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The map label for this gene is cynX [H]

Identifier: 238895864

GI number: 238895864

Start: 3807728

End: 3808924

Strand: Direct

Name: cynX [H]

Synonym: KP1_3984

Alternate gene names: 238895864

Gene position: 3807728-3808924 (Clockwise)

Preceding gene: 238895863

Following gene: 238895866

Centisome position: 72.55

GC content: 64.83

Gene sequence:

>1197_bases
ATGACACCAGCGCTGCGACAGAACCTGACGCTGGCAGTCCTGGTACTGACTGGGATCAATATGCGGCCGCTGCTTACCTC
CATTGGTCCTTTGCTGCCGGACATCCGCGCAGCCAGCGGCATGAGCTATACCCTGGCCGCACTCCTGACCGCGCTGCCGG
TGATCGCGATGGGGGTGCTGGCGCTGGCCGCTGGCTGGGTCGATCGCTATATCGGTCAAAAGCGCAGTATTGCGCTGAGC
CTGCTGATTATCGCGGCAGGCGCCCTGCTGCGGGAAATCGCCCCGAATAGTGGCTTACTGCTCACCAGCGCTCTGGCCGG
AGGAATTGGCATCGGCATTATTCAGGCCGCCATCCCGGCGGTAATTAAGCACCTCTTTCCCCGACGGACGCCGCTGGTGA
TGGGACTATGGTCAGCGGCGCTGATGGGCGGCGGCGGGTTAGGCGCCGCGTTCACCCCATGGCTGGCGTCACATAGCGCG
GCCTGGCATGATGCGCTAGCCTGGTGGGCGCTCCCTGCGCTCCTGGCTCTGTTCAGCTGGCTGGCGATTTGTCGGCAATT
GCCTCGCGCACCGCATCAGGCCAGCGCTTCCCCCCGGGTCGCGATTATTGGCCAGCGCCGCGCCTGGACGCTGGGACTCT
ATTTCGGACTGATCAATGCCGGTTACGCCAGCCTGATCGCCTGGCTGCCTCCTTACTACATCCAGCTAGGCGACAGCGCC
CAGTACAGTGGTTCGCTGCTGGCGCTGCTGACCGTCGGGCAAACCGCCGGCGCGCTGCTGCTCCCGGCGCTGGCTCGCCA
GGAGGATCGGCGCCAGCTTCTTCTGCTAGCGCTGGCGCTACAGCTGATTGGCTTCTGCGGCTTTATCTGGCTGCCAGAGC
ATTTCTCTGCGCTCTGGGCCATTGCCTGCGGCGTGGGGTTGGGCGGCGCGTTTCCTCTGTGCCTGGTGCTGGCGCTGGAT
CACGCCGGACAACCGGCGGTGGCCGGCAGGCTGGTAGCCTTTATGCAGGGGATCGGATTTATCATCGCCGGTCTGTCGCC
CTGGCTTTCCGGCCTGCTGCGTAGCCTGAGCGGGAACTACACGCTTGACTGGTCCTGGCATGCGATCTGCGTCCTGCTAC
TCATGGCGCTGACGCTGCGCTTTATCCCGGCACACTACCCGGCCGAGTGGCGACAGCGCGCCTCAGACCTGCCCTGA

Upstream 100 bases:

>100_bases
AGCAGCTGCAGCAGCCGCTGGCCCAGCAAACGCTGCCGATCCATCATCGCCCGCAGCCGGAGGGAACTGAACTTTATCAG
CGCTGGGCGGAACGGCAGTC

Downstream 100 bases:

>100_bases
ACCGACGGCGGCGCGTGGCAAAGATAATGCCGCGCGCTCTCGTTGGCCTTCCCCGCCCGCCCCATCGCTAAAACCCGTTT
CCTTCGCGTCGCTGGCGTTA

Product: putative cyanate transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTPALRQNLTLAVLVLTGINMRPLLTSIGPLLPDIRAASGMSYTLAALLTALPVIAMGVLALAAGWVDRYIGQKRSIALS
LLIIAAGALLREIAPNSGLLLTSALAGGIGIGIIQAAIPAVIKHLFPRRTPLVMGLWSAALMGGGGLGAAFTPWLASHSA
AWHDALAWWALPALLALFSWLAICRQLPRAPHQASASPRVAIIGQRRAWTLGLYFGLINAGYASLIAWLPPYYIQLGDSA
QYSGSLLALLTVGQTAGALLLPALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWAIACGVGLGGAFPLCLVLALD
HAGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNYTLDWSWHAICVLLLMALTLRFIPAHYPAEWRQRASDLP

Sequences:

>Translated_398_residues
MTPALRQNLTLAVLVLTGINMRPLLTSIGPLLPDIRAASGMSYTLAALLTALPVIAMGVLALAAGWVDRYIGQKRSIALS
LLIIAAGALLREIAPNSGLLLTSALAGGIGIGIIQAAIPAVIKHLFPRRTPLVMGLWSAALMGGGGLGAAFTPWLASHSA
AWHDALAWWALPALLALFSWLAICRQLPRAPHQASASPRVAIIGQRRAWTLGLYFGLINAGYASLIAWLPPYYIQLGDSA
QYSGSLLALLTVGQTAGALLLPALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWAIACGVGLGGAFPLCLVLALD
HAGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNYTLDWSWHAICVLLLMALTLRFIPAHYPAEWRQRASDLP
>Mature_397_residues
TPALRQNLTLAVLVLTGINMRPLLTSIGPLLPDIRAASGMSYTLAALLTALPVIAMGVLALAAGWVDRYIGQKRSIALSL
LIIAAGALLREIAPNSGLLLTSALAGGIGIGIIQAAIPAVIKHLFPRRTPLVMGLWSAALMGGGGLGAAFTPWLASHSAA
WHDALAWWALPALLALFSWLAICRQLPRAPHQASASPRVAIIGQRRAWTLGLYFGLINAGYASLIAWLPPYYIQLGDSAQ
YSGSLLALLTVGQTAGALLLPALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWAIACGVGLGGAFPLCLVLALDH
AGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNYTLDWSWHAICVLLLMALTLRFIPAHYPAEWRQRASDLP

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=384, Percent_Identity=66.40625, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1788092, Length=368, Percent_Identity=29.8913043478261, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42205; Mature: 42074

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPALRQNLTLAVLVLTGINMRPLLTSIGPLLPDIRAASGMSYTLAALLTALPVIAMGVL
CCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
ALAAGWVDRYIGQKRSIALSLLIIAAGALLREIAPNSGLLLTSALAGGIGIGIIQAAIPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHHHHH
VIKHLFPRRTPLVMGLWSAALMGGGGLGAAFTPWLASHSAAWHDALAWWALPALLALFSW
HHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LAICRQLPRAPHQASASPRVAIIGQRRAWTLGLYFGLINAGYASLIAWLPPYYIQLGDSA
HHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
QYSGSLLALLTVGQTAGALLLPALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACGVGLGGAFPLCLVLALDHAGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNY
HHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TLDWSWHAICVLLLMALTLRFIPAHYPAEWRQRASDLP
EEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TPALRQNLTLAVLVLTGINMRPLLTSIGPLLPDIRAASGMSYTLAALLTALPVIAMGVL
CCCHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
ALAAGWVDRYIGQKRSIALSLLIIAAGALLREIAPNSGLLLTSALAGGIGIGIIQAAIPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCHHHHHHHHHHHHH
VIKHLFPRRTPLVMGLWSAALMGGGGLGAAFTPWLASHSAAWHDALAWWALPALLALFSW
HHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LAICRQLPRAPHQASASPRVAIIGQRRAWTLGLYFGLINAGYASLIAWLPPYYIQLGDSA
HHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
QYSGSLLALLTVGQTAGALLLPALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWA
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACGVGLGGAFPLCLVLALDHAGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNY
HHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
TLDWSWHAICVLLLMALTLRFIPAHYPAEWRQRASDLP
EEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]