGCGCCGG
AATCACTGGCCCGGCTGATGGACTATTCGTGGCCGGGCAATATTCGCGAGCTGGAAAACACCCTGCACAACGCGGTGCTG
CTCAGTAAAGAAGAGGAGATCAGTCCTGCCCAGCTGCGCCTGGCGACGCTCAACGACGCCCCGGGGCCGGCGAGCGATCA
TGAACTGGACGACTTTATTCGCCACCAGCTGGCGCTTCCCGGCGAGCCGCTGTGGCAGCGAGTGACCAGCGCCCTGATTC
GCCACGCCATGGCGCATTGCGACGATAACCAGAGCCAGGCGGCCGCGCTGTTGGGGATCAGCCGGCATACCTTGCGCACC
CAGCTCGCTAACCTCGGGCTGATCAAAAGCCGCCGCCGCCCGCCTGCGCCGCCGCGGGCGTTCGCCAACGCAGCCGGGGC
CGATCGCGAACTGCGCATTGGCTACCAGCGCTTCGGCAGCCTCGGGATCCTGAAAGCCCGTCAGAGTCTGGAAACCGCCT
TCGCCAGCCTCGGCGTCAACGTGCTGTGGAGTGAGTTTCCTGCCGGACCGCAGCTCCTCCATGCCCTCGCCTGCAACGAG
ATCGACTTCGGCACCACCGGAGAAGCGCCGCCGGTGTTTGCCCAGGCCAGCAATAGCGAACTGATGTACGTGGCGTGGGA
GCCGCCGGCGCCGCGCAGCGTGGCGATGGTCGTCCCGCAGGAGAGCGACATTCGCCAGCTCAGCGATCTGCGCGGTAAAC
GCATCGCCCTCAATAAAGGGTCGAATGTCCACTGGCTGCTGCTGCAGATCCTCGAGGACGCCGGCCTGGGTCTGAACGAT
GTGCGGGTGGTCTATACCCCGCCGAAATATCCGCTGACCGCCAGCGACTATCTGGCGGTTGACGCCTGGATGATGTGGGA
TCCGCTGCTCAGCGACGCCGAACACACCGGCGAACTGCGGGTGGTCGCCAGCGGCGAAGGCCGGGTCAACAACCATCAGT
TTTATCTTTCGCGACGGGACTACCTCGCTCAGCATGGCGATATCATGCGCCGCCTGCTGACGGAGCTGACCCACACCGGG
CAGTTTATCGACTCGCATCGCGGCGAAGCGGCCCGCTTACTCTCGGCAGAGCTGGGGATCGACGCCCGGTCGCTGAGTAT
TGCCCTCGCCCGCCGCAGCCATCGCCCGCGGCCGATGGATCTGTCGGTGATCCGCGCCCAGCAGACCATCGCCGATCGCT
TTTACGCCCTCGGGCTTATCGCCAAACCGGTCCCGGTGCGCGAAGCGGTGTGGTACGGCGAACCCGCGCCGGACGTCATC
AGACCGCTGATGGCGGTCAGTTAG

Upstream 100 bases:

>100_bases
CGCATCCGCTGGCGCATTTGCAACAGCCGCGGGCCTTCCCCCTCTGGTTTCTGCGGCCGCCGCAGGATAAGTTCAGAGCG
TCAACGATCGGAGGCCCGCT

Downstream 100 bases:

>100_bases
CGAAATTTGCGCGTTATCTTCCTGATTGTTCAGGCGCAGATAGCCTCGATCTGATGGCGATGTTACCCTAAAGACGCTGA
GAATAAGGGGGTATCTGTGG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MLNPESPSTAPALIDPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQQPFLAVNCGALTESLAEAEL
FGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQVKLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIR
ERRFREDLYYRLNIAVVPLPPLRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVL
LSKEEEISPAQLRLATLNDAPGPASDHELDDFIRHQLALPGEPLWQRVTSALIRHAMAHCDDNQSQAAALLGISRHTLRT
QLANLGLIKSRRRPPAPPRAFANAAGADRELRIGYQRFGSLGILKARQSLETAFASLGVNVLWSEFPAGPQLLHALACNE
IDFGTTGEAPPVFAQASNSELMYVAWEPPAPRSVAMVVPQESDIRQLSDLRGKRIALNKGSNVHWLLLQILEDAGLGLND
VRVVYTPPKYPLTASDYLAVDAWMMWDPLLSDAEHTGELRVVASGEGRVNNHQFYLSRRDYLAQHGDIMRRLLTELTHTG
QFIDSHRGEAARLLSAELGIDARSLSIALARRSHRPRPMDLSVIRAQQTIADRFYALGLIAKPVPVREAVWYGEPAPDVI
RPLMAVS

Sequences:

>Translated_647_residues
MLNPESPSTAPALIDPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQQPFLAVNCGALTESLAEAEL
FGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQVKLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIR
ERRFREDLYYRLNIAVVPLPPLRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVL
LSKEEEISPAQLRLATLNDAPGPASDHELDDFIRHQLALPGEPLWQRVTSALIRHAMAHCDDNQSQAAALLGISRHTLRT
QLANLGLIKSRRRPPAPPRAFANAAGADRELRIGYQRFGSLGILKARQSLETAFASLGVNVLWSEFPAGPQLLHALACNE
IDFGTTGEAPPVFAQASNSELMYVAWEPPAPRSVAMVVPQESDIRQLSDLRGKRIALNKGSNVHWLLLQILEDAGLGLND
VRVVYTPPKYPLTASDYLAVDAWMMWDPLLSDAEHTGELRVVASGEGRVNNHQFYLSRRDYLAQHGDIMRRLLTELTHTG
QFIDSHRGEAARLLSAELGIDARSLSIALARRSHRPRPMDLSVIRAQQTIADRFYALGLIAKPVPVREAVWYGEPAPDVI
RPLMAVS
>Mature_647_residues
MLNPESPSTAPALIDPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQQPFLAVNCGALTESLAEAEL
FGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQVKLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIR
ERRFREDLYYRLNIAVVPLPPLRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVL
LSKEEEISPAQLRLATLNDAPGPASDHELDDFIRHQLALPGEPLWQRVTSALIRHAMAHCDDNQSQAAALLGISRHTLRT
QLANLGLIKSRRRPPAPPRAFANAAGADRELRIGYQRFGSLGILKARQSLETAFASLGVNVLWSEFPAGPQLLHALACNE
IDFGTTGEAPPVFAQASNSELMYVAWEPPAPRSVAMVVPQESDIRQLSDLRGKRIALNKGSNVHWLLLQILEDAGLGLND
VRVVYTPPKYPLTASDYLAVDAWMMWDPLLSDAEHTGELRVVASGEGRVNNHQFYLSRRDYLAQHGDIMRRLLTELTHTG
QFIDSHRGEAARLLSAELGIDARSLSIALARRSHRPRPMDLSVIRAQQTIADRFYALGLIAKPVPVREAVWYGEPAPDVI
RPLMAVS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=47.4006116207951, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=44.3425076452599, Blast_Score=266, Evalue=4e-72,
Organism=Escherichia coli, GI87082117, Length=229, Percent_Identity=56.7685589519651, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790299, Length=327, Percent_Identity=44.3425076452599, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=42.4050632911392, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1788905, Length=294, Percent_Identity=45.2380952380952, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789087, Length=320, Percent_Identity=43.4375, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1786524, Length=306, Percent_Identity=44.4444444444444, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082152, Length=230, Percent_Identity=48.2608695652174, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=40.5063291139241, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081803, Length=298, Percent_Identity=37.5838926174497, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=241, Percent_Identity=41.9087136929461, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI87081858, Length=238, Percent_Identity=34.453781512605, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789828, Length=340, Percent_Identity=31.7647058823529, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 71627; Mature: 71627

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPESPSTAPALIDPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQ
CCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHC
QPFLAVNCGALTESLAEAELFGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQ
CCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCHH
VKLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIRERRFREDLYYRLNIAVVPLP
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHEEEEEEEEECCC
PLRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVL
CHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHHHEE
LSKEEEISPAQLRLATLNDAPGPASDHELDDFIRHQLALPGEPLWQRVTSALIRHAMAHC
ECCCCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
DDNQSQAAALLGISRHTLRTQLANLGLIKSRRRPPAPPRAFANAAGADRELRIGYQRFGS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHCCCCCCCEEECHHHHCC
LGILKARQSLETAFASLGVNVLWSEFPAGPQLLHALACNEIDFGTTGEAPPVFAQASNSE
CHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCE
LMYVAWEPPAPRSVAMVVPQESDIRQLSDLRGKRIALNKGSNVHWLLLQILEDAGLGLND
EEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
VRVVYTPPKYPLTASDYLAVDAWMMWDPLLSDAEHTGELRVVASGEGRVNNHQFYLSRRD
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEHHH
YLAQHGDIMRRLLTELTHTGQFIDSHRGEAARLLSAELGIDARSLSIALARRSHRPRPMD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
LSVIRAQQTIADRFYALGLIAKPVPVREAVWYGEPAPDVIRPLMAVS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLNPESPSTAPALIDPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQ
CCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHC
QPFLAVNCGALTESLAEAELFGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQ
CCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCCHH
VKLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIRERRFREDLYYRLNIAVVPLP
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHEEEEEEEEECCC
PLRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVL
CHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCCCHHHHHHHHHHHEE
LSKEEEISPAQLRLATLNDAPGPASDHELDDFIRHQLALPGEPLWQRVTSALIRHAMAHC
ECCCCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
DDNQSQAAALLGISRHTLRTQLANLGLIKSRRRPPAPPRAFANAAGADRELRIGYQRFGS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHCCCCCCCEEECHHHHCC
LGILKARQSLETAFASLGVNVLWSEFPAGPQLLHALACNEIDFGTTGEAPPVFAQASNSE
CHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCE
LMYVAWEPPAPRSVAMVVPQESDIRQLSDLRGKRIALNKGSNVHWLLLQILEDAGLGLND
EEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
VRVVYTPPKYPLTASDYLAVDAWMMWDPLLSDAEHTGELRVVASGEGRVNNHQFYLSRRD
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCEEEEEHHH
YLAQHGDIMRRLLTELTHTGQFIDSHRGEAARLLSAELGIDARSLSIALARRSHRPRPMD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
LSVIRAQQTIADRFYALGLIAKPVPVREAVWYGEPAPDVIRPLMAVS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]