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The map label for this gene is yfaX [H]

Identifier: 238895780

GI number: 238895780

Start: 3725199

End: 3725984

Strand: Reverse

Name: yfaX [H]

Synonym: KP1_3888

Alternate gene names: 238895780

Gene position: 3725984-3725199 (Counterclockwise)

Preceding gene: 238895781

Following gene: 238895779

Centisome position: 70.99

GC content: 58.4

Gene sequence:

>786_bases
ATGTTGGAATCAACGAAAGTCCCGGCGCTGACCCGCGCGATTGAGATCCTCAATTTAATTGGCCGCATCGGCCCCTGCAG
CGCGGCGACGATAATAGCGGAGCTGGGGATCCCGAAAAGCACGGTGTATCTGCTGCTGGGCGAGCTGAAAAAGCAGCGCT
TCATCAGTATGGATAATCAGGATAACTACTGCCTGTGGACCAAGTTGGTGGAGCTGGCCGGGCAGGCGCTGAGCAAAATG
GACCTGCGCGAGCTGGCGCGGCCGCGCCTCACCCGGCTGATGGATGAGTGCGGCCTGCTTTGTCACTTGGGCATTATCGA
TCAGGGTAACGCCTACTACATTCTGAAAATTGAGTCTCCCGCCACCATCAGCGTGCGCTCGCATGAGGGTAAGAGCCTGT
CTCTTTACCGCTCCGGGATCGGCAAATGTTTGCTGGCCTGGCAGCCCGCCAGCGTTCAGGCGTCGATTATCGAAGACCTA
CAGTGGGAGCGGGCCACGCCAACGACCATCACCGATGCTCAACAGCTGCGGGAGGAGCTGGGGCGGATCCGCGCCCGGGG
CTGGAGCTTTGATAATGGCGAGGACTATCCGGATGTGCGCTGCGTGGCTGCCCCGGTATTTAACGCCAATAACGACCTGA
CCGCCGCCATCTCGGTGGTGGGTACCCGTCTGCAAATCAATGAAGACAATCGCGATTACCTGGCTGGTAAGGCGATTGCC
TGCGCGAAAGATATTTCACGTCTGCTGGGGTGGAAAAGCCCCTTCGAACAACTCGCCTCATCATAA

Upstream 100 bases:

>100_bases
GGTCCAGTATACGGGAAAACGATTGCCCCGCGATGTCGCTCACACTTTACCGCCCGGACAATCGCAACACTGATTCCAGT
ATTCAGGATTGGAGTCCAGT

Downstream 100 bases:

>100_bases
GGAGAACATCATGACCCTACCGAAAATTAAACACGTCCGCGCCTGGTTCATCGGCGGCGCCACAGCAGAGCAGGGCGCCG
GCGGCGGCGATTACCATGAC

Product: putative regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLESTKVPALTRAIEILNLIGRIGPCSAATIIAELGIPKSTVYLLLGELKKQRFISMDNQDNYCLWTKLVELAGQALSKM
DLRELARPRLTRLMDECGLLCHLGIIDQGNAYYILKIESPATISVRSHEGKSLSLYRSGIGKCLLAWQPASVQASIIEDL
QWERATPTTITDAQQLREELGRIRARGWSFDNGEDYPDVRCVAAPVFNANNDLTAAISVVGTRLQINEDNRDYLAGKAIA
CAKDISRLLGWKSPFEQLASS

Sequences:

>Translated_261_residues
MLESTKVPALTRAIEILNLIGRIGPCSAATIIAELGIPKSTVYLLLGELKKQRFISMDNQDNYCLWTKLVELAGQALSKM
DLRELARPRLTRLMDECGLLCHLGIIDQGNAYYILKIESPATISVRSHEGKSLSLYRSGIGKCLLAWQPASVQASIIEDL
QWERATPTTITDAQQLREELGRIRARGWSFDNGEDYPDVRCVAAPVFNANNDLTAAISVVGTRLQINEDNRDYLAGKAIA
CAKDISRLLGWKSPFEQLASS
>Mature_261_residues
MLESTKVPALTRAIEILNLIGRIGPCSAATIIAELGIPKSTVYLLLGELKKQRFISMDNQDNYCLWTKLVELAGQALSKM
DLRELARPRLTRLMDECGLLCHLGIIDQGNAYYILKIESPATISVRSHEGKSLSLYRSGIGKCLLAWQPASVQASIIEDL
QWERATPTTITDAQQLREELGRIRARGWSFDNGEDYPDVRCVAAPVFNANNDLTAAISVVGTRLQINEDNRDYLAGKAIA
CAKDISRLLGWKSPFEQLASS

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788581, Length=260, Percent_Identity=83.0769230769231, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1790752, Length=251, Percent_Identity=33.0677290836653, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=29.5275590551181, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786468, Length=215, Percent_Identity=32.5581395348837, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082359, Length=249, Percent_Identity=26.1044176706827, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786715, Length=248, Percent_Identity=28.6290322580645, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789999, Length=231, Percent_Identity=28.1385281385281, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28865; Mature: 28865

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESTKVPALTRAIEILNLIGRIGPCSAATIIAELGIPKSTVYLLLGELKKQRFISMDNQ
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
DNYCLWTKLVELAGQALSKMDLRELARPRLTRLMDECGLLCHLGIIDQGNAYYILKIESP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCC
ATISVRSHEGKSLSLYRSGIGKCLLAWQPASVQASIIEDLQWERATPTTITDAQQLREEL
CEEEEECCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GRIRARGWSFDNGEDYPDVRCVAAPVFNANNDLTAAISVVGTRLQINEDNRDYLAGKAIA
HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEEEECCCCCHHHHHHHHH
CAKDISRLLGWKSPFEQLASS
HHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MLESTKVPALTRAIEILNLIGRIGPCSAATIIAELGIPKSTVYLLLGELKKQRFISMDNQ
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
DNYCLWTKLVELAGQALSKMDLRELARPRLTRLMDECGLLCHLGIIDQGNAYYILKIESP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCC
ATISVRSHEGKSLSLYRSGIGKCLLAWQPASVQASIIEDLQWERATPTTITDAQQLREEL
CEEEEECCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GRIRARGWSFDNGEDYPDVRCVAAPVFNANNDLTAAISVVGTRLQINEDNRDYLAGKAIA
HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEEEECCCCCHHHHHHHHH
CAKDISRLLGWKSPFEQLASS
HHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]