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The map label for this gene is nylB [H]

Identifier: 238895747

GI number: 238895747

Start: 3681124

End: 3682542

Strand: Direct

Name: nylB [H]

Synonym: KP1_3851

Alternate gene names: 238895747

Gene position: 3681124-3682542 (Clockwise)

Preceding gene: 238895745

Following gene: 238895749

Centisome position: 70.14

GC content: 59.48

Gene sequence:

>1419_bases
GTGCGAATGAATACTGTAGGGTTTTCATCCTTTTTCTCCCTTAAGGGGGAAAATCCCCCATGTGCTGATTTTAGCCGGCG
CGCGCCGATTTATATACTGCGCAGCGAATCTATGGCAAACGAGGAAATGACAATGATAAGAAAACCACTGGCCCTGGCGT
TAATATTGGCGGCGCTGCCGGCGGCGGCAATGGCGCAACACTGCGGCAGCCTGACGCTGGATGTCTGCCCAACGCCTTAC
GATCAAACGCTACCCGCGGCCAAAGACATGCTCAGCTGGGATCAGACTTCACGCGTGATTGGCTTTCGCAATGACTATCG
CAACTATGCCGGCGATGTCTTCCGCCACGGCGCCTCGACGCCGCTGGAGCGCGCTGAAAAACAACTGACCGATGCCCGCT
ATACGCTCAACGGCCACACCTGGAATTTGCAGGATTACCTGAAGCGCGAGAACGTCAGCGGTATGCTGGTGCTGAAAGAT
GGTAAAGTCGCCTGGAAATATCTCGCCGAAGGTAATACCGACACCACCCTGTGGACCTCGCGCTCGGTAGGCAAATCGGT
GGTCTCGACGCTGGTCGGTATCGCCATTCAACAGGGTAAAATCCACTCCCTTGATGACCTGATTACCGTTTATGAACCCG
AACTGAAAGGCACCGCCTGGGACGGCGTAACGCTGAAGCAGTTGATTCAACACACCAGCGGGGTGGAATGGAATGAAGAC
TACACCGACCCGCAGTCGCATTTCGCCCGCCTGACCCAGTGTGAAGCGCACCCCGGCGCCTATGCCTGCGTGCGTAAGAT
CGTCACCGGCCTGGCGCGTCAACACCCGGCGGGCGAGCAGTGGTCCTACTCTTCCGGCGGCGCCTGGCTGCTTGGGGATA
TCCTGGAGCGCGCCACCGGCATGTCGCTGGCCGCCTGGCTTGAACAGGCTCTATGGCAGCCGGCCGGGATGGCCCACGAC
GGCGTGTGGCATGCTTATCAGCAAGGGAAGCACGACGTCGGCGCCCACGGCTTTAACGCCACCCTTGAAGACTGGGGCCG
CTTTGGTGAATTCGTCGCCCGTGACGGTCGGTTAAGCAATGGCAAACAGCTGGTGCCGACTGGCTGGTTCGATCAAGCCG
CCAGCTGGACCAAGGCGCTAAACTCGGTCTCGGCAGCGCATCCGGAGGGTATTTACGGCTATCAGTGGTGGAATAACGCG
ATTCCGGCGAATGCGCAAAACGTCCAGCCGACGCCGCAGGAAGGGCTTAAAGGGTCGCTGTGGGCGCTGGGGATCTACGG
CCAGGTGATCATGGTGAACCGCGCGGAACACCTGGTGATCGTCCAGTGGTCGACCTGGCCGCAGGCGGAACCTTCCTTCA
ACGCTCAGCCGTTGGAAGCGGCGCTGATGTACAGCGCCATTGCCCGCGAGCTGCGTTAA

Upstream 100 bases:

>100_bases
TAGTCCAGCAGATCGCGCAGCGTGGTCCGGTCTTTAGCTAAACGAATGGCCGCCTGCGACAGGCTGCCGGTCTCAGCAAT
CGTCGCGAAGGCTTCAATCT

Downstream 100 bases:

>100_bases
CTCCCCGCTCCTTGCCGCTCAGCCGGCGAGGAGCGTGTCGGCATTCAGCGCCAGGTGTTGCAGCAGGATAATGGTTTTAG
CATCCATGATCTCGCCATCG

Product: putative beta-lactamase

Products: NA

Alternate protein names: Nylon oligomers-degrading enzyme EII [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MRMNTVGFSSFFSLKGENPPCADFSRRAPIYILRSESMANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPY
DQTLPAAKDMLSWDQTSRVIGFRNDYRNYAGDVFRHGASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKD
GKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIQQGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNED
YTDPQSHFARLTQCEAHPGAYACVRKIVTGLARQHPAGEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHD
GVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRLSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYQWWNNA
IPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR

Sequences:

>Translated_472_residues
MRMNTVGFSSFFSLKGENPPCADFSRRAPIYILRSESMANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPY
DQTLPAAKDMLSWDQTSRVIGFRNDYRNYAGDVFRHGASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKD
GKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIQQGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNED
YTDPQSHFARLTQCEAHPGAYACVRKIVTGLARQHPAGEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHD
GVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRLSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYQWWNNA
IPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR
>Mature_472_residues
MRMNTVGFSSFFSLKGENPPCADFSRRAPIYILRSESMANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPY
DQTLPAAKDMLSWDQTSRVIGFRNDYRNYAGDVFRHGASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKD
GKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIQQGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNED
YTDPQSHFARLTQCEAHPGAYACVRKIVTGLARQHPAGEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHD
GVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRLSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYQWWNNA
IPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.1.46 [H]

Molecular weight: Translated: 52323; Mature: 52323

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMNTVGFSSFFSLKGENPPCADFSRRAPIYILRSESMANEEMTMIRKPLALALILAALP
CCCCCCCCHHHHEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTSRVIGFRNDYRNYAGDVFRHGAST
HHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
PLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKDGKVAWKYLAEGNTDTTLWTS
HHHHHHHHHHHCEEEECCCEECHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCEEEEC
RSVGKSVVSTLVGIAIQQGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNED
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
YTDPQSHFARLTQCEAHPGAYACVRKIVTGLARQHPAGEQWSYSSGGAWLLGDILERATG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
MSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRLSN
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYQWWNNAIPANAQNVQPTPQEGLKGSL
CCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCE
WALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR
EEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRMNTVGFSSFFSLKGENPPCADFSRRAPIYILRSESMANEEMTMIRKPLALALILAALP
CCCCCCCCHHHHEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTSRVIGFRNDYRNYAGDVFRHGAST
HHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
PLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKDGKVAWKYLAEGNTDTTLWTS
HHHHHHHHHHHCEEEECCCEECHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCEEEEC
RSVGKSVVSTLVGIAIQQGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNED
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
YTDPQSHFARLTQCEAHPGAYACVRKIVTGLARQHPAGEQWSYSSGGAWLLGDILERATG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
MSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRLSN
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYQWWNNAIPANAQNVQPTPQEGLKGSL
CCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCE
WALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR
EEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6646204; 6389532; 2512123 [H]