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The map label for this gene is yfcE [H]

Identifier: 238895819

GI number: 238895819

Start: 3766151

End: 3766702

Strand: Reverse

Name: yfcE [H]

Synonym: KP1_3936

Alternate gene names: 238895819

Gene position: 3766702-3766151 (Counterclockwise)

Preceding gene: 238895820

Following gene: 238895818

Centisome position: 71.77

GC content: 57.43

Gene sequence:

>552_bases
ATGAAGCTGATGTTTGCCTCCGATATTCATGGTTCGCTGCCCACCACGGAACGCGTGCTTGAACGGTTCGCGCAAAGCGG
CGCCAGGTGGCTGATCATACTCGGCGATGTGCTCAATCACGGTCCGCGCAACGCGCTGCCTGAGGGGTATGCGCCGGGTG
AGGTGGCGGAGCGGTTGAACAGCGTGGCGGAACGCATTGTTGCCGTTCGCGGCAACTGCGACAGCGAAGTGGATCAGATG
CTGCTTCGTTTTCCAATGACCGCGCCCTGGCAGCAGGTGCTTAGCGAACGCTATCGCCTGTTTCTGACCCACGGGCATCT
CTATAGTCCGGATAATCTGCCGCCGCTGGCCGCTGGCGATGTCCTGGCATATGGCCATACTCATATACCGGTCGCGGAAA
AACGCGGCGCAATTTACCTCTTTAATCCCGGCTCAGTGAGTATCCCGAAAGGGGGATATTCCGCCAGCTATGGGCTGCTG
GAACAGGGGCGGCTGCAGGTTTTAGCACTCAATGATAATCAGGTTATTGCAGAGGTTGCAATTTACCCGTAA

Upstream 100 bases:

>100_bases
CAATCCAGCGTTACGTGGCGCTTTCCGCCAAACGCTGAGGCTGATAACCCGCCGCGCTTCCGCTATCATAGAGGCATCGT
AACCAGTGGAGATGGAACCT

Downstream 100 bases:

>100_bases
TTTAGCCCTCAATCATAAAGACGCGCCGCGAGAGCGCATTTAAAGTAAGGTTTCCTGATGGCGGAACAGAATCATTTGGC
AAGCACAGAATGGGTCGATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKLMFASDIHGSLPTTERVLERFAQSGARWLIILGDVLNHGPRNALPEGYAPGEVAERLNSVAERIVAVRGNCDSEVDQM
LLRFPMTAPWQQVLSERYRLFLTHGHLYSPDNLPPLAAGDVLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLL
EQGRLQVLALNDNQVIAEVAIYP

Sequences:

>Translated_183_residues
MKLMFASDIHGSLPTTERVLERFAQSGARWLIILGDVLNHGPRNALPEGYAPGEVAERLNSVAERIVAVRGNCDSEVDQM
LLRFPMTAPWQQVLSERYRLFLTHGHLYSPDNLPPLAAGDVLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLL
EQGRLQVLALNDNQVIAEVAIYP
>Mature_183_residues
MKLMFASDIHGSLPTTERVLERFAQSGARWLIILGDVLNHGPRNALPEGYAPGEVAERLNSVAERIVAVRGNCDSEVDQM
LLRFPMTAPWQQVLSERYRLFLTHGHLYSPDNLPPLAAGDVLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLL
EQGRLQVLALNDNQVIAEVAIYP

Specific function: Shows phosphodiesterase activity [H]

COG id: COG0622

COG function: function code R; Predicted phosphoesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallophosphoesterase superfamily. YfcE family [H]

Homologues:

Organism=Escherichia coli, GI1788638, Length=183, Percent_Identity=76.5027322404372, Blast_Score=298, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR020935
- InterPro:   IPR000979 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 20104; Mature: 20104

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01269 UPF0025

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMFASDIHGSLPTTERVLERFAQSGARWLIILGDVLNHGPRNALPEGYAPGEVAERLN
CCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHH
SVAERIVAVRGNCDSEVDQMLLRFPMTAPWQQVLSERYRLFLTHGHLYSPDNLPPLAAGD
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCEECCCCCCCCCCCC
VLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLLEQGRLQVLALNDNQVIAEVA
EEEECCCCCCEECCCCEEEEECCCCEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
IYP
ECC
>Mature Secondary Structure
MKLMFASDIHGSLPTTERVLERFAQSGARWLIILGDVLNHGPRNALPEGYAPGEVAERLN
CCEEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHH
SVAERIVAVRGNCDSEVDQMLLRFPMTAPWQQVLSERYRLFLTHGHLYSPDNLPPLAAGD
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHEEEEECCCEECCCCCCCCCCCC
VLAYGHTHIPVAEKRGAIYLFNPGSVSIPKGGYSASYGLLEQGRLQVLALNDNQVIAEVA
EEEECCCCCCEECCCCEEEEECCCCEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
IYP
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]