Click here to switch to the map view.

The map label for this gene is yfcB [H]

Identifier: 238895851

GI number: 238895851

Start: 3794076

End: 3795008

Strand: Reverse

Name: yfcB [H]

Synonym: KP1_3970

Alternate gene names: 238895851

Gene position: 3795008-3794076 (Counterclockwise)

Preceding gene: 238895853

Following gene: 238895850

Centisome position: 72.31

GC content: 56.91

Gene sequence:

>933_bases
GTGGATAAAATTTTTGTTGATGAGGCAGTCAATGAGCTGCATACCATTCAGGACATGCTGCGCTGGGCGGTAAGCCGTTT
CAGCGCTGCTAATATCTGGTACGGTCACGGGACTGATAACCCGTGGGACGAGGCGGTACAGCTGGTGCTGCCTTCACTGT
ATCTGCCGCTGGATATCCCGGAAGACATGCGCACTGCGCGCCTGACCTCCAGCGAGAAACACCGCATTGTAGAGCGGGTG
ATTCGCCGCGTGAACGAGCGTATTCCCGTCGCCTATCTGACCAACAAAGCGTGGTTCTGCGGCCATGAGTTTTACGTTGA
TGAGCGGGTGCTGGTGCCGCGCTCCCCGATTGGCGAACTGATCAATAACCAGTTTGCCGGACTGATTAACCATAAGCCGC
AGCACATCCTTGATATGTGCACCGGTAGCGGCTGCATCGCCATCGCCTGCGCCTATGCCTTCCCGGAGGCGGAAGTCGAT
GCGGTAGATATCTCCCCGGACGCGCTGGCCGTCGCCGAGCACAACGTTGAGTCCCATGGCCTGATCCATCACGTTACGCC
GATCCGTTCCGACCTGTTCCGCGATCTGCCGAAGCTGCAGTACGATCTGATCGTCACCAATCCGCCGTATGTCGATGAAG
AGGACATGGCCGATCTGCCGGAAGAGTATGAGCATGAGCCGGTGCTGGGGCTGGCCTCCGGAAGCGACGGCCTGAAGCTA
ACGCGCCGTATCCTCGGCAACGCGCCGGATTATCTCAGCGACGACGGGATTCTGATTTGTGAAGTCGGTAACAGCATGGT
ACATCTGATGGAGCAGTATCCGGATGTGCCGTTTACCTGGCTTGAGTTTGATAACGGCGGCGACGGGGTCTTTATGCTGA
CCAAACAGCAGCTGATTGACGCCCGTGCGCACTTCGGTATTTATAAAGACTAA

Upstream 100 bases:

>100_bases
GTTTTTTCCCCCGCCCCTTATCGCAAGAATGCTGATTTATCGCCGTCTTCATGGCACACTAGCCGCCGAATTTATAGCAG
AGTGTGCCCTGGAGGATGTC

Downstream 100 bases:

>100_bases
AAAAACAACACGCCAACATAACGAAAAAGATTGGAGCCGTGATGGCAGGAAATACAATTGGACAACTCTTTCGCGTCACT
ACCTTCGGCGAATCGCACGG

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDKIFVDEAVNELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERV
IRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNQFAGLINHKPQHILDMCTGSGCIAIACAYAFPEAEVD
AVDISPDALAVAEHNVESHGLIHHVTPIRSDLFRDLPKLQYDLIVTNPPYVDEEDMADLPEEYEHEPVLGLASGSDGLKL
TRRILGNAPDYLSDDGILICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKQQLIDARAHFGIYKD

Sequences:

>Translated_310_residues
MDKIFVDEAVNELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERV
IRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNQFAGLINHKPQHILDMCTGSGCIAIACAYAFPEAEVD
AVDISPDALAVAEHNVESHGLIHHVTPIRSDLFRDLPKLQYDLIVTNPPYVDEEDMADLPEEYEHEPVLGLASGSDGLKL
TRRILGNAPDYLSDDGILICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKQQLIDARAHFGIYKD
>Mature_310_residues
MDKIFVDEAVNELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERV
IRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNQFAGLINHKPQHILDMCTGSGCIAIACAYAFPEAEVD
AVDISPDALAVAEHNVESHGLIHHVTPIRSDLFRDLPKLQYDLIVTNPPYVDEEDMADLPEEYEHEPVLGLASGSDGLKL
TRRILGNAPDYLSDDGILICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKQQLIDARAHFGIYKD

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=231, Percent_Identity=29.004329004329, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082085, Length=310, Percent_Identity=91.6129032258064, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1787463, Length=194, Percent_Identity=31.4432989690722, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24582226, Length=194, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 35036; Mature: 35036

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIFVDEAVNELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
EDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGEL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCEEEECCEEECCCCHHHHH
INNQFAGLINHKPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEHNVESHG
HHHHHHHHHCCCHHHHHHHHCCCCHHEEEEEHHCCCCCCEEEECCCCEEEHHHCCCCCCC
LIHHVTPIRSDLFRDLPKLQYDLIVTNPPYVDEEDMADLPEEYEHEPVLGLASGSDGLKL
CEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCHHHCCCCEEEEECCCCHHHH
TRRILGNAPDYLSDDGILICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKQQLID
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHH
ARAHFGIYKD
HHHHCCCCCC
>Mature Secondary Structure
MDKIFVDEAVNELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
EDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGEL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCEEEECCEEECCCCHHHHH
INNQFAGLINHKPQHILDMCTGSGCIAIACAYAFPEAEVDAVDISPDALAVAEHNVESHG
HHHHHHHHHCCCHHHHHHHHCCCCHHEEEEEHHCCCCCCEEEECCCCEEEHHHCCCCCCC
LIHHVTPIRSDLFRDLPKLQYDLIVTNPPYVDEEDMADLPEEYEHEPVLGLASGSDGLKL
CEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCHHHCCCCEEEEECCCCHHHH
TRRILGNAPDYLSDDGILICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKQQLID
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHHHHH
ARAHFGIYKD
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2182772; 2969724; 7984428 [H]