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The map label for this gene is yfbQ [H]

Identifier: 238895810

GI number: 238895810

Start: 3756001

End: 3757218

Strand: Direct

Name: yfbQ [H]

Synonym: KP1_3927

Alternate gene names: 238895810

Gene position: 3756001-3757218 (Clockwise)

Preceding gene: 238895806

Following gene: 238895811

Centisome position: 71.56

GC content: 56.4

Gene sequence:

>1218_bases
ATGTCCCCCATCGAAAAATCCAGCAAGTTAGAGAACGTCTGTTATGACATCCGCGGCCCGGTTCTGAAAGAAGCCAAACG
TCTTGAAGAAGAAGGCAATAAGGTTCTGAAACTGAACATCGGCAACCCGGCGCCATTCGGCTTCGAGGCCCCTGACGAGA
TCCTCGTCGACGTCATCCGCAATTTGCCTACCGCCCAGGGTTACTGCGATTCGAAAGGATTGTACTCGGCGCGTAAAGCT
ATCATGCAGCATTACCAGGCCCGGGGTATGCGCGATGTCACGGTGGAAGACATCTATATCGGCAACGGCGTGTCCGAACT
GATTGTGCAGGCGATGCAGGCGCTGTTAAACAGCGGCGATGAGATGCTGGTTCCCGCCCCGGACTACCCGCTGTGGACGG
CGGCGGTGTCGCTTTCCAGCGGCAAAGCGGTGCACTATCTGTGTGACGAATCCTCTGACTGGTTCCCGGATCTGGACGAC
ATCCGCGCAAAAATCACACCGCGCACCCGCGGGATCGTGATCATTAACCCTAACAACCCCACCGGCGCGGTCTATTCCAA
AGAATTGCTGCAAGAGATCGTGGAGATCGCTCGTCAGCATAATCTGATCATTTTCGCCGATGAAATTTACGACAAGATCC
TCTACGACGAAGCCCAGCATCACTCTATTGCCGCCCTTGCGCCGGACCTGCTGACGGTGACCTTTAACGGATTGTCGAAA
ACCTACCGCGTTGCCGGCTTCCGTCAGGGCTGGATGGTGCTGAATGGCCCGAAAAAACACGCGAAGGGCTATATCGAAGG
GCTGGAGATGCTGGCTTCAATGCGCCTATGCGCCAACGTGCCGGCCCAGCATGCTATCCAGACGGCGCTGGGCGGCTATC
AGAGCATCAGCGAATTCATCATCCCCGGCGGACGCCTGTATGAACAACGCAACCGCGCCTGGGAGCTTATCAACGATATT
CCGGGCGTCTCCTGCGTGAAGCCAAAAGGCGCGCTGTATATGTTCCCGAAAATCGACGCCAAACGCTTCAATATTCATGA
CGACCAGAAAATGGTGCTCGACTTCCTGCTGCAGGAGAAAGTCCTGCTGGTGCAAGGCACCGCCTTTAACTGGCCGTGGC
CGGATCACGTACGCATCGTGACCCTGCCGCGCGAAGACGACCTGGAGATGGCTATCTCCCGCTTTGGCCGCTTCCTCTCC
GGCTACCATCAGCTTTAA

Upstream 100 bases:

>100_bases
TCTCCTGCAAAGCCTTCAAAACAGCGGGGAGGGGGAGTACATTGTTCCGTGCTGACTTCCACGGCAGGGAGTGGCGATAA
CAGCTAAAAGGTCAAGATTC

Downstream 100 bases:

>100_bases
TCGCGCCGCCGCCGGCATTTGCATCCGGCGGCGATCCCTGCGCACAATGGAACCCGATGTTGTCACTGATTAAGGGTCCC
TATGAGTCAGAGTCATTTCT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLQEIVEIARQHNLIIFADEIYDKILYDEAQHHSIAALAPDLLTVTFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFIIPGGRLYEQRNRAWELINDI
PGVSCVKPKGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHVRIVTLPREDDLEMAISRFGRFLS
GYHQL

Sequences:

>Translated_405_residues
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLQEIVEIARQHNLIIFADEIYDKILYDEAQHHSIAALAPDLLTVTFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFIIPGGRLYEQRNRAWELINDI
PGVSCVKPKGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHVRIVTLPREDDLEMAISRFGRFLS
GYHQL
>Mature_404_residues
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAI
MQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDI
RAKITPRTRGIVIINPNNPTGAVYSKELLQEIVEIARQHNLIIFADEIYDKILYDEAQHHSIAALAPDLLTVTFNGLSKT
YRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFIIPGGRLYEQRNRAWELINDIP
GVSCVKPKGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHVRIVTLPREDDLEMAISRFGRFLSG
YHQL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=26.9633507853403, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI19263340, Length=463, Percent_Identity=24.4060475161987, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=25.5434782608696, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4885351, Length=437, Percent_Identity=23.5697940503432, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI95147551, Length=171, Percent_Identity=29.2397660818713, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI169881279, Length=171, Percent_Identity=29.2397660818713, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI56713256, Length=235, Percent_Identity=26.3829787234043, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713254, Length=206, Percent_Identity=27.1844660194175, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI169881281, Length=161, Percent_Identity=31.055900621118, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI149944424, Length=214, Percent_Identity=26.1682242990654, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=405, Percent_Identity=96.0493827160494, Blast_Score=816, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=26.984126984127, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786816, Length=225, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=29.4594594594595, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71981209, Length=458, Percent_Identity=25.764192139738, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=205, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=205, Percent_Identity=29.2682926829268, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=26.962457337884, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=178, Percent_Identity=28.6516853932584, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=27.5, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=354, Percent_Identity=27.683615819209, Blast_Score=126, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=303, Percent_Identity=23.7623762376238, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=27.1276595744681, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI45551451, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641770, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641760, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641768, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641766, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24641764, Length=460, Percent_Identity=26.304347826087, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28573069, Length=230, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646114, Length=230, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573067, Length=230, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573065, Length=230, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45484; Mature: 45353

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLQEIVEIARQHNLIIFADEIYDKILYDEAQHHSIAALAPDLLTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
IPGGRLYEQRNRAWELINDIPGVSCVKPKGALYMFPKIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHVRIVTLPREDDLEMAISRFGRFLSGYHQL
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNP
CEEEECCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHEEECCCCCEEEEECCCCC
TGAVYSKELLQEIVEIARQHNLIIFADEIYDKILYDEAQHHSIAALAPDLLTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
IPGGRLYEQRNRAWELINDIPGVSCVKPKGALYMFPKIDAKRFNIHDDQKMVLDFLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
VLLVQGTAFNWPWPDHVRIVTLPREDDLEMAISRFGRFLSGYHQL
EEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]