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The map label for this gene is yfhH [H]

Identifier: 238896012

GI number: 238896012

Start: 3975375

End: 3976223

Strand: Direct

Name: yfhH [H]

Synonym: KP1_4140

Alternate gene names: 238896012

Gene position: 3975375-3976223 (Clockwise)

Preceding gene: 238896009

Following gene: 238896013

Centisome position: 75.74

GC content: 60.54

Gene sequence:

>849_bases
ATGAACTGTTTAACGCGTATTCGTCAGCGCTATCCCACCCTGGCGGCGAGCGACAAAAAGTTGGCCGATTATATTCTAAG
CCAGCCCGATGAGACCCGGCACCTCAGCTCGCAGCAGCTGGCAGCGGAAGCCGGTGTGAGTCAGTCCAGCGTGGTTAAGT
TTGCCCAGAAGCTGGGATTCAAAGGCTTTCCGGCGCTGAAGCTGGCCCTTAGTGAAGCGCTGGCGAGTAGCCCGGATCCG
CACTCCGTCCCGGTGCATAACCACATTCGCGGTGACGATCCGCTGCGTCTGGTCGGCGAGAAACTCATTAAAGACAATGT
CGCCGCCATGCATGCCTCGCTGGACGTCAACACTGAAGAGACGCTACGGGAAGCCGTCACGCTGCTGCGCAACGCCCGGC
GAGTGATCGTCACCGGGATTGGCGCCTCCGGCCTGGTGGCGCGTAACTTTAGCTGGAAGCTGATGAAGATCGGCATCAAC
GCTGTTTCTGAGCAGGATATGCATGCCCTGCTGGCGACGGTGCAGGCCATGTCCAGCGACGATCTTCTGCTGGCGATCTC
TTACTCCGGCGAGCGCCGGGAGATCAATATGGCGGCCGGTGAAGCGCTGCGCGTCGGCTGTAAGATCCTGGCGATCACCG
GGTTTAGCCCGAACGCCCTGCAACAGCAGGCGACCCACTGCCTGTATACTATCGCCGAAGAGCAGGCGACGCGCAGCGCG
GCCATCTCCTCCACAAGCGCGCAAATGATGCTCACCGATCTGCTGTTTATGGGGCTGGTGCAGCAGGATCTGGAGCGGGC
GCCGGAGCGCATTCGCCATAGCGAAGCGCTGGTGAAAAAGCTGGTCTGA

Upstream 100 bases:

>100_bases
GGAAAAATTGTGGCTTAAGAATTTTTAATTCATGGTATACCCCTTATAATCGAATAAAAATTCTGTCAGTCACGAGCCGG
ACGGCTCCAGCGGAGCTCCA

Downstream 100 bases:

>100_bases
GCAGAAAATGGGCGTATAATGCCCGCCCTGTTTGTGTTGTTTCTGAGACTTTCCTGATGGCGCTGTTAATTACCAAAAAA
TGCATCAACTGCGATATGTG

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNCLTRIRQRYPTLAASDKKLADYILSQPDETRHLSSQQLAAEAGVSQSSVVKFAQKLGFKGFPALKLALSEALASSPDP
HSVPVHNHIRGDDPLRLVGEKLIKDNVAAMHASLDVNTEETLREAVTLLRNARRVIVTGIGASGLVARNFSWKLMKIGIN
AVSEQDMHALLATVQAMSSDDLLLAISYSGERREINMAAGEALRVGCKILAITGFSPNALQQQATHCLYTIAEEQATRSA
AISSTSAQMMLTDLLFMGLVQQDLERAPERIRHSEALVKKLV

Sequences:

>Translated_282_residues
MNCLTRIRQRYPTLAASDKKLADYILSQPDETRHLSSQQLAAEAGVSQSSVVKFAQKLGFKGFPALKLALSEALASSPDP
HSVPVHNHIRGDDPLRLVGEKLIKDNVAAMHASLDVNTEETLREAVTLLRNARRVIVTGIGASGLVARNFSWKLMKIGIN
AVSEQDMHALLATVQAMSSDDLLLAISYSGERREINMAAGEALRVGCKILAITGFSPNALQQQATHCLYTIAEEQATRSA
AISSTSAQMMLTDLLFMGLVQQDLERAPERIRHSEALVKKLV
>Mature_282_residues
MNCLTRIRQRYPTLAASDKKLADYILSQPDETRHLSSQQLAAEAGVSQSSVVKFAQKLGFKGFPALKLALSEALASSPDP
HSVPVHNHIRGDDPLRLVGEKLIKDNVAAMHASLDVNTEETLREAVTLLRNARRVIVTGIGASGLVARNFSWKLMKIGIN
AVSEQDMHALLATVQAMSSDDLLLAISYSGERREINMAAGEALRVGCKILAITGFSPNALQQQATHCLYTIAEEQATRSA
AISSTSAQMMLTDLLFMGLVQQDLERAPERIRHSEALVKKLV

Specific function: Unknown

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082130, Length=282, Percent_Identity=78.7234042553192, Blast_Score=452, Evalue=1e-129,
Organism=Escherichia coli, GI1788767, Length=284, Percent_Identity=35.5633802816901, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788159, Length=284, Percent_Identity=26.056338028169, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87082369, Length=273, Percent_Identity=21.978021978022, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30696; Mature: 30696

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCLTRIRQRYPTLAASDKKLADYILSQPDETRHLSSQQLAAEAGVSQSSVVKFAQKLGF
CCHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KGFPALKLALSEALASSPDPHSVPVHNHIRGDDPLRLVGEKLIKDNVAAMHASLDVNTEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
TLREAVTLLRNARRVIVTGIGASGLVARNFSWKLMKIGINAVSEQDMHALLATVQAMSSD
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCHHCCHHHHHHHHHHHHHCCCC
DLLLAISYSGERREINMAAGEALRVGCKILAITGFSPNALQQQATHCLYTIAEEQATRSA
CEEEEEECCCCCEEEEHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AISSTSAQMMLTDLLFMGLVQQDLERAPERIRHSEALVKKLV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNCLTRIRQRYPTLAASDKKLADYILSQPDETRHLSSQQLAAEAGVSQSSVVKFAQKLGF
CCHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KGFPALKLALSEALASSPDPHSVPVHNHIRGDDPLRLVGEKLIKDNVAAMHASLDVNTEE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
TLREAVTLLRNARRVIVTGIGASGLVARNFSWKLMKIGINAVSEQDMHALLATVQAMSSD
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCHHCCHHHHHHHHHHHHHCCCC
DLLLAISYSGERREINMAAGEALRVGCKILAITGFSPNALQQQATHCLYTIAEEQATRSA
CEEEEEECCCCCEEEEHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AISSTSAQMMLTDLLFMGLVQQDLERAPERIRHSEALVKKLV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 1602968; 7984428 [H]