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The map label for this gene is ptsJ [H]

Identifier: 238895892

GI number: 238895892

Start: 3839802

End: 3841100

Strand: Direct

Name: ptsJ [H]

Synonym: KP1_4015

Alternate gene names: 238895892

Gene position: 3839802-3841100 (Clockwise)

Preceding gene: 238895889

Following gene: 238895893

Centisome position: 73.16

GC content: 64.59

Gene sequence:

>1299_bases
ATGTTAGCCGGAAAAACCGCCAGCGAAATCTTCGATAATATCCGCCATCTGGTGCAGAGCGGCGGGTTGCAGCCCGGAGA
GGTTCTGCCGCCGGTACGTGAACTCGCCAGCCAGCTTGCAGTGAATCGCAACACTGTCGCCGCCGCCTATAAACGGCTGG
TGACCTCCGGGCTGGCCGTCAGTCAGGGACGCAACGGTACAGCCATTAAAGCGCGGGACACACTGCCGGCGCTGGAGGGA
GGTGACCCAACGACCCCGCTGAACGATATCTCCAGCGGCAATCCGGATCCAGCCAGACTGCCTGATTTACCCCGCTATCT
GGGCCAGATTGCCCGCACGCCCCGCCTGTATGGCGATGCGCCCATTGAGCCGCGGCTTGGCCAATGGGCCGAGGCGTGGT
TTGCCAGAGAGATAGCCGTTCCCTTTGCGGTGAATCTCGCCAGCGGGGCGATAGACGCCCTGGAGCGCCTGCTGTGCGCC
CTGCTGCTCCCCGGCGACGGCGTTGTGGTGGAAGATCCCTGTTTTCTCAGCAGCATCAATATGGTGCGTTACGCCGGTTT
TACCCCCTGCCCGGTGGCGGTGGATGCCGAAGGGATGGATCCTGACGGCCTGGAGGAGGCGTTACGCAACGGCGCACGGG
CGGTGATCTTAACCCCGCGCGCGCATAATCCTACCGGCTGTAGCCTGACGGAAACCCGGGCGCATGCCCTGCGGGAGGTG
CTAGCCCGCTATCCGCAGGTACTGGCGATTGTTGATGACCATTTTGCCCTGCTGTCGGCCACGCCATGGCACTCCCCTCT
TCCTGCAAGCACCCAACGCTGGGCGCTGGTGCGCTCAATGTCAAAAACCCTCGGACCAGACCTGCGGCTGGCCTTTATCG
CCAGCGATGCCGCTACTTCAGCGGCGCTGCGCCTGCGGCTTAACGCCGGCAGCCAGTGGGTCAGCCATCTGCTGCAGGAC
CTGACGCTGGCCTGCCTGACCGACGAGGCGTTTATCGCCTCGATGACGGAGACTCGTCGTCACTATCGCCAGCAGAATGA
GAAACTGGCGGCGGCGCTGGCCCGGCACGGCTTCAGCCATGCTACGCCAGGGGATGGCCTCAATTTCTGGCTGCCGCTGC
CAGCGGCGAGCCAGCCCTACGCCTTACGCCTGGCCCGCGCCGGCTGGCTGGTCCGGGAGGGAGAGGTGTTTGGCATCCGT
ACGCCCTCCCACGGGCTACGCCTGTCGCTGGGCCGTCTGAGTGACGCTGAGATTTCCCGCCTGGCGGCCGATATTGCGCA
GGCCTTAGACGCCCCCTGA

Upstream 100 bases:

>100_bases
ATCATCCTGCTGGCCCATCTTTTCTCCCCCCGCTGGACAGCGGGTCACGCACTGATTATGATTCGTCCTATGCTAAATTC
CATTTTGTCATAGGTCAATA

Downstream 100 bases:

>100_bases
CGCAGGCAGTCCACCGAACGTATCGGGGAGTGATGGCAGCTGCCGACAAATTAATGAAAAATAAACGACAGCAGGCTAGT
CTTACCTGCATGCCCTGATC

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLAGKTASEIFDNIRHLVQSGGLQPGEVLPPVRELASQLAVNRNTVAAAYKRLVTSGLAVSQGRNGTAIKARDTLPALEG
GDPTTPLNDISSGNPDPARLPDLPRYLGQIARTPRLYGDAPIEPRLGQWAEAWFAREIAVPFAVNLASGAIDALERLLCA
LLLPGDGVVVEDPCFLSSINMVRYAGFTPCPVAVDAEGMDPDGLEEALRNGARAVILTPRAHNPTGCSLTETRAHALREV
LARYPQVLAIVDDHFALLSATPWHSPLPASTQRWALVRSMSKTLGPDLRLAFIASDAATSAALRLRLNAGSQWVSHLLQD
LTLACLTDEAFIASMTETRRHYRQQNEKLAAALARHGFSHATPGDGLNFWLPLPAASQPYALRLARAGWLVREGEVFGIR
TPSHGLRLSLGRLSDAEISRLAADIAQALDAP

Sequences:

>Translated_432_residues
MLAGKTASEIFDNIRHLVQSGGLQPGEVLPPVRELASQLAVNRNTVAAAYKRLVTSGLAVSQGRNGTAIKARDTLPALEG
GDPTTPLNDISSGNPDPARLPDLPRYLGQIARTPRLYGDAPIEPRLGQWAEAWFAREIAVPFAVNLASGAIDALERLLCA
LLLPGDGVVVEDPCFLSSINMVRYAGFTPCPVAVDAEGMDPDGLEEALRNGARAVILTPRAHNPTGCSLTETRAHALREV
LARYPQVLAIVDDHFALLSATPWHSPLPASTQRWALVRSMSKTLGPDLRLAFIASDAATSAALRLRLNAGSQWVSHLLQD
LTLACLTDEAFIASMTETRRHYRQQNEKLAAALARHGFSHATPGDGLNFWLPLPAASQPYALRLARAGWLVREGEVFGIR
TPSHGLRLSLGRLSDAEISRLAADIAQALDAP
>Mature_432_residues
MLAGKTASEIFDNIRHLVQSGGLQPGEVLPPVRELASQLAVNRNTVAAAYKRLVTSGLAVSQGRNGTAIKARDTLPALEG
GDPTTPLNDISSGNPDPARLPDLPRYLGQIARTPRLYGDAPIEPRLGQWAEAWFAREIAVPFAVNLASGAIDALERLLCA
LLLPGDGVVVEDPCFLSSINMVRYAGFTPCPVAVDAEGMDPDGLEEALRNGARAVILTPRAHNPTGCSLTETRAHALREV
LARYPQVLAIVDDHFALLSATPWHSPLPASTQRWALVRSMSKTLGPDLRLAFIASDAATSAALRLRLNAGSQWVSHLLQD
LTLACLTDEAFIASMTETRRHYRQQNEKLAAALARHGFSHATPGDGLNFWLPLPAASQPYALRLARAGWLVREGEVFGIR
TPSHGLRLSLGRLSDAEISRLAADIAQALDAP

Specific function: Putative transcriptional regulator of the ptsHI/crr operon [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=23.8853503184713, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=23.8853503184713, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787710, Length=412, Percent_Identity=26.4563106796117, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790797, Length=426, Percent_Identity=23.7089201877934, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 46378; Mature: 46378

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGKTASEIFDNIRHLVQSGGLQPGEVLPPVRELASQLAVNRNTVAAAYKRLVTSGLAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
SQGRNGTAIKARDTLPALEGGDPTTPLNDISSGNPDPARLPDLPRYLGQIARTPRLYGDA
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PIEPRLGQWAEAWFAREIAVPFAVNLASGAIDALERLLCALLLPGDGVVVEDPCFLSSIN
CCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCC
MVRYAGFTPCPVAVDAEGMDPDGLEEALRNGARAVILTPRAHNPTGCSLTETRAHALREV
HHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
LARYPQVLAIVDDHFALLSATPWHSPLPASTQRWALVRSMSKTLGPDLRLAFIASDAATS
HHHCCCEEEHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCHHCC
AALRLRLNAGSQWVSHLLQDLTLACLTDEAFIASMTETRRHYRQQNEKLAAALARHGFSH
EEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ATPGDGLNFWLPLPAASQPYALRLARAGWLVREGEVFGIRTPSHGLRLSLGRLSDAEISR
CCCCCCCEEEEECCCCCCCHHEEEHHCCCEEECCCEEEEECCCCCCEEEECCCCHHHHHH
LAADIAQALDAP
HHHHHHHHHCCC
>Mature Secondary Structure
MLAGKTASEIFDNIRHLVQSGGLQPGEVLPPVRELASQLAVNRNTVAAAYKRLVTSGLAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
SQGRNGTAIKARDTLPALEGGDPTTPLNDISSGNPDPARLPDLPRYLGQIARTPRLYGDA
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PIEPRLGQWAEAWFAREIAVPFAVNLASGAIDALERLLCALLLPGDGVVVEDPCFLSSIN
CCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHCC
MVRYAGFTPCPVAVDAEGMDPDGLEEALRNGARAVILTPRAHNPTGCSLTETRAHALREV
HHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
LARYPQVLAIVDDHFALLSATPWHSPLPASTQRWALVRSMSKTLGPDLRLAFIASDAATS
HHHCCCEEEHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCHHCC
AALRLRLNAGSQWVSHLLQDLTLACLTDEAFIASMTETRRHYRQQNEKLAAALARHGFSH
EEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ATPGDGLNFWLPLPAASQPYALRLARAGWLVREGEVFGIRTPSHGLRLSLGRLSDAEISR
CCCCCCCEEEEECCCCCCCHHEEEHHCCCEEECCCEEEEECCCCCCEEEECCCCHHHHHH
LAADIAQALDAP
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7612925; 11677609 [H]