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The map label for this gene is hscB [H]

Identifier: 238895984

GI number: 238895984

Start: 3943173

End: 3943688

Strand: Reverse

Name: hscB [H]

Synonym: KP1_4111

Alternate gene names: 238895984

Gene position: 3943688-3943173 (Counterclockwise)

Preceding gene: 238895985

Following gene: 238895983

Centisome position: 75.14

GC content: 55.62

Gene sequence:

>516_bases
ATGGACTATTTCACCCTCTTCGGGTTACCAGCCAGCTATACCCTCTCGCTTGAACAACTGGCTGTCCGGTATCAGGATCT
GCAGCGCCAGTACCATCCGGATAAATTTGCCAGCGCGCCTGCGGCGGAACAGCTTGCGGCGGTTCAGCATTCCGCCACTA
TAAACCAGGCCTGGCAGACGCTGCGCCATCCGCTGACTCGCGCAGAATATCTCCTTTCGCTGCATGGCTTCGATCTGGCC
AGCGAGCAGCATACCGTTCGCGATACCGCGTTCCTGATGGAACAGCTGGAATTGCGCGAAGAGCTGGATGAGATCGGCCA
GGCGAAAGACGACGCGCGGCTGGAAGGTTTTATCAAACGGGTGAAAGCGCTGTTTGATACCCGTCAGCAGCTGATGGTTG
ACCAATTGCATAATGAGAGCTGGGAGGCGGCGGCGGACACGGTTCGTAAGCTCCGTTTCCTCGATAAACTGCGCAGCAGT
GCTGAAGAACTCGAAGAAAAACTGCTCGATTTTTAA

Upstream 100 bases:

>100_bases
GCTGCGGCGAAAGCTTTAACGTATAATCGGTACTCCTCAACCCCACCGCGGTCACGCCGCGCGTGGGGTTTTAATTTAGA
TGCATGACCCTGAGGTTACT

Downstream 100 bases:

>100_bases
TTTTCGGAAGCAATTATGGCCTTATTACAAATTAGTGAGCCCGGCCTGAGCGCCGCGCCGCACCAGCGTCGTCTGGCGGC
CGGTATCGACCTGGGCACCA

Product: co-chaperone HscB

Products: NA

Alternate protein names: Hsc20 [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MDYFTLFGLPASYTLSLEQLAVRYQDLQRQYHPDKFASAPAAEQLAAVQHSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLELREELDEIGQAKDDARLEGFIKRVKALFDTRQQLMVDQLHNESWEAAADTVRKLRFLDKLRSS
AEELEEKLLDF

Sequences:

>Translated_171_residues
MDYFTLFGLPASYTLSLEQLAVRYQDLQRQYHPDKFASAPAAEQLAAVQHSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLELREELDEIGQAKDDARLEGFIKRVKALFDTRQQLMVDQLHNESWEAAADTVRKLRFLDKLRSS
AEELEEKLLDF
>Mature_171_residues
MDYFTLFGLPASYTLSLEQLAVRYQDLQRQYHPDKFASAPAAEQLAAVQHSATINQAWQTLRHPLTRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLELREELDEIGQAKDDARLEGFIKRVKALFDTRQQLMVDQLHNESWEAAADTVRKLRFLDKLRSS
AEELEEKLLDF

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=160, Percent_Identity=30.625, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1788876, Length=171, Percent_Identity=85.3801169590643, Blast_Score=295, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17541320, Length=145, Percent_Identity=28.9655172413793, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161084223, Length=180, Percent_Identity=25.5555555555556, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19825; Mature: 19825

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFTLFGLPASYTLSLEQLAVRYQDLQRQYHPDKFASAPAAEQLAAVQHSATINQAWQT
CCCHHEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
LRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIGQAKDDARLEGFIKR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VKALFDTRQQLMVDQLHNESWEAAADTVRKLRFLDKLRSSAEELEEKLLDF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDYFTLFGLPASYTLSLEQLAVRYQDLQRQYHPDKFASAPAAEQLAAVQHSATINQAWQT
CCCHHEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
LRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIGQAKDDARLEGFIKR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VKALFDTRQQLMVDQLHNESWEAAADTVRKLRFLDKLRSSAEELEEKLLDF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA