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The map label for this gene is gbh [H]

Identifier: 238896094

GI number: 238896094

Start: 4065134

End: 4066135

Strand: Direct

Name: gbh [H]

Synonym: KP1_4232

Alternate gene names: 238896094

Gene position: 4065134-4066135 (Clockwise)

Preceding gene: 238896092

Following gene: 238896095

Centisome position: 77.45

GC content: 60.88

Gene sequence:

>1002_bases
TTGCGCACTATCTCTCCTGTTACGTTTCATCCGTCAGATTCAGGAGCAGACATGGATAACCTCTTTCACCAACCGCAGGG
TGGCAATGAGATGCCACGCTTCGCCGGACGCGCCACAATGATGCGCCTGCCGTTTATCGAAAATTTACAGGGACTTGACG
CGGCATTTGTCGGCATTCCGCTGGATATCGGCACCTCGCAGCGCTCGGGCACGCGCTACGGACCACGCTATATTCGCGCC
GAATCGGTGATGATCCGTCCGTACAATATGGCGACCGGCGCCGCGCCGTTCGACTCGCTGTCGGTGGCTGATATCGGCGA
TGTGCCGATCAATACCTACAGCCTGCTCAAATCGGTGCAAATTATCGAAGATTACTACACCGGTTTGAATAGTTATCCGC
TGATCCCGCTGACCCTCGGCGGGGACCACACCATTACCCTGCCGATCCTGCGGGCGCTGACCAAAAAACATGGTCCGGTG
GGCCTCATCCACGTCGACGCCCATACCGACACCAATGATGAGATGTTCGGAGAGAAAATCGCCCACGGCACCACCTTCCG
CCGCGCCGTTGAGGAGGGACTGCTCGACCTCAAACGGGTGGTGCAGATTGGCCAGCGCGCCCAGGGCTATGCCGCCGGCG
ACTTCCAGTGGGGCGTTGACCAGGGCTTTCGCCTGGTGCAGGCGGAGCAGTGCTGGCATACCTCGCTGGCGCCGCTGATG
GCCGAAGTCCGCCAGCAGATGGGCGACGGGCCGGTGTATCTCAGCTTTGATATCGATAGCCTCGATCCCATCTGGGCTCC
AGGAACCGGGACGCCGGAAGTTGGCGGTCTGACCTCCATTCAGGCGCTGGAGATCGTCCGCGGCTGCCGCGGCCTGAATC
TGATTGGCGCCGATCTGGTCGAGGTCTCGCCCCCCTACGACGTGAGCGGTAATACCTCCCAGCTGGCGGCCAACCTGCTG
TACGAGATGCTCTGCGTCCTGCCCGGCGTGAAGTACGCCTGA

Upstream 100 bases:

>100_bases
CAGCTGGCGAATATTGAGGCTGGCGTCGTGATGCATCGTATTTAGTTCACCAATAAATGAACTGAGTATTTACGCCAGAC
GATGTAAAGTCCAGCGCGGG

Downstream 100 bases:

>100_bases
GGAAGCCGCCATGGAGCTGAAATGCTTTCGCACCCTCTGGGGAGTGACGACCCCCTGGCCGCAAACGCTGGATGAACTGC
AGCGTGTCGGCTGCTGCGGT

Product: putative arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRTISPVTFHPSDSGADMDNLFHQPQGGNEMPRFAGRATMMRLPFIENLQGLDAAFVGIPLDIGTSQRSGTRYGPRYIRA
ESVMIRPYNMATGAAPFDSLSVADIGDVPINTYSLLKSVQIIEDYYTGLNSYPLIPLTLGGDHTITLPILRALTKKHGPV
GLIHVDAHTDTNDEMFGEKIAHGTTFRRAVEEGLLDLKRVVQIGQRAQGYAAGDFQWGVDQGFRLVQAEQCWHTSLAPLM
AEVRQQMGDGPVYLSFDIDSLDPIWAPGTGTPEVGGLTSIQALEIVRGCRGLNLIGADLVEVSPPYDVSGNTSQLAANLL
YEMLCVLPGVKYA

Sequences:

>Translated_333_residues
MRTISPVTFHPSDSGADMDNLFHQPQGGNEMPRFAGRATMMRLPFIENLQGLDAAFVGIPLDIGTSQRSGTRYGPRYIRA
ESVMIRPYNMATGAAPFDSLSVADIGDVPINTYSLLKSVQIIEDYYTGLNSYPLIPLTLGGDHTITLPILRALTKKHGPV
GLIHVDAHTDTNDEMFGEKIAHGTTFRRAVEEGLLDLKRVVQIGQRAQGYAAGDFQWGVDQGFRLVQAEQCWHTSLAPLM
AEVRQQMGDGPVYLSFDIDSLDPIWAPGTGTPEVGGLTSIQALEIVRGCRGLNLIGADLVEVSPPYDVSGNTSQLAANLL
YEMLCVLPGVKYA
>Mature_333_residues
MRTISPVTFHPSDSGADMDNLFHQPQGGNEMPRFAGRATMMRLPFIENLQGLDAAFVGIPLDIGTSQRSGTRYGPRYIRA
ESVMIRPYNMATGAAPFDSLSVADIGDVPINTYSLLKSVQIIEDYYTGLNSYPLIPLTLGGDHTITLPILRALTKKHGPV
GLIHVDAHTDTNDEMFGEKIAHGTTFRRAVEEGLLDLKRVVQIGQRAQGYAAGDFQWGVDQGFRLVQAEQCWHTSLAPLM
AEVRQQMGDGPVYLSFDIDSLDPIWAPGTGTPEVGGLTSIQALEIVRGCRGLNLIGADLVEVSPPYDVSGNTSQLAANLL
YEMLCVLPGVKYA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=324, Percent_Identity=60.1851851851852, Blast_Score=393, Evalue=1e-109,
Organism=Escherichia coli, GI1789306, Length=302, Percent_Identity=39.7350993377483, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6325146, Length=194, Percent_Identity=31.4432989690722, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 36192; Mature: 36192

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTISPVTFHPSDSGADMDNLFHQPQGGNEMPRFAGRATMMRLPFIENLQGLDAAFVGIP
CCCCCCCEECCCCCCCCHHHHHCCCCCCCCCCHHHCCHHEEECCHHHCCCCCCEEEEEEE
LDIGTSQRSGTRYGPRYIRAESVMIRPYNMATGAAPFDSLSVADIGDVPINTYSLLKSVQ
EECCCCCCCCCCCCCEEEEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
IIEDYYTGLNSYPLIPLTLGGDHTITLPILRALTKKHGPVGLIHVDAHTDTNDEMFGEKI
HHHHHHCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
AHGTTFRRAVEEGLLDLKRVVQIGQRAQGYAAGDFQWGVDQGFRLVQAEQCWHTSLAPLM
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
AEVRQQMGDGPVYLSFDIDSLDPIWAPGTGTPEVGGLTSIQALEIVRGCRGLNLIGADLV
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCHHE
EVSPPYDVSGNTSQLAANLLYEMLCVLPGVKYA
ECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTISPVTFHPSDSGADMDNLFHQPQGGNEMPRFAGRATMMRLPFIENLQGLDAAFVGIP
CCCCCCCEECCCCCCCCHHHHHCCCCCCCCCCHHHCCHHEEECCHHHCCCCCCEEEEEEE
LDIGTSQRSGTRYGPRYIRAESVMIRPYNMATGAAPFDSLSVADIGDVPINTYSLLKSVQ
EECCCCCCCCCCCCCEEEEECEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
IIEDYYTGLNSYPLIPLTLGGDHTITLPILRALTKKHGPVGLIHVDAHTDTNDEMFGEKI
HHHHHHCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
AHGTTFRRAVEEGLLDLKRVVQIGQRAQGYAAGDFQWGVDQGFRLVQAEQCWHTSLAPLM
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
AEVRQQMGDGPVYLSFDIDSLDPIWAPGTGTPEVGGLTSIQALEIVRGCRGLNLIGADLV
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCHHE
EVSPPYDVSGNTSQLAANLLYEMLCVLPGVKYA
ECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA