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The map label for this gene is yafC [C]

Identifier: 238896115

GI number: 238896115

Start: 4090084

End: 4091016

Strand: Reverse

Name: yafC [C]

Synonym: KP1_4254

Alternate gene names: 238896115

Gene position: 4091016-4090084 (Counterclockwise)

Preceding gene: 238896119

Following gene: 238896113

Centisome position: 77.95

GC content: 64.84

Gene sequence:

>933_bases
TTGTATCCCGTAAGGAACCAATCTGTGCGCGACGATCTGAATGCGATCCCGGTATTTGTCACCGTGGTCGAGAGCGGCAA
CTTTGCCAGCGCGGCGGCGATCCTCCATGTGACGCGTTCGGCGGTGGGAAAAACCATTGCCCGGCTGGAAGCGCGTCTCG
GCGTGGCGTTATTCCAGCGTACCACCCGACGGCAACTGCTGACGGAAGAGGGGGAGCAATTTTATCTCCAGTGCCGGGAA
GCGCTGGAGCGCATCCGCGAGGCCGAAGAGACGCTGCAGCGCGGCAAAGATGAGGTGCAGGGGCGGCTGCGGGTGTCGCT
GCCGGTGCTGTTTGGCCAGCGCTGCGTGGCACCGCTGCTGTTCCGCCTCAGCCAGCGCTATCCGTTACTGAAGCTCGAGC
TCCACTACAGCGACCGGCAGGTCAATCTGCTGGAGGAGGGGTTTGATCTTGCGGTGCGTATCGGGAGCCTGGCCGATACC
GGGTCGCTGCGGGCCCGGGCGCTGGGAGAGCACGGCATGGTGCTGTGCGCGGCGGCGGAGTACCTGCGCCAGCAGCCAGC
GCCGCAGACTATTGCCGGGTTGAACGAGCACCGTACCCTCGGCTATCTGCACAACGGCCAGCTGCAAAAATGGCAACTGT
ATGACCCGCAGCAGGGCGAAGTGCGCTTCAGTCCGCAGACATGGCTGATACAGGATGATTTTGCCGCCATCGCGGCGGCA
GTGCAGCAGGGGATGGGCATCGCCTGGCTGCCGGACTGGCTGGTGGCGCAGGCGCTTGCCGATGGGACATTGCAGCAGGT
GTTGGCGCCCAGCGCTCAGGTGCGTTTCGCCATCCACGCGGTATGGCCGGAGGGGCCGTGGCTGCCGCAAAAAACGCGGG
CGGCGATCGATGCCCTGCGGGGAGGGCTGCCTCTTACCGCAACACCTGGTTAG

Upstream 100 bases:

>100_bases
TAAAACCAGAACGTTAGCCATGATGAGTGCCTCAAATGAAAGATAGAAGCAAAGACTAACACTGTCTTTTTTGTCTCAGG
AGTGACATTATTTTTCCCTA

Downstream 100 bases:

>100_bases
CGCAGAGAGAAATAACCGCCATCTATGGCGGCGGAGGTTTTCCGACAGCGTGCAAGCTACCGGCGCGCTTTACGCCGTAG
CCTCAGCGACGAGGCCGTCC

Product: putative LysR-family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MYPVRNQSVRDDLNAIPVFVTVVESGNFASAAAILHVTRSAVGKTIARLEARLGVALFQRTTRRQLLTEEGEQFYLQCRE
ALERIREAEETLQRGKDEVQGRLRVSLPVLFGQRCVAPLLFRLSQRYPLLKLELHYSDRQVNLLEEGFDLAVRIGSLADT
GSLRARALGEHGMVLCAAAEYLRQQPAPQTIAGLNEHRTLGYLHNGQLQKWQLYDPQQGEVRFSPQTWLIQDDFAAIAAA
VQQGMGIAWLPDWLVAQALADGTLQQVLAPSAQVRFAIHAVWPEGPWLPQKTRAAIDALRGGLPLTATPG

Sequences:

>Translated_310_residues
MYPVRNQSVRDDLNAIPVFVTVVESGNFASAAAILHVTRSAVGKTIARLEARLGVALFQRTTRRQLLTEEGEQFYLQCRE
ALERIREAEETLQRGKDEVQGRLRVSLPVLFGQRCVAPLLFRLSQRYPLLKLELHYSDRQVNLLEEGFDLAVRIGSLADT
GSLRARALGEHGMVLCAAAEYLRQQPAPQTIAGLNEHRTLGYLHNGQLQKWQLYDPQQGEVRFSPQTWLIQDDFAAIAAA
VQQGMGIAWLPDWLVAQALADGTLQQVLAPSAQVRFAIHAVWPEGPWLPQKTRAAIDALRGGLPLTATPG
>Mature_310_residues
MYPVRNQSVRDDLNAIPVFVTVVESGNFASAAAILHVTRSAVGKTIARLEARLGVALFQRTTRRQLLTEEGEQFYLQCRE
ALERIREAEETLQRGKDEVQGRLRVSLPVLFGQRCVAPLLFRLSQRYPLLKLELHYSDRQVNLLEEGFDLAVRIGSLADT
GSLRARALGEHGMVLCAAAEYLRQQPAPQTIAGLNEHRTLGYLHNGQLQKWQLYDPQQGEVRFSPQTWLIQDDFAAIAAA
VQQGMGIAWLPDWLVAQALADGTLQQVLAPSAQVRFAIHAVWPEGPWLPQKTRAAIDALRGGLPLTATPG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=32.404181184669, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=31.0104529616725, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI145693193, Length=275, Percent_Identity=29.8181818181818, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=30.6338028169014, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87081978, Length=258, Percent_Identity=34.4961240310078, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=26.5993265993266, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787589, Length=261, Percent_Identity=26.4367816091954, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789173, Length=246, Percent_Identity=31.3008130081301, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786713, Length=283, Percent_Identity=29.6819787985866, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788706, Length=273, Percent_Identity=26.3736263736264, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082132, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=33.6134453781513, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788481, Length=272, Percent_Identity=25.3676470588235, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786448, Length=302, Percent_Identity=27.4834437086093, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34445; Mature: 34445

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPVRNQSVRDDLNAIPVFVTVVESGNFASAAAILHVTRSAVGKTIARLEARLGVALFQR
CCCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTRRQLLTEEGEQFYLQCREALERIREAEETLQRGKDEVQGRLRVSLPVLFGQRCVAPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHHHHH
FRLSQRYPLLKLELHYSDRQVNLLEEGFDLAVRIGSLADTGSLRARALGEHGMVLCAAAE
HHHHCCCCEEEEEEECCCCCHHHHHCCCEEEEEECCCCCCCCHHHHHCCCCCEEHHHHHH
YLRQQPAPQTIAGLNEHRTLGYLHNGQLQKWQLYDPQQGEVRFSPQTWLIQDDFAAIAAA
HHHHCCCCHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCEEEEEHHHHHHHHH
VQQGMGIAWLPDWLVAQALADGTLQQVLAPSAQVRFAIHAVWPEGPWLPQKTRAAIDALR
HHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHH
GGLPLTATPG
CCCCCCCCCC
>Mature Secondary Structure
MYPVRNQSVRDDLNAIPVFVTVVESGNFASAAAILHVTRSAVGKTIARLEARLGVALFQR
CCCCCCCCHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTRRQLLTEEGEQFYLQCREALERIREAEETLQRGKDEVQGRLRVSLPVLFGQRCVAPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHHHHHH
FRLSQRYPLLKLELHYSDRQVNLLEEGFDLAVRIGSLADTGSLRARALGEHGMVLCAAAE
HHHHCCCCEEEEEEECCCCCHHHHHCCCEEEEEECCCCCCCCHHHHHCCCCCEEHHHHHH
YLRQQPAPQTIAGLNEHRTLGYLHNGQLQKWQLYDPQQGEVRFSPQTWLIQDDFAAIAAA
HHHHCCCCHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCEEEEEHHHHHHHHH
VQQGMGIAWLPDWLVAQALADGTLQQVLAPSAQVRFAIHAVWPEGPWLPQKTRAAIDALR
HHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHH
GGLPLTATPG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]