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The map label for this gene is abgR [H]

Identifier: 238896203

GI number: 238896203

Start: 4175348

End: 4176235

Strand: Reverse

Name: abgR [H]

Synonym: KP1_4352

Alternate gene names: 238896203

Gene position: 4176235-4175348 (Counterclockwise)

Preceding gene: 238896206

Following gene: 238896202

Centisome position: 79.57

GC content: 57.09

Gene sequence:

>888_bases
ATGCCAATGAAATTTAAGCAGATTCAGGCATTTATTACCGTCGCCCGCGAAGGCAATATGACCCTGGCCGCAGAGAAAAT
GGGGATCACCCAGTCGGGACTGAGCCGACTGCTATTGAGCCTGGAAGCGGACCTGAGCGCATCCTTATTCGAACGACATA
AGCACGGCATGGCGTTGAGCGAATATGGCAGCGCCTTTTTACCCTACGCGCTGACGATGCTGAATACCGAACAAAAGGCG
CGCGAGGAAATTGAGCTCATCCGCGGCGCCGGGAAAGGCATTCTGCGGATTGGCTGCGTTTCCAGTCTGCTGACCAGCCA
TTTCATCGATAAGCTGGCGGCTTTCCATCAGCGCCACCCCCAGATCCATCTGCGGATCGTCGACCGCATTGACTCCGAGC
TATATAAGCTGTTGCTGATGCACGACATCGATATCGCCCTCTGCGGCCCCTTACCGCATGATGAGAAAATCGTGGTGCGG
GGCAAAATTAACTGGCAGGACCGGATCTGCATCGTCGCCAGGCAGCACCACCCGCTGCATCAGGCGGCGGACGTCACCCT
GGAGGCGATGCTGGACTATCCGTGGATTATGCCGCCGCCGTCTAGTACGCCAATGAACATCCTGGCGGATATCTTTCGCG
CCCGGCAGTTGCCCTGTCCGCAGCCGGTTATTGAGTGCGCCTCATCCTCAGCCATTAAGGCCTTTCTGTGCGAGAGCGAT
CTGTTAACGTCGATGCCGGCCCCGGTTTACCGACACGAAGAAGCGCTTGGCCTGCTGCGCCCGTTTGAGCTCGAGGGCAG
CGTTTTTATCCGGGATTTCTATGCCTACAGCCATTTCGGGGTTCTGTCCGGGGCAGCCCTGCAGTTGATTCAGCATCTGA
AGCAGTGA

Upstream 100 bases:

>100_bases
ATGCGTTCCGGTGATTTTTGAGCGTATTGATAGCGATATTTATTCGCTAAAAAAGGGCGCAGGGGAAATGCAAAAACCGT
TTATTCAATGAGTAAATATC

Downstream 100 bases:

>100_bases
GTCTGGTCGGGTATGGATATTAAGGTGTATGATAAATGCATCTTAAAAAAGACGAAAGGCGGGGAGATGGGGAAGCGTAT
CGAACGGGAAAAAATGACGA

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPMKFKQIQAFITVAREGNMTLAAEKMGITQSGLSRLLLSLEADLSASLFERHKHGMALSEYGSAFLPYALTMLNTEQKA
REEIELIRGAGKGILRIGCVSSLLTSHFIDKLAAFHQRHPQIHLRIVDRIDSELYKLLLMHDIDIALCGPLPHDEKIVVR
GKINWQDRICIVARQHHPLHQAADVTLEAMLDYPWIMPPPSSTPMNILADIFRARQLPCPQPVIECASSSAIKAFLCESD
LLTSMPAPVYRHEEALGLLRPFELEGSVFIRDFYAYSHFGVLSGAALQLIQHLKQ

Sequences:

>Translated_295_residues
MPMKFKQIQAFITVAREGNMTLAAEKMGITQSGLSRLLLSLEADLSASLFERHKHGMALSEYGSAFLPYALTMLNTEQKA
REEIELIRGAGKGILRIGCVSSLLTSHFIDKLAAFHQRHPQIHLRIVDRIDSELYKLLLMHDIDIALCGPLPHDEKIVVR
GKINWQDRICIVARQHHPLHQAADVTLEAMLDYPWIMPPPSSTPMNILADIFRARQLPCPQPVIECASSSAIKAFLCESD
LLTSMPAPVYRHEEALGLLRPFELEGSVFIRDFYAYSHFGVLSGAALQLIQHLKQ
>Mature_294_residues
PMKFKQIQAFITVAREGNMTLAAEKMGITQSGLSRLLLSLEADLSASLFERHKHGMALSEYGSAFLPYALTMLNTEQKAR
EEIELIRGAGKGILRIGCVSSLLTSHFIDKLAAFHQRHPQIHLRIVDRIDSELYKLLLMHDIDIALCGPLPHDEKIVVRG
KINWQDRICIVARQHHPLHQAADVTLEAMLDYPWIMPPPSSTPMNILADIFRARQLPCPQPVIECASSSAIKAFLCESDL
LTSMPAPVYRHEEALGLLRPFELEGSVFIRDFYAYSHFGVLSGAALQLIQHLKQ

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=251, Percent_Identity=29.8804780876494, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081904, Length=255, Percent_Identity=23.921568627451, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI157672245, Length=256, Percent_Identity=26.5625, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788296, Length=238, Percent_Identity=26.0504201680672, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788481, Length=234, Percent_Identity=26.4957264957265, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=169, Percent_Identity=25.4437869822485, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=202, Percent_Identity=21.7821782178218, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789440, Length=126, Percent_Identity=26.984126984127, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33113; Mature: 32982

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKFKQIQAFITVAREGNMTLAAEKMGITQSGLSRLLLSLEADLSASLFERHKHGMALS
CCCHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
EYGSAFLPYALTMLNTEQKAREEIELIRGAGKGILRIGCVSSLLTSHFIDKLAAFHQRHP
HHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
QIHLRIVDRIDSELYKLLLMHDIDIALCGPLPHDEKIVVRGKINWQDRICIVARQHHPLH
EEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCHH
QAADVTLEAMLDYPWIMPPPSSTPMNILADIFRARQLPCPQPVIECASSSAIKAFLCESD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHH
LLTSMPAPVYRHEEALGLLRPFELEGSVFIRDFYAYSHFGVLSGAALQLIQHLKQ
HHHCCCCCHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMKFKQIQAFITVAREGNMTLAAEKMGITQSGLSRLLLSLEADLSASLFERHKHGMALS
CCHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
EYGSAFLPYALTMLNTEQKAREEIELIRGAGKGILRIGCVSSLLTSHFIDKLAAFHQRHP
HHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
QIHLRIVDRIDSELYKLLLMHDIDIALCGPLPHDEKIVVRGKINWQDRICIVARQHHPLH
EEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCHH
QAADVTLEAMLDYPWIMPPPSSTPMNILADIFRARQLPCPQPVIECASSSAIKAFLCESD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHH
LLTSMPAPVYRHEEALGLLRPFELEGSVFIRDFYAYSHFGVLSGAALQLIQHLKQ
HHHCCCCCHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]